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Volumn 290, Issue 4, 2006, Pages

Modulation of connexin43 alters expression of osteoblastic differentiation markers

Author keywords

Alkaline phosphatase activity; Gap junction communication; hFOB 1.19; Osteocalcin; Osteopontin

Indexed keywords

ALKALINE PHOSPHATASE; COLLAGEN TYPE 1; COMPLEMENTARY DNA; CONNEXIN 43; CONNEXIN 45; OSTEOCALCIN; OSTEOPONTIN; PLASMID VECTOR; TRANSCRIPTION FACTOR RUNX2;

EID: 33646422489     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00428.2005     Document Type: Article
Times cited : (67)

References (35)
  • 1
    • 0025351711 scopus 로고
    • Membrane modifications in chick osteoclasts revealed by freezefracture replicas
    • Akisaka T, Yoshida H, Kogaya Y, Kim S, Yamamoto M, and Kataoka K. Membrane modifications in chick osteoclasts revealed by freezefracture replicas. Am J Anat 188: 381-392, 1990.
    • (1990) Am J Anat , vol.188 , pp. 381-392
    • Akisaka, T.1    Yoshida, H.2    Kogaya, Y.3    Kim, S.4    Yamamoto, M.5    Kataoka, K.6
  • 2
    • 0032323828 scopus 로고    scopus 로고
    • Advances in the osteoblast lineage
    • Aubin JE. Advances in the osteoblast lineage. Biochem Cell Biol 76: 899-910, 1998.
    • (1998) Biochem Cell Biol , vol.76 , pp. 899-910
    • Aubin, J.E.1
  • 4
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254, 1976.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 5
    • 0027850391 scopus 로고
    • Relationship between the expression of the gap junction protein and osteoblast phenotype in a human osteoblastic cell line during cell proliferation
    • Chiba H, Sawada N, Oyamada M, Kojima T, Nomura S, Ishii S, and Mori M. Relationship between the expression of the gap junction protein and osteoblast phenotype in a human osteoblastic cell line during cell proliferation. Cell Struct Funct 18: 419-426, 1993.
    • (1993) Cell Struct Funct , vol.18 , pp. 419-426
    • Chiba, H.1    Sawada, N.2    Oyamada, M.3    Kojima, T.4    Nomura, S.5    Ishii, S.6    Mori, M.7
  • 7
    • 0034095163 scopus 로고    scopus 로고
    • Differentiation of human fetal osteoblastic cells and gap junctional intercellular communication
    • Donahue HJ, Li Z, Zhou Z, and Yellowley CE. Differentiation of human fetal osteoblastic cells and gap junctional intercellular communication. Am J Physiol Cell Physiol 278: C315-C322, 2000.
    • (2000) Am J Physiol Cell Physiol , vol.278
    • Donahue, H.J.1    Li, Z.2    Zhou, Z.3    Yellowley, C.E.4
  • 8
    • 0033662188 scopus 로고    scopus 로고
    • Cbfa1: A molecular switch in osteoblast biology
    • Ducy P. Cbfa1: a molecular switch in osteoblast biology. Dev Dyn 219: 461-471, 2000.
    • (2000) Dev Dyn , vol.219 , pp. 461-471
    • Ducy, P.1
  • 10
    • 0026521313 scopus 로고
    • Human osteosarcoma cells spontaneously release matrixvesicle-like structures with the capacity to mineralize
    • Fedde KN. Human osteosarcoma cells spontaneously release matrixvesicle-like structures with the capacity to mineralize. Bone Miner 17: 145-151, 1992.
    • (1992) Bone Miner , vol.17 , pp. 145-151
    • Fedde, K.N.1
  • 11
    • 0025334411 scopus 로고
    • Molecular characterization and functional expression of the human cardiac gap junction channel
    • Fishman GI, Spray DC, and Leinwand LA. Molecular characterization and functional expression of the human cardiac gap junction channel. J Cell Biol 111: 589-598, 1990.
    • (1990) J Cell Biol , vol.111 , pp. 589-598
    • Fishman, G.I.1    Spray, D.C.2    Leinwand, L.A.3
  • 12
    • 0028242767 scopus 로고
    • Effects of ascorbic acid on collagen matrix formation and osteoblast differentiation in murine MC3T3-E1 cells
