Angiotensin I-converting enzyme inhibitory activity of soy protein digest in a dynamic model system simulating the upper gastrointestinal tract

Journal of Food Science

Volumn 71, Issue 3, 2006, Pages

  Lo, Wendy M Y ^a   Farnworth, Edward R ^b   Li Chan, Eunice C Y ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b FOOD RESEARCH AND DEVELOPMENT CENTRE   (Canada)

Author keywords

Angiotensin I converting enzyme inhibitory activity; Dynamic model system; Heat treatment; Simulated gastrointestinal digestion; Soy protein

Indexed keywords

GLYCINE MAX;

EID: 33646350312     PISSN: 00221147     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2621.2006.tb15646.x     Document Type: Article

References (37)

1. Acharya KR, Sturrock ED, Riordan JF, Ehlers MRW. 2003. ACE revisited: a new target for structure-based drug design. Nature Rev Drug Disc 2:891-902.
2. Adler-Nissen J. 1979. Determination of the degree of hydrolysis of food protein hydrolysates by trinitrobenzenesulfonic acid. J Agric Food Chem 27:1256-62.
3. Ahn SW, Kim KM, Yu KW, Noh DO, Suh HJ. 2000. Isolation of angiotensin I converting enzyme inhibitory peptide from soybean hydrolysate. Food Sci Biotechnol 9:378-81.
4. Berrada N, Lemeland JF, Laroche G, Thouvenot P, Piaia M. 1991. Bifidobacterium from fermented milks: survival during the gastric transit. J Dairy Sci 74:403-13.
5. Chabance B, Marteau P, Rambaud JC, Migliore-Samour D, Boynard M, Perrotin P, Guillet R, Jollès P, Fiat AM. 1998. Casein peptide release and passage to the blood in humans during digestion of milk or yogurt. Biochimie 80:155-65.
6. Chen JR, Yang SC, Suetsuna K, Chao JCJ. 2004. Soybean protein-derived hydrolysate affects blood pressure in spontaneously hypertensive rats. J Food Biochem 28:61-73.
7. Cushman DW, Cheung HS. 1971. Spectrophotometric assay and properties of the angiotensin converting enzyme of rabbit lung. Biochem Pharmacol 20:1637-48.
8. Cushman DW, Ondetti MA, Gordon EM, Natarajan S, Karanewsky DS, Krapcho J, Petrillo EW 1987. Rational design and biochemical utility of specific inhibitors of angiotensin-converting enzyme. J Cardiovasc Pharmacol 10:517-30.
9. ExPASy. 2005. NiceZyme View of Enzyme: enzyme nomenclature database. Available from: http://ca.expasy.org/enzyme/. Accessed 2005 Aug 8.
10. Fruton JS. 1970. Pepsin. In: Boyer PD, editor. The Enzymes 3rd ed. v3. Peptide Bond Hydrolysis. New York: Academic Press, p 119-64.
11. Fujita H, Yoshikawa M. 1999. LKPNM: a prodrug-type ACE inhibitory peptide derived from fish protein. Immunopharmacology 44:123-7.
12. Garrett DA, Failla ML, Sarama RJ. 1999. Development of an in vitro digestion method to assess carotenoid bioavailability from meals. J Agric Food Chem 47:4301-9.
13. Golbitz P. 1995. Traditional soyfoods: processing and products. J Nutr 125:570S-2S.
14. Guyton AC, Hall JE. 1996. Dominant role of the kidneys in long-term regulation of arterial pressure and in hypertension. In: Textbook of medical physiology. 9th ed. Philadelphia, Pa.: W.B. Sanders Co. p 221-37.
15. Guyton AC, Hall JE. 2000. Secretory functions of the alimentary tract. In: Textbook of medical physiology. 10th ed. Philadelphia: WB. Sanders Co. p 738-53.
16. He J, Gu D, Wu X, Chen J, Duan X, Chen J, Whelton P. 2005. Effect of soybean protein on blood pressure: a randomized, controlled trial. Ann Intern Med 143:1-9.
17. Hernández-Ledesma B, Amigo L, Ramos M, Recio I. 2004. Angiotensin converting enzyme inhibitory activity in commercial fermented products. Formation of peptides under simulated gastrointestinal digestion. J Agric Food Chem 42:1504-10.
