Accurate product ion mass spectra of galanthamine derivatives [2]

Journal of Mass Spectrometry

Volumn 41, Issue 4, 2006, Pages 544-548

  Jegorov, A ^b   Buchta, M ^b   Sedmera, P ^a   Kuzma, M ^a   Havlicek, V ^a  

^a INSTITUTE OF MICROBIOLOGY   (Czech Republic)

^b TEVA PHARMACEUTICALS   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID; BROMINE DERIVATIVE; GALANTAMINE;

DRUG STRUCTURE; FRAGMENTATION REACTION; IONIZATION; LETTER; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL;

ALGORITHMS; GALANTAMINE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 33646372198     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.1015     Document Type: Letter

References (16)

1. Jin Z. Amaryllidaceae and Scletium alkaloids. Nat. Prod. Rep. 2005; 22: 111.
2. Raskind MA. Update on Alzheimer drugs (Galanthamine). Neurologist 2003; 9: 235.
3. Farlow MR. Clinical pharmacokinetic of galantamine. Clin. Pharmacokinet. 2003; 42: 1383.
4. Sener B, Orhan I, Satayvivad J. Antimalarial activity screening of some alkaloids and the plant extracts from Amaryllidaceae. Phytoter. Res. 2003; 17: 1220.
5. Bores GM, Kosley RW Jr Galanthamine derivatives for the treatment of Alzheimer's disease. Drugs Future 1996; 21: 621.
6. Lamirault L, Guillou C, Thal C, Simon H. (-)-9-Dehydrogalanthaminium bromide, a new cholinesterase inhibitor, enhances place and object recognition memory in young and old rats. Neurobiol. Learn. Mem. 2003; 80: 113.
7. Razakov R, Bochkarev VN, Abduazimov KhA, Vul'fson NS, Yunusov SYu. A mass spectrometric investigation of alkaloids of the galanthamine type. Khim. Prir. Soedin. 1969; 5: 280.
8. Rivero N, Gomez M, Medina JD. Search for bioactive alkaloids in Hymenocallis species. Pharmaceut. Biol. 2004; 42: 280.
9. Kreh M, Matusch R, Witte L. Capillary gas chromatography-mass spectrometry of Amaryllidaceae alkaloids. Phytochemistry 1995; 38: 773.
10. Novikova IYu, Tulaganov AA. Physicochemical methods for the analysis of galanthamine (Review). Pharm. Chem. J. 2002; 36: 623.
11. Kreh M, Matusch R, Witte L. Capillary gas chromatography-mass spectrometry of amaryllidaceae alkaloids. Phytochemistry 1995; 38: 773.
12. Christov R, Bankova V, Elenkov I, Handjieva N, Spassov S, Popov SS. Stereo effects in the chemical ionization mass spectrometry of galanthamine epimers. Eur. Mass Spectrom. 1999; 5: 77.
13. Ingkaninan K, de Best CM, van der Heijden R, Hofte AJP, Karabatak B, Irth H, Tjaden UR, van der Greef J, Verpoorte R. High-performance liquid chromatography with on-line coupled UV, mass spectrometric and biochemical detection for identification of acetylcholinesterase inhibitors from natural products. J. Chromatogr., A 2000; 72: 61.
14. Verhaeghe T, Diels L, de Vries R, de Meulder M, de Jong J. Development and validation of a liquid chromatographic-tandem mass spectrometric method for the determination of galanthamine in human heparinised plasma. J. Chromatogr., B 2003; 89: 337.
15. Mannens GSJ, Snel CAW, Hendrickx J, Verhaeghe T, le Jeune L, Bode W, van Beijsterveldt L, Lavrijsen K, Leempoels J, van Orselaer N, van Peer A, Meuldermans W. The metabolism and excretion of galanthamine in rats, dogs, and humans. Drug Metab. Dispos. 2002; 30: 553.
16. Visky D, Jimidar I, van Ael W, Vennekens T, Redlich D, de Smet M. Capillary electrophoresis-mass spectrometry in impurity profiling of pharmaceutical products. Electrophoresis 2005; 26: 1541.