Islet transplantation, stem cell transfer and regenerative therapy in diabetes mellitus;Inselzelltransplantation, stammzelltherapie und regenerative therapie bei diabetes mellitus

Deutsche Medizinische Wochenschrift

Volumn 131, Issue 16, 2006, Pages 903-906

  Bretzel, Reinhard G ^a   Eckhard, M ^a   Jahr, H ^a   Brendel, M D ^a  

^a UNIVERSITY HOSPITAL GIESSEN   (Germany)

Author keywords

Diabetes mellitus; Islet transplantation; Stem cell transfer

Indexed keywords

CYTOKINE; EPIDERMAL GROWTH FACTOR; EXENDIN 4; TRANSCRIPTION FACTOR PAX4; TUMOR NECROSIS FACTOR ALPHA;

CELL TRANSFER; CELL TRANSPLANTATION; DIABETES MELLITUS; GENE THERAPY; HUMAN; PANCREAS ISLET CELL; REGENERATION; REVIEW; STEM CELL;

ANIMALS; CELL DIFFERENTIATION; DIABETES MELLITUS, TYPE 1; FOLLOW-UP STUDIES; GENE THERAPY; GRAFT SURVIVAL; HUMANS; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; REGENERATION; STEM CELL TRANSPLANTATION; STEM CELLS;

EID: 33646258969     PISSN: 00120472     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-939867     Document Type: Review

References (17)

1. Assady S, Moor G, Amit M, Hskovitz-Eldor J, Skorecki KL, Tzuckerman M. Insulin production by human embryonic stem cells. Diabetes 2001; 50: 1691-1697
2. Biason-Lauber A, Boehm B, Lang-Muritano M, Ganthier BR, Brun T, Wollheim CB, Schoenle EJ. Association of childhood type 1 diabetes mellitus with a variant of PAX4: possible link to beta cell regenerative capacity. Diabetologia 2005; 48: 900-905
3. Bonner-Weir S, Taneja M, Weir GC, Tatarkiewicz K, Song KH, Sharma A, O'Neil JJ. In vitro cultivation of human islets from expanded ductal tissue. Proc Natl Acad Sci USA 2000; 97: 7999-8004
4. Brendel MD, Eckhard M, Brandhorst D, Brandhorst H, Winter D, Jaeger C, Jahr H, Ziegler A, Iken M, Shen H, Weimer R, Rau W, Padberg W, Bretzel RG. Inselzelltransplantation - aktueller Stand und Perspektiven. Diab Stoffw 2003; 12: 239-251
5. Bretzel RG, Brandhorst D, Brandhorst H, Eckhard M, Ernst W, Friemann S, Rau W, Weimar B, Rauber K, Hering BJ, Brendel MD. Improved survival of intra-portal pancreatic islet cell allografts in patients with type-1 diabetes mellitus by refined peritransplant management. J Mol Med 1999; 77: 140-143
6. Bretzel RG, Browatzki CC, Schultz A, Brandhorst H, Klitscher D, Bollen CC, Raptis G, Friemann S, Ernst W, Rau WS, Hering BJ. Clinical islet transplantation in diabetes mellitus - report of the International Islet Transplant Registry and the Giessen Center experience. Diab Stoffw 1993; 2: 378-390
7. Bretzel RG, Richardt M, Menden A, Federlin K. Pankreas-B-Zellregeneration nach Inseltransplantation beim experimentellen Diabetes mellitus. Verh Dtsch Ges Inn Med 1984; 90: 1471-1477
8. Dor V, Brown J, Martinez OJ, Melton DA. Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation. Nature 2004; 429: 41-46
9. Jahr H, Wagner S, Brendel M, Bretzel RG. Gastrin-induced insulin production in hepatocyte G2 cells. Diabetologia 2005(suppl 148: A153
10. Ju Q, Edelstein D, Brendel MD, Brandhorst D, Brandhorst H, Bretzel RG, Brownlee M. Transduction of non-dividing adult human pancreatic beta-cells by an integrating lentiviral vector. Diabetologia 1998; 41: 736-739
11. Kodama S, Kuhtreiber W, Fujimura S, Dale EA, Faustman DL. Islet regeneration during the reversal of autoimmune diabetes in NOD mice. Science 2003; 302: 1223-1227
12. Narushima M, Kobayashi NM, Okitsu T, Tanaka Y, Li S-A, Chen Y, Miki A, Tanaka K, Nakaji S, Takei K, Gutierrez AS, Rivas-Carrillo JD, Navarro-Alvarez N, Jun H-S, Westerman KA, Noguchi H, Lakey JRT, Leboulch P, Tanaka N, Yoon J-W. A human β-cell line for transplantation therapy to control type 1 diabetes. Nat Biotech 2005; 23: 1274-1282
13. Raeder H, Johansson S, Holm PI, Haldorsen IS, Mas E, Sbarra V, Nermoen I, Eide SA, Grevle L, Bjorkhaug L, Sagen JV, Aksnes L, Sovik O, Lombardo D, Molven A, Njolstad PR. Mutations in the CEL VNTR cause a syndrome of diabetes and pancreatic exocrine dysfunction. Nat Genet 2006; 38: 54-62
14. Ruhnke M, Ungefroren H, Nussler A, Martin F, Brulport M, Schormann W, Hengstler JG, Klapper W, Ulrichs K, Hutchinson JA, Soria B, Parwaresch RM, Heeckt P, Kremer B, Fändrich F. Differentiation of in vitro - modified human peripheral blood monocytes into hepatocyte-like and pancreatic islet-like cells. Gastroenterology 2005; 128: 1774-1786
15. Ryan EA, Paty BW, Senior PA, Bigam D, Alfadhli E, Kneteman NM, Lakey JR, Shapiro AM. Five-year follow-up after clinical islet transplantation. Diabetes 2005; 54: 2060-2069
16. Shapiro AJM, Lakey JRT, Ryan EA, Korbutt GS, Toth E, Warnock GL, Kneteman NM, Rajotte RV. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 2000; 323: 230-238
17. Zhang Y-Q, Kritzik M, Sarvetnick N. Identification and expansion of pancreatic stem/progenitor cells. J Cell Mol Med 2005; 9: 331-344