Analysis of FimX, a phosphodiesterase that governs twitching motility in Pseudomonas aeruginosa

Molecular Microbiology

Volumn 60, Issue 4, 2006, Pages 1026-1043

  Kazmierczak, Barbara I ^a   Lebron, Maria B ^a   Murray, Thomas S ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CC3396 PROTEIN; CYCLIC DIMERIC GUANOSINE MONOPHOSPHATE; DIGUANYLATE CYCLASE; FIMX PROTEIN; FUNGAL ENZYME; GUANOSINE PHOSPHATE; GUANOSINE TRIPHOSPHATE; PHOSPHODIESTERASE; RFP PROTEIN; UNCLASSIFIED DRUG;

ADOLESCENT; ANIMAL MODEL; ARTICLE; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; BACTERIUM PILUS; BIOFILM; CAULOBACTER CRESCENTUS; CELL SURFACE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME ANALYSIS; FEMALE; HUMAN; HUMAN CELL; MOUSE; MUTATION; NONHUMAN; PHENOTYPE; PNEUMONIA; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PSEUDOMONAS AERUGINOSA; TRANSMISSION ELECTRON MICROSCOPY; TWITCHING MOTILITY; TYPE IV PILUS;

ANIMALS; BACTERIAL PROTEINS; CELL MOVEMENT; CYCLIC GMP; FEMALE; FIMBRIAE, BACTERIAL; HELA CELLS; HUMANS; MICE; MICE, INBRED C57BL; PHOSPHORIC DIESTER HYDROLASES; PHOSPHORUS-OXYGEN LYASES; PNEUMONIA, BACTERIAL; POINT MUTATION; PROTEIN STRUCTURE, TERTIARY; PSEUDOMONAS AERUGINOSA; SEQUENCE DELETION; VIRULENCE;

ANIMALIA; BACTERIA (MICROORGANISMS); CAULOBACTER VIBRIOIDES; MURINAE; PSEUDOMONAS AERUGINOSA;

EID: 33646397872     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2006.05156.x     Document Type: Article

References (60)