    • Franceschi RT, Iyer BS, and Cui Y. Effects of ascorbic acid on collagen matrix formation and osteoblast differentiation in murine MC3T3-E1 cells. J Bone Miner Res 9: 843-854, 1994.
    • (1994) J Bone Miner Res , vol.9 , pp. 843-854
    • Franceschi, R.T.1    Iyer, B.S.2    Cui, Y.3
  • 13
    • 0028947930 scopus 로고
    • Development and characterization of a conditionally immortalized human fetal osteoblastic cell line
    • Harris SA, Enger RJ, Riggs BL, and Spelsberg TC. Development and characterization of a conditionally immortalized human fetal osteoblastic cell line. J Bone Miner Res 10: 178-186, 1995.
    • (1995) J Bone Miner Res , vol.10 , pp. 178-186
    • Harris, S.A.1    Enger, R.J.2    Riggs, B.L.3    Spelsberg, T.C.4
  • 15
    • 0030947454 scopus 로고    scopus 로고
    • Connexin46 is retained as monomers in a trans-Golgi compartment of osteoblastic cells
    • Koval M, Harley JE, Hick E, and Steinberg TH. Connexin46 is retained as monomers in a trans-Golgi compartment of osteoblastic cells. J Cell Biol 137: 847-857, 1997.
    • (1997) J Cell Biol , vol.137 , pp. 847-857
    • Koval, M.1    Harley, J.E.2    Hick, E.3    Steinberg, T.H.4
  • 17
    • 0034645070 scopus 로고    scopus 로고
    • Connexin 43 deficiency causes delayed ossification, craniofacial abnormalities, and osteoblast dysfunction
    • Lecanda F, Warlow PM, Sheikh S, Furlan F, Steinberg TH, and Civitelli R. Connexin 43 deficiency causes delayed ossification, craniofacial abnormalities, and osteoblast dysfunction. J Cell Biol 151: 931-944, 2000.
    • (2000) J Cell Biol , vol.151 , pp. 931-944
    • Lecanda, F.1    Warlow, P.M.2    Sheikh, S.3    Furlan, F.4    Steinberg, T.H.5    Civitelli, R.6
  • 18
    • 33646424612 scopus 로고    scopus 로고
    • Restoration of connexin 43 alters breast cancer cell metastatic potential to bone by down regulation of osteopontin and connexin 32
    • Abstract no. 0186
    • Li Z, Zhou Z, Welch DR, and Donahue HJ. Restoration of connexin 43 alters breast cancer cell metastatic potential to bone by down regulation of osteopontin and connexin 32 (Abstract no. 0186). Transactions of the 48th Annual Meeting of the Orthopaedic Research Society, vol. 27, 2002.
    • (2002) Transactions of the 48th Annual Meeting of the Orthopaedic Research Society , vol.27
    • Li, Z.1    Zhou, Z.2    Welch, D.R.3    Donahue, H.J.4
  • 19
    • 0027143339 scopus 로고
    • Expression of gap junction connexin 43 and connexin 43 mRNA in different regional tissues of intestine in dog
    • Li Z, Zhou Z, and Daniel EE. Expression of gap junction connexin 43 and connexin 43 mRNA in different regional tissues of intestine in dog. Am J Physiol Gastrointest Liver Physiol 265: G911-G916, 1993.
    • (1993) Am J Physiol Gastrointest Liver Physiol , vol.265
    • Li, Z.1    Zhou, Z.2    Daniel, E.E.3
  • 20
    • 0032725056 scopus 로고    scopus 로고
    • Inhibiting gap junctional intercellular communication alters expression of differentiation markers in osteoblastic cells
    • Li Z, Zhou Z, Yellowley CE, and Donahue HJ. Inhibiting gap junctional intercellular communication alters expression of differentiation markers in osteoblastic cells. Bone 25: 661-666, 1999.
    • (1999) Bone , vol.25 , pp. 661-666
    • Li, Z.1    Zhou, Z.2    Yellowley, C.E.3    Donahue, H.J.4
  • 21
    • 0029742875 scopus 로고    scopus 로고
    • The role of gap junction membrane channels in development
    • Lo CW. The role of gap junction membrane channels in development. J Bioenerg Biomembr 28: 379-385, 1996.
    • (1996) J Bioenerg Biomembr , vol.28 , pp. 379-385
