Candida albicans Spt23p controls the expression of the Ole1p Δ9 fatty acid desaturase and regulates unsaturated fatty acid biosynthesis

Journal of Biological Chemistry

Volumn 281, Issue 11, 2006, Pages 7030-7039

  Oh, Chan Seok ^a   Martin, Charles E ^a,b  

^a RUTGERS UNIVERSITY   (United States)

^b Nelson Laboratories   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; BIOSYNTHESIS; CELL MEMBRANES; ENZYME KINETICS; FATTY ACIDS; POLYPEPTIDES;

CANDIDA ALBICANS SPT23P; DESATURASE; ENDOPLASMIC RETICULUM (ER); SACCHAROMYCES CEREVISIAE;

ENZYMES;

ACYL COENZYME A DESATURASE; GENOMIC DNA; UNSATURATED FATTY ACID; BETA GALACTOSIDASE; DELTA 9 FATTY ACID DESATURASE; DELTA-9 FATTY ACID DESATURASE; EPITOPE; FATTY ACID; GLUCOSE; LIPID; MALTOSE; PRIMER DNA; RNA; SACCHAROMYCES CEREVISIAE PROTEIN; SPT23 PROTEIN, S CEREVISIAE; TRANSACTIVATOR PROTEIN;

ARTICLE; BACTERIAL GENE; CANDIDA ALBICANS; CONTROLLED STUDY; DNA SEQUENCE; ENDOPLASMIC RETICULUM; FATTY ACID METABOLISM; GENE SEQUENCE; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES; SPT23P GENE; AMINO ACID SEQUENCE; BIOLOGICAL MODEL; CELL MEMBRANE; CELL PROLIFERATION; CHEMISTRY; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PLASMID; POLYMERASE CHAIN REACTION; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SACCHAROMYCES CEREVISIAE; TIME; WESTERN BLOTTING;

CANDIDA; CANDIDA ALBICANS; FUNGI; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

AMINO ACID SEQUENCE; BASE SEQUENCE; BETA-GALACTOSIDASE; BLOTTING, NORTHERN; BLOTTING, WESTERN; CANDIDA ALBICANS; CELL MEMBRANE; CELL PROLIFERATION; CLONING, MOLECULAR; DNA PRIMERS; ENDOPLASMIC RETICULUM; EPITOPES; FATTY ACID DESATURASES; FATTY ACIDS; GLUCOSE; LIPIDS; MALTOSE; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; PLASMIDS; POLYMERASE CHAIN REACTION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RNA; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TIME FACTORS; TRANS-ACTIVATORS;

EID: 33646368401     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M510746200     Document Type: Article

References (31)

1. Bossie, M. A., and Martin, C. E. (1989) J. Bacteriol. 171, 6409-6413
2. Pugh, E. L., and Kates, M. (1975) Biochim. Biophys. Acta 380, 442-453
3. Pugh, E. L., and Kates, M. (1977) J. Biol. Chem. 252, 68-73
4. Zhang, S., Skalsky, Y., and Garfinkel, D. J. (1999) Genetics 151, 473-483
5. Chellappa, R., Kandasamy, P., Oh, C. S., Jiang, Y., Vemula, M., and Martin, C. E. (2001) J. Biol. Chem. 276, 43548-43556
6. Kandasamy, P., Vemula, M., Oh, C. S., Chellappa, R., and Martin, C. E. (2004) J. Biol. Chem. 279, 36586-36592
7. Hoppe, T., Matuschewski, K., Rape, M., Schlenker, S., Ulrich, H. D., and Jentsch, S. (2000) Cell 102, 577-586
8. Tocher, D. R., Leaver, M. J., and Hodgson, P. A. (1998) Prog. Lipid Res. 37, 73-117
9. Michaelson, L. V., Lazarus, C. M., Griffiths, G., Napier, J. A., and Stobart, A. K. (1998) J. Biol. Chem. 273, 19055-19059
10. Sakuradani, E., Kobayashi, M., Ashikari, T., and Shimizu, S. (1999) Eur. J. Biochem. 261, 812-820
11. Sakuradani, E., Kobayashi, M., and Shimizu, S. (1999) Gene (Amst.) 238, 445-453
12. Vemula, M., Kandasamy, P., Oh, C. S., Chellappa, R., Gonzalez, C. I., and Martin, C. E. (2003) J. Biol. Chem. 278, 45269-45279
13. Wilson, R. B., Davis, D., and Mitchell, A. P. (1999) J. Bacteriol. 181, 1868-1874
14. Wilson, R. B., Davis, D., Enloe, B. M., and Mitchell, A. P. (2000) Yeast 16, 65-70
15. Gola, S., Martin, R., Walther, A., Dunkler, A., and Wendland, J. (2003) Yeast 20, 1339-1347
16. Choi, J. Y., Stukey, J., Hwang, S. Y., and Martin, C. E. (1996) J. Biol. Chem. 271, 3581-3589
17. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., and Struhl, K. (1987) Current Protocols in Molecular Biology, John Wiley and Sons, New York
18. Hampton, R. Y., and Rine, J. (1994) J. Cell Biol. 125, 299-312
19. Laemmli, U. K., Molbert, E., Showe, M., and Kellenberger, E. (1970) J. Mol. Biol. 49, 99-113
20. McDonough, V. M., Stukey, J. E., and Martin, C. E. (1992) J. Biol. Chem. 267, 5931-5936
21. Toke, D. A., and Martin, C. E. (1996) J. Biol. Chem. 271, 18413-18422
22. Bligh, E. G., and Dyer, W. J. (1959) Can. J. Biochem. Biophys. 37, 911-917
23. Folch, J., Lees, M., and Sloane Stanley, G. H. (1957) J. Biol. Chem. 226, 497-509
24. Backen, A. C., Broadbent, I. D., Fetherston, R. W., Rosamond, J. D., Schnell, N. F., and Stark, M. J. (2000) Yeast 16, 1121-1129
25. Cormack, B. P., Bertram, G., Egerton, M., Gow, N. A., Falkow, S., and Brown, A. J. (1997) Microbiology 143, 303-311
26. Geber, A., Williamson, P. R., Rex, J. H., Sweeney, E. C., and Bennett, J. E. (1992) J. Bacteriol. 174, 6992-6996
27. Krishnamurthy, S., Plaine, A., Albert, J., Prasad, T., Prasad, R., and Ernst, J. F. (2004) Microbiology 150, 1991-2003
28. Hedges, S. B., Blair, J. E., Venturi, M. L., and Shoe, J. L. (2004) BMC Evol. Biol. 4, 2-10
29. Stukey, J. E., McDonough, V. M., and Martin, C. E. (1989) J. Biol. Chem. 264, 16537-16544
30. Sudbery, P., Gow, N., and Berman, J. (2004) Trends Microbiol. 12, 317-324
31. Brown, A. J., Barelle, C. J., Budge, S., Duncan, J., Harris, S., Lee, P. R., Leng, P., Macaskill, S., Abdul Murad, A. M., Ramsdale, M., Wiltshire, C., Wishart, J. A., and Gow, N. A. (2000) Contrib. Microbiol. 5, 112-125