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Volumn 277, Issue 37, 2002, Pages 33711-33719

Oxidation of methoxyphenethylamines by cytochrome P450 2D6: Analysis of rate-limiting steps

(5) Peter Guengerich, F a,b,c,d Miller, Grover P a,b,c,d Hanna, Imad H a,b,c,d Sato, Hideaki a,b,c,d Martin, Martha V a,b,c,d

a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE (United States)

b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES (United States)

c MERCK RESEARCH LABORATORIES (United States)

d KYUSHU UNIVERSITY (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; COMPUTER SIMULATION; DEUTERIUM; DRUG DOSAGE; HYDROXYLATION; ISOTOPES;

RATE LIMITING STEPS;

OXIDATION;

CYTOCHROME P450 2D6; DEUTERIUM; DOPAMINE; FERROUS ION; OXYGEN; PHENETHYLAMINE DERIVATIVE;

ARTICLE; CATALYSIS; CHEMICAL BOND; DEMETHYLATION; ENZYME MECHANISM; HYDROXYLATION; MOLECULAR INTERACTION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTON TRANSPORT; STEADY STATE;

CATALYSIS; CYTOCHROME P-450 CYP2D6; DEALKYLATION; HYDROGEN PEROXIDE; KINETICS; NADP; OXIDATION-REDUCTION; TYRAMINE;

EID: 0037072798 PISSN: 00219258 EISSN: None Source Type: Journal
DOI: 10.1074/jbc.M205146200 Document Type: Article

Times cited : (59)

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