    • Lo, C.W.1
  • 22
    • 0023880883 scopus 로고
    • Developmental expression of 44-kDa bone phosphoprotein (osteopontin) and bone gamma-carboxyglutamic acid (Gla)-containing protein (osteocalcin) in calcifying tissues of rat
    • Mark MP, Butler WT, Prince CW, Finkelman RD, and Ruch JV. Developmental expression of 44-kDa bone phosphoprotein (osteopontin) and bone gamma-carboxyglutamic acid (Gla)-containing protein (osteocalcin) in calcifying tissues of rat. Differentiation 37: 123-136, 1988.
    • (1988) Differentiation , vol.37 , pp. 123-136
    • Mark, M.P.1    Butler, W.T.2    Prince, C.W.3    Finkelman, R.D.4    Ruch, J.V.5
  • 23
    • 0033011398 scopus 로고    scopus 로고
    • Antisense oligonucleotide blockade of connexin expression during embryonic bone formation: Evidence of functional compensation within a multigene family
    • Minkoff R, Bales ES, Kerr CA, and Struss WE. Antisense oligonucleotide blockade of connexin expression during embryonic bone formation: evidence of functional compensation within a multigene family. Dev Genet 24: 43-56, 1999.
    • (1999) Dev Genet , vol.24 , pp. 43-56
    • Minkoff, R.1    Bales, E.S.2    Kerr, C.A.3    Struss, W.E.4
  • 24
    • 0027968667 scopus 로고
    • Gap junction proteins exhibit early and specific expression during intramembranous bone formation in the developing chick mandible
    • Minkoff R, Rundus VR, Parker SB, Hertzberg EL, Laing JG, and Beyer EC. Gap junction proteins exhibit early and specific expression during intramembranous bone formation in the developing chick mandible. Anat Embryol (Berl) 190: 231-241, 1994.
    • (1994) Anat Embryol (Berl) , vol.190 , pp. 231-241
    • Minkoff, R.1    Rundus, V.R.2    Parker, S.B.3    Hertzberg, E.L.4    Laing, J.G.5    Beyer, E.C.6
  • 25
    • 0035140021 scopus 로고    scopus 로고
    • Gap-junctional communication mediates parathyroid hormone stimulation of mineralization in osteoblastic cultures
    • Schiller PC, D'Ippolito G, Balkan W, Roos BA, and Howard GA. Gap-junctional communication mediates parathyroid hormone stimulation of mineralization in osteoblastic cultures. Bone 28: 38-44, 2001.
    • (2001) Bone , vol.28 , pp. 38-44
    • Schiller, P.C.1    D'Ippolito, G.2    Balkan, W.3    Roos, B.A.4    Howard, G.A.5
  • 26
    • 0035957918 scopus 로고    scopus 로고
    • Inhibition of gap-junctional communication induces the trans-differentiation of osteoblasts to an adipocytic phenotype in vitro
    • Schiller PC, D'Ippolito G, Brambilla R, Roos BA, and Howard GA. Inhibition of gap-junctional communication induces the trans-differentiation of osteoblasts to an adipocytic phenotype in vitro. J Biol Chem 276: 14133-14138, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 14133-14138
    • Schiller, P.C.1    D'Ippolito, G.2    Brambilla, R.3    Roos, B.A.4    Howard, G.A.5
  • 27
    • 0030833934 scopus 로고    scopus 로고
    • Parathyroid hormone upregulation of connexin 43 gene expression in osteoblasts depends on cell phenotype
    • Schiller PC, Roos BA, and Howard GA. Parathyroid hormone upregulation of connexin 43 gene expression in osteoblasts depends on cell phenotype. J Bone Miner Res 12: 2005-2013, 1997.
    • (1997) J Bone Miner Res , vol.12 , pp. 2005-2013
    • Schiller, P.C.1    Roos, B.A.2    Howard, G.A.3
  • 28
    • 18044385345 scopus 로고    scopus 로고
    • Cell-cell interactions in regulating osteogenesis and osteoblast function
    • Stains JP and Civitelli R. Cell-cell interactions in regulating osteogenesis and osteoblast function. Birth Defects Res C Embryo Today 75: 72-80, 2005.
    • (2005) Birth Defects Res C Embryo Today , vol.75 , pp. 72-80
