Response to comment on "human white blood cells synthesize morphine: CYP2D6 modulation" [2]

Journal of Immunology

Volumn 176, Issue 10, 2006, Pages 5704-

  Zhu, Wei ^a   Cadet, Patrick ^a   Mantione, Kirk J ^a   Kream, Richard M ^b   Stefano, George B ^a  

^a STATE UNIVERSITY OF NEW YORK   (United States)

^b SUNY DOWNSTATE MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); CARBON 13; CATECHOL METHYLTRANSFERASE; CYTOCHROME P450 2D6; DOPAMINE; LEVODOPA; MORPHINE; TRITIUM; TRITIUM OXIDE; TYRAMINE; TYROSINE 3 MONOOXYGENASE;

ASSAY; BIOSYNTHESIS; DRUG SYNTHESIS; ENZYME ACTIVE SITE; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LETTER; LEUKOCYTE; NEUROBLASTOMA CELL; PRIORITY JOURNAL; RADIOIMMUNOASSAY; TANDEM MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY;

EID: 33646468924     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.176.10.5704     Document Type: Letter

References (9)

1. Boettcher, C., M. Fellermeier, C. Boerrcher, B. Drager, and M. H. Zenk. 2005. How human neuroblastoma cells make morphine. Proc. Natl. Acad. Sci. USA 102: 8495-8500.
2. Poeaknapo, C., J. Schmidt, M. Brandsch, B. Drager, and M. H. Zenk. 2004. Endogenous formarion of morphine in human cells. Proc. Natl. Acad. Sci. USA 101: 14091-14096.
3. Presgraves, S. P., T. Ahmed, S. Borwege, and J. N. Joyce. 2004. Terminally differentiated SH-SY5Y cells provide a model system for studying neuroprotective effects of dopamine agonists. Neurotox. Res. 5: 579-598.
4. 3H]-tyrosine by charcoal. Life Sci. 39: 2185-2189.
5. Zhu, W., P. Cadet, G. Baggerman, K. J. Mantione, and G. B. Stefano. 2005. Human white blood cells synthesize morphine: CYP2D6 modulation. J. Immunol. 175: 7357-7362.
6. Funae, Y., W. Kishimoto, T. Cho, T. Niwa, and T. Hiroi. 2003. CYP2D in the brain. Drug Metab. Pharmacokinet. 18: 337-349.
7. Hiroi, T., S. Imaoka, and Y. Funae. 1998. Dopamine formation from tyramine by CYP2D6. Biochem. Biophys. Res. Commun. 249: 838-843.
8. Guengerich, F. P., G. P. Miller, I. H. Hanna, H. Sato, and M. V. Martin. 2002. Oxidation of methoxyphenethylamines by cytochrome P450 2D6: analysis of rate-limiting steps. J. Biol. Chem. 277: 33711-33719.
9. Miller, G. P., I. H. Hanna, Y. Nishimura, and F. P. Guengerich. 2001. Oxidation of phenethylamine derivatives by cytochrome P450 2D6: the issue of substrate protonation in binding and catalysis. Biochemistry 40: 14215-14223.