Antimalarial Activity Screening of Some Alkaloids and the Plant Extracts from Amaryllidaceae

Phytotherapy Research

Volumn 17, Issue 10, 2003, Pages 1220-1223

  Şener, Bilge ^a   Orhan, Ilkay ^a   Satayavivad, Jutamad ^b  

^a GAZI UNIVERSITY   (Turkey)

^b CHULABHORN RESEARCH INSTITUTE   (Thailand)

Author keywords

Alkaloid; Amaryllidaceae; Antimalarial activity; Falciparum; Plasmodium

Indexed keywords

6 HYDROXYHAEMANTHAMINE; ALKALOID DERIVATIVE; CRININE; GALANTAMINE; HAEMANTHAMINE; LEUCOJUM AESTIVUM EXTRACT; LYCORINE; NARCISSUS TAZETTA EXTRACT; PANCRATIUM MARITIMUM EXTRACT; TAZETTINE; UNCLASSIFIED DRUG;

AMARYLLIDACEAE; ANTIMALARIAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG ISOLATION; DRUG POTENCY; DRUG SCREENING; DRUG SENSITIVITY; HIGH THROUGHPUT SCREENING; LEUCOJUN AESTIVUM; MEDICINAL PLANT; NARCISSUS TAZETTA; NONHUMAN; PANCRATIUM MARITIMUM; PLANT GROWTH; PLASMODIUM FALCIPARUM; TURKEY (REPUBLIC);

ALKALOIDS; ANGIOSPERMS; ANIMALS; ANTIMALARIALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MALARIA, FALCIPARUM; MEDICINE, TRADITIONAL; PARASITIC SENSITIVITY TESTS; PHYTOTHERAPY; PLANT EXTRACTS; PLASMODIUM FALCIPARUM; TURKEY;

AMARYLLIDACEAE; LEUCOJUM; LEUCOJUM AESTIVUM; NARCISSUS; NARCISSUS TAZETTA; PANCRATIUM; PLASMODIUM FALCIPARUM;

EID: 0347987011     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.1346     Document Type: Article

References (13)

1. Cakici I, Ulug HY, Inci S, et al. 1997. Antinociceptive effect of some Amaryllidaceae plants in mice. J Pharm Pharmacol 49: 828-830.
2. Campbell WE, Nair JJ, Gammon DW, et al. 1998. Cytotoxic and antimalarial alkaloids from Brunsvigia littoralis. Planta Med 64: 91-93.
3. Citoglu G, Tanker M, Gumusel B. 1998. Antiinflammatory effects of lycorine and haemanthidine. Phytotherapy Res 12: 2005-2006.
4. Cordell GA, Angerhofer CK, Pezzuto JM. 1994. Recent studies on cytotoxic, anti-HIV and antimalarial agents from plants. Pure & Appl Chem 66: 2283-2286.
5. Davis PH, Cullen J. 1984. Flora of Turkey and the East Aegean IslandsVol. 8. Edinburgh University Press: Edinburgh; 365-372.
6. Fennel CW, van Staden J. 2001. Crinum species in traditional and modern medicine. J Ethnopharmacol 78: 15-26.
7. Lambros C, Vanderberg JP. 1979. Antimalarial activity screening methods for natural products. J Parasitol 65: 418-424.
8. Lewis JR. 1990. Amaryllidaceae alkaloids. Nat Prod Rep 7: 549-556.
9. Montanha JA, Amoros M, Boustie J, Girre L. 1995. Anti-herpes virus activity of aporphine alkaloids. Planta Med 61: 419-424.
10. Rhee IK, van de Meent M, Ingkaninas K, Verpoorte R. 2001. Screening for acetylcholinesterase inhibitors from Amaryllidaceae using silica gel thin-layer chromatography in combination with bioactivity staining. J. Chromatog. A 915, 217-223.
11. Schmeda-Hirschmann G, Astudillo L, Bastida J, Viladomat F, Codina C. 2000. DNA binding activity of Amaryllidaceae alkaloids. Bol Soc Chil Quim 45, 515-518.
12. Sener B, Konukol S, Muhtar F. 1998. New alkaloids and biological activities of Turkish Amaryllidaceae plants. In: New Trends in Natural Product Chemistry, Eds. Rahman, A. -ur, and Choudhary, M. I., Harwood Academic Publishers, Amsterdam 187-195.
13. Yui S, Mikami M, Kitahara M, Yamazaki M. 1998. The inhibitory effect of lycorine on tumor cell apoptosis induced by polymorphonuclear leukocyte-derived calprotectin. Immunopharmacol. 40, 151-162.