    • Stains, J.P.1    Civitelli, R.2
  • 29
    • 0041589372 scopus 로고    scopus 로고
    • Gap junctional communication modulates gene transcription by altering the recruitment of Sp1 and Sp3 to connexin-response elements in osteoblast promoters
    • Stains JP, Lecanda F, Screen J, Towler DA, and Civitelli R. Gap junctional communication modulates gene transcription by altering the recruitment of Sp1 and Sp3 to connexin-response elements in osteoblast promoters. J Biol Chem 278: 24377-24387, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 24377-24387
    • Stains, J.P.1    Lecanda, F.2    Screen, J.3    Towler, D.A.4    Civitelli, R.5
  • 31
    • 0036354866 scopus 로고    scopus 로고
    • Further characterization of human fetal osteoblastic hFOB 1.19 and hFOB/ER alpha cells: Bone formation in vivo and karyotype analysis using multicolor fluorescent in situ hybridization
    • Subramaniam M, Jalal SM, Rickard DJ, Harris SA, Bolander ME, and Spelsberg TC. Further characterization of human fetal osteoblastic hFOB 1.19 and hFOB/ER alpha cells: bone formation in vivo and karyotype analysis using multicolor fluorescent in situ hybridization. J Cell Biochem 87: 9-15, 2002.
    • (2002) J Cell Biochem , vol.87 , pp. 9-15
    • Subramaniam, M.1    Jalal, S.M.2    Rickard, D.J.3    Harris, S.A.4    Bolander, M.E.5    Spelsberg, T.C.6
  • 32
    • 0043069738 scopus 로고    scopus 로고
    • Reduced gap junctional intercellular communication and altered biological effects in mouse osteoblast and rat liver oval cell lines transfected with dominant-negative connexin 43
    • Upham BL, Suzuki J, Chen G, Wang Y, McCabe LR, Chang CC, Krutovskikh VA, Yamasaki H, and Trosko JE. Reduced gap junctional intercellular communication and altered biological effects in mouse osteoblast and rat liver oval cell lines transfected with dominant-negative connexin 43. Mol Carcinog 37: 192-201, 2003.
    • (2003) Mol Carcinog , vol.37 , pp. 192-201
    • Upham, B.L.1    Suzuki, J.2    Chen, G.3    Wang, Y.4    McCabe, L.R.5    Chang, C.C.6    Krutovskikh, V.A.7    Yamasaki, H.8    Trosko, J.E.9
  • 33
    • 15844394777 scopus 로고    scopus 로고
    • Gap junctional intercellular communication contributes hormonal responsiveness in osteoblastic networks
    • Vander Molen MA, Rubin CT, McLeod KJ, McCauley LK, and Donahue HJ. Gap junctional intercellular communication contributes hormonal responsiveness in osteoblastic networks. J Biol Chem 271: 12165-12171, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 12165-12171
    • Vander Molen, M.A.1    Rubin, C.T.2    McLeod, K.J.3    McCauley, L.K.4    Donahue, H.J.5
  • 34
    • 0027930471 scopus 로고
    • Hypophosphatasia and the role of alkaline phosphatase in skeletal mineralization
    • Whyte MP. Hypophosphatasia and the role of alkaline phosphatase in skeletal mineralization. Endocr Rev 15: 439-461, 1994.
    • (1994) Endocr Rev , vol.15 , pp. 439-461
    • Whyte, M.P.1
  • 35
    • 0033804637 scopus 로고    scopus 로고
    • Substrate deformation levels associated with routine physical activity are less stimulatory to bone cells relative to loading-induced oscillatory fluid flow
    • You J, Yellowley CE, Donahue HJ, Zhang Y, Chen Q, and Jacobs CR. Substrate deformation levels associated with routine physical activity are less stimulatory to bone cells relative to loading-induced oscillatory fluid flow. J Biomech Eng 122: 387-393, 2000.
    • (2000) J Biomech Eng , vol.122 , pp. 387-393
    • You, J.1    Yellowley, C.E.2    Donahue, H.J.3    Zhang, Y.4    Chen, Q.5    Jacobs, C.R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.