-
1
-
-
0030725756
-
Furin: A mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins
-
Nakayama, K. (1997) Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins. Biochem. J. 327, 625-635
-
(1997)
Biochem. J.
, vol.327
, pp. 625-635
-
-
Nakayama, K.1
-
2
-
-
0036791359
-
Furin at the cutting edge: From protein traffic to embryogenesis and disease
-
Thomas, G. (2002) Furin at the cutting edge: from protein traffic to embryogenesis and disease. Nat. Rev. Mol. Cell Biol. 3, 753-766
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 753-766
-
-
Thomas, G.1
-
3
-
-
0036882391
-
Precursor processing by kex2/furin proteases
-
Rockwell, N. C., Krysan, D. J., Komiyama, T. and Fuller, R. S. (2002) Precursor processing by kex2/furin proteases. Chem. Rev. 102, 4525-4548
-
(2002)
Chem. Rev.
, vol.102
, pp. 4525-4548
-
-
Rockwell, N.C.1
Krysan, D.J.2
Komiyama, T.3
Fuller, R.S.4
-
4
-
-
0031995477
-
The proprotein convertases
-
Steiner, D. F. (1998) The proprotein convertases. Curr. Opin. Chem. Biol. 2, 31-39
-
(1998)
Curr. Opin. Chem. Biol.
, vol.2
, pp. 31-39
-
-
Steiner, D.F.1
-
5
-
-
0038461962
-
Curbing activation: Proprotein convertases in homeostasis and pathology
-
Taylor, N. A., Van De Ven, W. J. and Creemers, J. W. (2003) Curbing activation: proprotein convertases in homeostasis and pathology. FASEB J. 17, 1215-1227
-
(2003)
FASEB J.
, vol.17
, pp. 1215-1227
-
-
Taylor, N.A.1
Van De Ven, W.J.2
Creemers, J.W.3
-
6
-
-
0037066315
-
The ordered and compartment-specific autoproteolytic removal of the furin intramolecular chaperone is required for enzyme activation
-
Anderson, E. D., Molloy, S. S., Jean, F., Fei, H., Shimamura, S. and Thomas, G. (2002) The ordered and compartment-specific autoproteolytic removal of the furin intramolecular chaperone is required for enzyme activation. J. Biol. Chem. 277, 12879-12890
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 12879-12890
-
-
Anderson, E.D.1
Molloy, S.S.2
Jean, F.3
Fei, H.4
Shimamura, S.5
Thomas, G.6
-
7
-
-
0034671486
-
Processing and sorting of the prohormone convertase 2 propeptide
-
Muller, L., Cameron, A., Fortenberry, Y., Apletalina, E. V. and Lindberg, I. (2000) Processing and sorting of the prohormone convertase 2 propeptide. J. Biol. Chem. 275, 39213-39222
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 39213-39222
-
-
Muller, L.1
Cameron, A.2
Fortenberry, Y.3
Apletalina, E.V.4
Lindberg, I.5
-
8
-
-
0037063322
-
Ectodomain shedding of furin: Kinetics and role of the cysteine-rich region
-
Denault, J., Bissonnette, L., Longpre, J., Charest, G., Lavigne, P. and Leduc, R. (2002) Ectodomain shedding of furin: kinetics and role of the cysteine-rich region. FEBS Lett. 527, 309-314
-
(2002)
FEBS Lett.
, vol.527
, pp. 309-314
-
-
Denault, J.1
Bissonnette, L.2
Longpre, J.3
Charest, G.4
Lavigne, P.5
Leduc, R.6
-
9
-
-
26844560128
-
Evidence for proprotein convertase activity in the endoplasmic reticulum/early Golgi
-
Salvas, A., Benjannet, S., Reudelhuber, T. L., Chrétien, M. and Seidah, N. G. (2005) Evidence for proprotein convertase activity in the endoplasmic reticulum/early Golgi. FEBS Lett. 579, 5621-5625
-
(2005)
FEBS Lett.
, vol.579
, pp. 5621-5625
-
-
Salvas, A.1
Benjannet, S.2
Reudelhuber, T.L.3
Chrétien, M.4
Seidah, N.G.5
-
10
-
-
0028237286
-
The neuroendocrine polypeptide 7B2 is an endogenous inhibitor of prohormone convertase PC2
-
U.S.A.