18. Izzo JL, Black HR. 2003. Approach to the management of hypertension. In: Izzo JL, Black HR, Goodfriend TL, Sowers JR, Weder AB, Appel LJ, Sheps SG, Sica DA, Vidt DG, editors. Hypertension primer. 3rd ed. Baltimore: Lippincott Williams & Wilkins. p 378-81.
19. Izzo JL, Black HR, Goodfriend TL, Sowers JR, Weder AB, Appel LJ, Sheps SG, Sica DA, Vidt DG, editors. 2003. Hypertension primer. 3rd ed. Baltimore, Md.: Lippincott Williams & Wilkins
20. Kannel WB, Wilson PWF. 2003. Cardiovascular risk factors and hypertension. In: Izzo JL, Black HR, Goodfriend TL, Sowers JR, Weder AB, Appel LJ, Sheps SG, Sica DA, Vidt DG, editors. Hypertension primer. 3rd ed. Baltimore, Md.: Lippincott Williams & Wilkins. p 235-8.
21. Kuba M, Tana C, Tawata S, Yasuda M. 2005. Production of angiotensin I-converting enzyme inhibitory peptides from soybean protein with Monascus purpureus acid proteinase. Proc Biochem 40:2191-6.
22. Layer P, Go VL, DiMango EP. 1986. Fate of pancreatin enzymes during small intestinal aboral transit in humans. Am J Physiol 251:G475-80.
23. Liu K. 1997. Nonfermented oriental soyfoods. In: Soybeans: chemistry, technology & utilization. New York: Intl. Thomson Publishing, p 137-217.
24. Lo WMY, Li-Chan ECY. 2005. Angiotensin I-converting enzyme inhibitory peptides from in vitro pepsin-pancreatin digestion of soy protein. J Agric Food Chem 53:3369-76.
25. Mainville I, Arcand Y, Farnworth ER. 2005. A dynamic model that simulates the human upper gastrointestinal tract for the study of probiotics. Int J Food Microbiol 99:287-96.
26. Mark KS, Davis TP. 2000. Stroke: development, prevention and treatment with peptidase inhibitors. Peptides 21:1965-73.
27. Masuda O, Nakamura Y, Takano T. 1996. Antihypertensive peptides are present in aorta after oral administration of sour milk containing these peptides to spontaneously hypertensive rats. J Nutr 126:3063-8.
28. Meisel H. 1997. Biochemical properties of regulatory peptides derived from milk proteins. Biopolymers 43:119-28.
29. Minekus M, Marteau P, Havenaar R, Huis in't Veld JHJ. 1995. A multicompartmental dynamic computer-controlled model simulating the stomach and the small intestine. Alt Lab Anim 23:197-209.
30. Nelson DL, Cox MM. 2000. Amino acids, peptides, and proteins. In: Lehninger principles of biochemistry. 3rd ed. New York: Worth Publishers, p 115-58.
31. Pripp AH, Isaksson T, Stepaniak L. 2004. Quantitative structure-activity relationship modeling of ACE-inhibitory peptides derived from milk proteins. Eur Food Res Technol 219:579-83.
32. Seppo L, Jauhiaianen T, Poussa T, Korpela R. 2003. A fermented milk high in bioactive peptides has a blood-pressure-lowering effect in hypertensive subjects. Am J Clin Nutr 77:326-30.
33. Shin ZI, Yu R, Park SA, Ghung DK, An CW, Nam HS, Kim KS, Lee HJ. 2001. His-His-Leu, an angiotensin I converting enzyme inhibitory peptide derived from Korean soybean paste, exerts antihypertensive activity in vivo. J Agric Food Chem 49:3004-9.
34. Sica DA. 2003. Angiotensin-converting enzyme inhibitors. In: Izzo JL, Black HR, Goodfriend TL, Sowers JR, Weder AB, Appel LJ, Sheps SG, Sica DA, Vidt DG, editors. Hypertension primer. 3rd ed. Baltimore, Md.: Lippincott Williams & Wilkins. p 426-9.
35. Skidgel RA, Erdös EG. 2003. Angiotensin I-converting enzyme and neprilysin (neutral endopeptidase). In: Izzo JL, Black HR, Goodfriend TL, Sowers JR, Weder AB, Appel LJ, Sheps SG, Sica DA, Vidt DG, editors. Hypertension primer. 3rd ed. Baltimore, Md.: Lippincott Williams & Wilkins. p 17-9.
36. Sturrock ED, Natesh R, van Rooyen JM, Archarya KR. 2004. Structure of angiotensin I-converting enzyme. Cell Molec Life Sci 61:2677-86.
37. Wu J, Ding X. 2002. Characterization of inhibition and stability of soy-protein-derived angiotensin I-converting enzyme inhibitory peptides. Food Res Int 35:367-75.