Modulation of angiogenesis by tissue inhibitor of metalloproteinase-4

Biochemical and Biophysical Research Communications

Volumn 345, Issue 1, 2006, Pages 523-529

  Fernández, Cecilia A ^a   Moses, Marsha A ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Angiogenesis; Endothelial cell; Matrix metalloproteinase; MMP; TIMP; Tissue inhibitor of metalloproteinase

Indexed keywords

METALLOPROTEINASE; METALLOPROTEINASE 4; TISSUE INHIBITOR OF METALLOPROTEINASE 4; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; CAPILLARY ENDOTHELIUM; CELL MIGRATION; CLONE; CONTROLLED STUDY; EMBRYO; ENDOTHELIUM CELL; ENZYME INHIBITION; ENZYME PURIFICATION; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PICHIA PASTORIS; PRIORITY JOURNAL;

ANIMALS; CATTLE; CELL PROLIFERATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; HUMANS; NEOVASCULARIZATION, PHYSIOLOGIC; TISSUE INHIBITOR OF METALLOPROTEINASES;

ANIMALIA; PICHIA PASTORIS;

EID: 33646409067     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.04.083     Document Type: Article

References (33)

1. Greene J., Wang M., Liu Y.E., Raymond L.A., Rosen C., and Shi Y.E. Molecular cloning and characterization of human tissue inhibitor of metalloproteinase 4. J. Biol. Chem. 271 (1996) 30375-30380
2. Liu Y.E., Wang M., Greene J., Su J., Ullrich S., Li H., Sheng S., Alexander P., Sang Q.A., and Shi Y.E. Preparation and characterization of recombinant tissue inhibitor of metalloproteinase 4 (TIMP-4). J. Biol. Chem. 272 (1997) 20479-20483
3. Stratmann B., Farr M., and Tschesche H. Characterization of C-terminally truncated human tissue inhibitor of metalloproteinases-4 expressed in Pichia pastoris. Biol. Chem. 382 (2001) 987-991
4. Roy R., Wewer U.M., Zurakowski D., Pories S.E., and Moses M.A. ADAM 12 cleaves extracellular matrix proteins and correlates with cancer status and stage. J. Biol. Chem. 279 (2004) 51323-51330
5. Lee M.H., Rapti M., and Murphy G. Total conversion of tissue inhibitor of metalloproteinase (TIMP) for specific metalloproteinase targeting: fine-tuning TIMP-4 for optimal inhibition of tumor necrosis factor-{alpha}- converting enzyme. J. Biol. Chem. 280 (2005) 15967-15975
6. Bigg H.F., Shi Y.E., Liu Y.E., Steffensen B., and Overall C.M. Specific, high affinity binding of tissue inhibitor of metalloproteinases-4 (TIMP-4) to the COOH-terminal hemopexin-like domain of human gelatinase A. TIMP-4 binds progelatinase A and the COOH- terminal domain in a similar manner to TIMP-2. J. Biol. Chem. 272 (1997) 15496-15500
7. Bigg H.F., Morrison C.J., Butler G.S., Bogoyevitch M.A., Wang Z., Soloway P.D., and Overall C.M. Tissue inhibitor of metalloproteinases-4 inhibits but does not support the activation of gelatinase A via efficient inhibition of membrane type 1-matrix metalloproteinase. Cancer Res. 61 (2001) 3610-3618
8. Murphy A.N., Unsworth E.J., and Stetler-Stevenson W.G. Tissue inhibitor of metalloproteinases-2 inhibits bFGF-induced human microvascular endothelial cell proliferation. J. Cell. Physiol. 157 (1993) 351-358
9. Fernandez C.A., Butterfield C., Jackson G., and Moses M.A. Structural and functional uncoupling of the enzymatic and angiogenic inhibitory activities of tissue inhibitor of metalloproteinase-2 (TIMP-2): loop 6 is a novel angiogenesis inhibitor. J. Biol. Chem. 278 (2003) 40989-40995
10. Seo D.W., Li H., Guedez L., Wingfield P.T., Diaz T., Salloum R., Wei B.Y., and Stetler-Stevenson W.G. TIMP-2 mediated inhibition of angiogenesis: an MMP-independent mechanism. Cell 114 (2003) 171-180
11. Wang M., Liu Y.E., Greene J., Sheng S., Fuchs A., Rosen E.M., and Shi Y.E. Inhibition of tumor growth and metastasis of human breast cancer cells transfected with tissue inhibitor of metalloproteinase 4. Oncogene 14 (1997) 2767-2774
12. Jiang Y., Wang M., Celiker M.Y., Liu Y.E., Sang Q.X., Goldberg I.D., and Shi Y.E. Stimulation of mammary tumorigenesis by systemic tissue inhibitor of matrix metalloproteinase 4 gene delivery. Cancer Res. 61 (2001) 2365-2370