1. Aldridge P Jenal U 1999 Cell cycle-dependent degradation of a flagellar motor component requires a novel-type response regulator Mol Microbiol 32 379 391
2. Ausmees N Jonsson H Hoglund S Ljunggren H-G Lindberg M 1999 Structural and putative regulatory genes involved in cellulose synthesis in Rhizobium leguminosarum bv. trifolii Microbiology 145 1253 1262
3. Bobrov AG Kirillina O Perry RD 2005 The phosphodiesterase activity of the HmsP EAL domain is required for negative regulation of biofilm formation in Yersinia pestis FEMS Microbiol Lett 247 123 130
4. Bradley DE 1980 A function of Pseudomonas aeruginosa PAO pili: twitching motility Can J Microbiol 26 146 154
5. Brookman JL Stott AJ Cheeseman PJ Burns NR Adams SE Kingsman AJ Gull K 1995 An immunological analysis of Ty1 virus-like particle structure Virology 207 59 67
6. Chan C Paul R Samoray D Amiot NC Giese B Jenal U Schirmer T 2004 Structural basis of activity and allosteric control of diguanylate cyclase Proc Natl Acad Sci USA 101 17084 17089
7. Chenna R Sugawara H Koike T Lopez R Gibson TJ Higgins DG Thompson JD 2003 Multiple sequence alignment with the Clustal series of programs Nucleic Acids Res 31 3497 3500
8. Chi E Mehl T Nunn D Lory S 1991 Interaction of Pseudomonas aeruginosa with A549 pneumocyte cells Infect Immun 59 822 828
9. Christen M Christen B Folcher M Schauerte A Jenal U 2005 Identification and characterization of a cyclic di-GMP specific phosphodiesterase and its allosteric control by GTP J Biol Chem 280 30829 30837
10. Comolli J Waite L Mostov K Engel JN 1999a The interaction of Pseudomonas aeruginosa pili and asialo-GM1 stimulates epithelial cell cytotoxicity and bacterial internalization Infect Immun 67 3207 3214
11. Comolli J Hauser A Waite L Whitchurch C Mattick J Engel J 1999b PilU and PilT are required for cytotoxicity and virulence of Pseudomonas aeruginosa Infect Immun 67 3625 3630
12. D'Argenio DA Calfee MW Rainey PB Pesci EC 2002 Autolysis and autoaggregation in Pseudomonas aeruginosa colony morphology mutants J Bacteriol 184 6481 6489
13. De Medicis E Paquette J Gauthier J-J Shapcott D 1986 Magnesium and manganese contact of halophilic bacteria Appl Environ Microbiol 52 567 573
14. Doig P Todd T Sastry PA Lee KK Hodges RS Paranchych W Irvin RT 1988 Role of pili in adhesion of Pseudomonas aeruginosa to human respiratory epithelial cells Infect Immun 56 1641 1646
15. Finck-Barbancon V Goranson J Zhu L Sawa T Wiener-Kronish JP Fleiszig SMJ et al. 1997 ExoU expression by Pseudomonas aeruginosa correlates with acute cytotoxicity and epithelial injury Mol Microbiol 25 547 557
16. Francis SH Turko IV Grimes KA Corbin JD 2000 Histidine-607 and histidine-643 provide important interactions for metal support of catalysis in phosphodiesterase-5 Biochemistry 39 9591 9596
17. Frank DW 1997 The exoenzyme S regulon of Pseudomonas aeruginosa Mol Microbiol 4 621 629
18. Garrity-Ryan L Kazmierczak B Kowal R Comolli J Hauser A Engel J 2000 The arginine finger domain of ExoT is required for actin cytoskeleton disruption and inhibition of internalization of Pseudomonas aeruginosa by epithelial cells and macrophages Infect Immun 68 7100 7113
19. Goodman AL Kulasekara BR Rietsch A Boyd D Smith RS Lory S 2004 A signaling network reciprocally regulates genes associated with acute infection and chronic persistence in Pseudomonas aeruginosa Develop Cell 7 745 754
20. Hauser AR Kang PJ Engel J 1998 PepA, a novel secreted protein of Pseudomonas aeruginosa, is necessary for cytotoxicity and virulence Mol Microbiol 27 807 818
21. Hoang TT Karkhoff-Schweizer RR Kutchma AJ Schweizer HP 1998 A broad-host-range Flp-FRT recombination system for site-specific excision of chromosomally-located DNA sequences: application for isolation of unmarked Pseudomonas aeruginosa mutants Gene 212 77 86
22. Hoch JA Silhavy TJ eds. 1995 Two-Component Signal Transduction Washington, DC American Society for Microbiology Press
23. Huang B Whitchurch CB Croft L Beatson SA Mattick JS 2000 A minimal tiling path cosmid library for functional analysis of the Pseudomonas aeruginosa PAO1 genome Microb Comp Genomics 5 189 203
24. Huang B Whitchurch CB Mattick JS 2003 FimX, a multidomain protein connecting environmental signals to twitching motility in Pseudomonas aeruginosa J Bacteriol 185 7068 7076
25. Kang PJ Hauser AR Apodaca G Fleiszig S Wiener-Kronish J Mostov K Engel JN 1997 Identification of Pseudomonas aeruginosa genes required for epithelial cell injury Mol Microbiol 24 1249 1262
26. Kelly NM Kluftinger JL Pasloske BL Paranchych W Hancock RE 1989 Pseudomonas aeruginosa pili as ligands for nonsopsonic phagocytosis by fibronectin-stimulated macrophages Infect Immun 57 3841 3845
27. Kirillina O Fetherston JD Bobrov AG Abney J Perry RD 2004 HmsP, a putative phosphodiesterase, and HmsT, a putative diguanylate cyclase, control Hms-dependent biofilm formation in Yersinia pestis Mol Microbiol 54 75 88
28. Klausen M Aaes-Jorgensen A Molin S Tolker-Nielsen T 2003a Involvement of bacterial migration in the development of complex multicellular structures in Pseudomonas aeruginosa biofilms Mol Microbiol 50 61 68
29. Klausen M Heydorn A Ragas P Lambertsen L Aaes-Jorgensen A Molin S Tolker-Nielsen T 2003b Biofilm formation by Pseudomonas aeruginosa wild type, flagella and type IV pili mutants Mol Microbiol 48 1511 1524
30. Kulesekara H Lee VT Brencic A Liberati N Urbach J Miyata S et al. 2006 Analysis of Pseudomonas aeruginosa diguanylate cyclases and phosphodiesterases reveals a role for bis-(3′-5′)-cyclic-GMP in virulence Proc Natl Acad Sci USA 103 2839 2844
