Total conversion of tissue inhibitor of metalloproteinase (TIMP) for specific metalloproteinase targeting: Fine-tuning TIMP-4 for optimal inhibition of tumor necrosis factor-α-converting enzyme

Journal of Biological Chemistry

Volumn 280, Issue 16, 2005, Pages 15967-15975

  Lee, Meng Huee ^a   Rapti, Magdalini ^a   Murphy, Gillian ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIODIVERSITY; DISEASES; ENZYME INHIBITION; ENZYME KINETICS; HEALTH CARE; MUTAGENESIS; TUMORS;

CHEMICAL RESIDUES; MAMMALS; METALLOPROTEINS; TISSUE INHIBITOR;

TISSUE;

GLYCINE; LEUCINE; PHENYLALANINE; PROLINE; TISSUE INHIBITOR OF METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TISSUE INHIBITOR OF METALLOPROTEINASE 3; TISSUE INHIBITOR OF METALLOPROTEINASE 4; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; INTERMETHOD COMPARISON; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN TARGETING; SITE DIRECTED MUTAGENESIS;

ADAM PROTEINS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; HUMANS; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; TISSUE INHIBITOR OF METALLOPROTEINASES;

MAMMALIA;

EID: 18144384702     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M500897200     Document Type: Article

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