13. Celiker M.Y., Wang M., Atsidaftos E., Liu X., Liu Y.E., Jiang Y., Valderrama E., Goldberg I.D., and Shi Y.E. Inhibition of Wilms' tumor growth by intramuscular administration of tissue inhibitor of metalloproteinases-4 plasmid DNA. Oncogene 20 (2001) 4337-4343
14. Fernandez C.A., Yan L., Louis G., Yang J., Kutok J.L., and Moses M.A. The matrix metalloproteinase- 9/neutrophil gelatinase-associated lipocalin complex plays a role in breast tumor growth and is present in the urine of breast cancer patients. Clin. Cancer Res. 11 (2005) 5390-5395
15. Moses M.A., Sudhalter J., and Langer R. Identification of an inhibitor of neovascularization from cartilage. Science 248 (1990) 1408-1410
16. Moses M.A., Sudhalter J., and Langer R. Isolation and characterization of an inhibitor of neovascularization from scapular chondrocytes. J. Cell. Biol. 119 (1992) 475-482
17. O'Reilly M.S., Holmgren L., Shing Y., Chen C., Rosenthal R.A., Moses M., Lane W.S., Cao Y., Sage E.H., and Folkman J. Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma [see comments]. Cell 79 (1994) 315-328
18. Moses M.A., Wiederschain D., Wu I., Fernandez C.A., Ghazizadeh V., Lane W.S., Flynn E., Sytkowski A., Tao T., and Langer R. Troponin I is present in human cartilage and inhibits angiogenesis. Proc. Natl. Acad. Sci. USA 96 (1999) 2645-2650
19. Connolly D.T., Knight M.B., Harakas N.K., Wittwer A.J., and Feder J. Determination of the number of endothelial cells in culture using an acid phosphatase assay. Anal. Biochem. 152 (1986) 136-140
20. Fang J., Shing Y., Wiederschain D., Yan L., Butterfield C., Jackson G., Harper J., Tamvakopoulos G., and Moses M.A. Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumor model. Proc. Natl. Acad. Sci. USA 97 (2000) 3884-3889
21. Mujumdar V.S., and Tyagi S.C. Temporal regulation of extracellular matrix components in transition from compensatory hypertrophy to decompensatory heart failure. J. Hypertens 17 (1999) 261-270
22. Tummalapalli C.M., Heath B.J., and Tyagi S.C. Tissue inhibitor of metalloproteinase-4 instigates poptosis in transformed cardiac fibroblasts. J. Cell. Biochem. 80 (2001) 512-521
23. Radomski A., Jurasz P., Sanders E.J., Overall C.M., Bigg H.F., Edwards D.R., and Radomski M.W. Identification, regulation and role of tissue inhibitor of metalloproteinases-4 (TIMP-4) in human platelets. Br. J. Pharmacol. 137 (2002) 1330-1338
24. Handsley M.M., and Edwards D.R. Metalloproteinases and their inhibitors in tumor angiogenesis. Int. J. Cancer 115 (2005) 849-860
25. Hayakawa T., Yamashita K., Tanzawa K., Uchijima E., and Iwata K. Growth-promoting activity of tissue inhibitor of metalloproteinases-1 (TIMP-1) for a wide range of cells. A possible new growth factor in serum. FEBS Lett. 298 (1992) 29-32
26. Anand-Apte B., Pepper M.S., Voest E., Montesano R., Olsen B., Murphy G., Apte S.S., and Zetter B. Inhibition of angiogenesis by tissue inhibitor of metalloproteinase-3. Invest. Ophthalmol. Vis. Sci. 38 (1997) 817-823
27. Qi J.H., Ebrahem Q., Moore N., Murphy G., Claesson-Welsh L., Bond M., Baker A., and Anand-Apte B. A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2. Nat. Med. 9 (2003) 407-415
28. Rhee J.S., and Coussens L.M. RECKing MMP function: implications for cancer development. Trends Cell Biol. 12 (2002) 209-211
29. Lafleur M.A., Handsley M.M., Knauper V., Murphy G., and Edwards D.R. Endothelial tubulogenesis within fibrin gels specifically requires the activity of membrane-type-matrix metalloproteinases (MT-MMPs). J. Cell Sci. 115 (2002) 3427-3438
30. Ma D.H., Zhang F., Shi W., Yao J.Y., Hsiao C.H., Wu H.C., Kim W.S., Hao Y.X., Hwang D.G., Chen J.K., and Tsai R.J. Expression of tissue inhibitor of metalloproteinase-4 in normal human corneal cells and experimental corneal neovascularization. Ophthalmic Res. 35 (2003) 199-207
31. Moses M.A. The regulation of neovascularization of matrix metalloproteinases and their inhibitors. Stem Cells 15 (1997) 180-189
32. Moses M.A., Harper J., and Fernandez C.A. A role for antiangiogenic therapy in breast cancer. Curr. Oncol. Rep. 6 (2004) 42-48
33. Roy R., Zhang B., and Moses M.A. Making the cut: protease-mediated regulation of angiogenesis. Exp. Cell Res. 312 (2006) 608-622