31. Laskowski MA Osborn E Kazmierczak BI 2004 A novel sensor kinase-response regulator hybrid regulates Type III secretion and is required for virulence in Pseudomonas aeruginosa Mol Microbiol 54 1090 1103
32. Liu PV 1966 The roles of various fractions of Pseudomonas aeruginosa in its pathogenesis: identity of the lethal toxins produced in vitro and in vivo J Infect Dis 116 481 489
33. Mattick JS 2002 Type IV pili and twitching motility Annu Rev Microbiol 56 289 314
34. Mattick JS Bills MM Anderson BJ Dalrymple B Mott MR Egerton JR 1987 Morphogenetic expression of Bacteroides nodosus fimbriae in Pseudomonas aeruginosa J Bacteriol 169 33 41
35. Merz AJ So M Sheetz MP 2000 Pilus retraction powers bacterial twitching motility Nature 407 98 102
36. Nicas TI Iglewski BH 1984 Isolation and characterization of transposon-induced mutants of Pseudomonas aeruginosa deficient in production of exoenzyme S Infect Immun 45 470 474
37. O'Toole GA Kolter R 1998 Flagellar and twitching motility are necessary for Pseudomonas aeruginosa biofilm development Mol Microbiol 30 295 304
38. Paul R Weiser S Amiot NC Chan C Schirmer T Giese B Jenal U 2004 Cell cycle-dependent dynamic localization of a bacterial response regulator with a novel di-guanylate cyclase output domain Genes Dev 18 715 727
39. Romling U Gomelsky M Galperin MY 2005 C-di-GMP: the dawning of a novel bacterial signalling system Mol Microbiol 57 629 639
40. Salyers AA Whitt DD (eds) 2002 Bacterial Pathogenesis: A Molecular Approach Washington, DC American Society for Microbiology Press
41. Sambrook J Fritsch EF Maniatis T 1989 Molecular Cloning: A Laboratory Manual Cold Spring Harbor, NY Cold Spring Harbor Laboratory Press
42. Sastry PA Finlay BB Pasloske BL Parachych W Pearlstone JR Smillie LB 1985 Comparative studies of the amino acid and nucleotide sequences of pilin derived from Pseudomonas aeruginosa PAK and PAO J Bacteriol 164 571 577
43. Sato H Frank DW Hillard CJ Feix JB Pankhaniya RR Moriyama K et al. 2003 The mechanism of action of the Pseudomonas aeruginosa encoded type III cytotoxin, ExoU EMBO J 22 2959 2969
44. Schmidt AJ Ryjenkov DA Gomelsky M 2005 The ubiquitous protein domain EAL is a cyclic diguanylate-specific phosphodiesterase: enzymatically active and inactive EAL domains J Bacteriol 187 4774 4781
45. Schweizer HP Hoang TT 1995 An improved system for gene replacement and xylE fusion analysis in Pseudomonas aeruginosa Gene 158 15 22
46. Simm R Morr M Kader A Nimtz M Romling U 2004 GGDEF and EAL domains inversely regulate cyclic di-GMP levels and transition from sessility to motility Mol Microbiol 53 1123 1134
47. Simon R Priefer U Puhler A 1983 A broad host range mobilization system for in vivo genetic engineering: transposon mutagenesis in gram negative bacteria Biotechnology 1 784 791
48. Singh PK Schaefer AL Parsek MR Moninger TO Welsh MJ Greenberg EP 2000 Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms Nature 407 762 764
49. Speert DP Loh BA Cabral DA Salit IE 1986 Nonopsonic phagocytosis of nonmucoid Pseudomonas aeruginosa by human neutrophils and monocyte-derived macrophages is correlated with bacterial piliation and hydrophobicity Infect Immun 53 207 212
50. Spiers AJ Kahn SG Bohannon J Travisano M Rainey PB 2002 Adaptive divergence in experimental populations of Pseudomonas fluorescens. I. Genetic and phenotypic bases of wrinkly spreader fitness Genetics 161 33 46
51. Stover C Pham X Erwin A Mizoguchi S Warrener P Hickey M et al. 2000 Complete genome sequence of Pseudomonas aeruginosa PA01, an opportunistic pathogen Nature 406 959 964
52. Sundin C Wolfgang M Lory S Forsberg A Frithz-Lindsten E 2002 Type IV pili are not specifically required for contact dependent translocation of exoenzymes by Pseudomonas aeruginosa Microb Pathog 33 265 277
53. Tal R Wong HC Calhoon R Gelfand D Fear AL Volman G et al. 1998 Three cdg operons control cellular turnover of cyclic di-GMP in Acetobacter xylinum: genetic organization and occurrence of conserved domains in isoenzymes J Bacteriol 180 4416 4425
54. Vallet I Olson JW Lory S Lazdunski A Filloux A 2001 The chaperone/usher pathways of Pseudomonas aeruginosa: identification of fimbrial gene clusters (cup) and their involvement in biofilm formation Proc Natl Acad Sci USA 98 6911 6916
55. Watson AA Alm RA Mattick JS 1996 Construction of improved vectors for protein production in Pseudomonas aeruginosa Gene 172 163 164
56. Whitchurch CB Leech AJ Young MD Kennedy D Sargent JL Bertrand JJ et al. 2004 Characterization of a complex chemosensory signal transduction system which controls twitching motility in Pseudomonas aeruginosa Mol Microbiol 52 873 893
57. Whitchurch CB Beatson SA Comolli JC Jakobsen T Sargent JL Bertrand JJ et al. 2005 Pseudomonas aeruginosa fimL regulates multiple virulence functions by intersecting with Vfr-modulated pathways Mol Microbiol 55 1357 1378
58. Woods DE Straus DC Johanson WG Berry VK Bass JA 1980 Role of pili in adherence of Pseudomonas aeruginosa to mammalian buccal epithelial cells Infect Immun 29 1146 1151
59. Zhulin IB Taylor BL 1997 PAS domain S-boxes in archaea, bacteria and sensors for oxygen and redox Trends Biochem Sci 22 331 333
60. Zogay X Nimtz M Rohde M Bokranz W Romling U 2001 The multicellular morphotypes of Salmonella typhimurium and Escherichia coli produce cellulose as the second component of the extracellular matrix Mol Microbiol 39 1452 1463