Identification of IEX-1 as a biomechanically controlled nuclear factor-κB target gene that inhibits cardiomyocyte hypertrophy

Circulation Research

Volumn 90, Issue 6, 2002, Pages 690-696

  De Keulenaer, Gilles W ^a   Wang, Yanlin ^a   Feng, Yajun ^a   Muangman, Suphi ^a   Yamamoto, Keiji ^a   Thompson, John F ^b   Turi, Thomas G ^b   Landschutz, Katherine ^b   Lee, Richard T ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Apoptosis; Biomechanical strain; Cardiomyocytes; Heart failure; Hypertrophy

Indexed keywords

ENDOTHELIN 1; GENE PRODUCT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; PHENYLEPHRINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BIOMECHANICS; CELL STIMULATION; CELL VIABILITY; CONTROLLED STUDY; GENE; GENE ACTIVATION; GENE OVEREXPRESSION; GENE TARGETING; GENE TRANSFER; HEART FAILURE; HEART HYPERTROPHY; HEART MUSCLE CELL; IEX 1 GENE; MECHANICAL STIMULATION; NONHUMAN; PRIORITY JOURNAL; RAT;

NON-PROGRAMMATIC;

ADENOVIRIDAE; ANIMALS; APOPTOSIS REGULATORY PROTEINS; CARDIOMEGALY; CELL SIZE; CELLS, CULTURED; GENE EXPRESSION REGULATION; GENETIC VECTORS; IMMEDIATE-EARLY PROTEINS; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; NEOPLASM PROTEINS; NF-KAPPA B; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TRANSFECTION;

EID: 0037023649     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000012922.40318.05     Document Type: Article

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