-
Martens, G. J., Braks, J. A., Eib, D. W., Zhou, Y. and Lindberg, I. (1994) The neuroendocrine polypeptide 7B2 is an endogenous inhibitor of prohormone convertase PC2. Proc. Natl. Acad. Sci. U.S.A. 91, 5784-5787
-
(1994)
Proc. Natl. Acad. Sci.
, vol.91
, pp. 5784-5787
-
-
Martens, G.J.1
Braks, J.A.2
Eib, D.W.3
Zhou, Y.4
Lindberg, I.5
-
11
-
-
0034651077
-
Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing
-
Fricker, L. D., McKinzie, A. A., Sun, J., Curran, E., Qian, Y., Yan, L., Patterson, S. D., Courchesne, P. L., Richards, B., Levin, N. et al. (2000) Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing. J. Neurosci. 20, 639-648
-
(2000)
J. Neurosci.
, vol.20
, pp. 639-648
-
-
Fricker, L.D.1
McKinzie, A.A.2
Sun, J.3
Curran, E.4
Qian, Y.5
Yan, L.6
Patterson, S.D.7
Courchesne, P.L.8
Richards, B.9
Levin, N.10
-
12
-
-
0037372081
-
The cystatin-related epididymal spermatogenic protein inhibits the serine protease prohormone convertase 2
-
Cornwall, G. A., Cameron, A., Lindberg, I., Hardy, D. M., Cormier, N. and Hsia, N. (2003) The cystatin-related epididymal spermatogenic protein inhibits the serine protease prohormone convertase 2. Endocrinology 144, 901-908
-
(2003)
Endocrinology
, vol.144
, pp. 901-908
-
-
Cornwall, G.A.1
Cameron, A.2
Lindberg, I.3
Hardy, D.M.4
Cormier, N.5
Hsia, N.6
-
13
-
-
7544234501
-
Inhibition of furin by serpin Spn4A from Drosophila melanogaster
-
Oley, M., Letzel, M. C. and Ragg, H. (2004) Inhibition of furin by serpin Spn4A from Drosophila melanogaster. FEBS Lett. 577, 165-169
-
(2004)
FEBS Lett.
, vol.577
, pp. 165-169
-
-
Oley, M.1
Letzel, M.C.2
Ragg, H.3
-
14
-
-
3042639565
-
Drosophila serpin 4 functions as a neuroserpin-like inhibitor of subtilisin-like proprotein convertases
-
Osterwalder, T., Kuhnen, A., Leiserson, W. M., Kim, Y. S. and Keshishian, H. (2004) Drosophila serpin 4 functions as a neuroserpin-like inhibitor of subtilisin-like proprotein convertases. J. Neurosci. 24, 5482-5491
-
(2004)
J. Neurosci.
, vol.24
, pp. 5482-5491
-
-
Osterwalder, T.1
Kuhnen, A.2
Leiserson, W.M.3
Kim, Y.S.4
Keshishian, H.5
-
15
-
-
3242682247
-
The Spn4 gene of Drosophila encodes a potent furin-directed secretory pathway serpin
-
U.S.A.
-
Richer, M. J., Keays, C. A., Waterhouse, J., Minhas, J., Hashimoto, C. and Jean, F. (2004) The Spn4 gene of Drosophila encodes a potent furin-directed secretory pathway serpin. Proc. Natl. Acad. Sci. U.S.A. 101, 10560-10565
-
(2004)
Proc. Natl. Acad. Sci.
, vol.101
, pp. 10560-10565
-
-
Richer, M.J.1
Keays, C.A.2
Waterhouse, J.3
Minhas, J.4
Hashimoto, C.5
Jean, F.6
-
16
-
-
0035823595
-
The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature
-
Silverman, G. A., Bird, P. I., Carrell, R. W., Church, F. C., Coughlin, P. B., Gettins, P. G., Irving, J. A., Lomas, D. A., Luke, C. J., Moyer, R. W. et al. (2001) The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature. J. Biol. Chem. 276, 33293-33296
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 33293-33296
-
-
Silverman, G.A.1
Bird, P.I.2
Carrell, R.W.3
Church, F.C.4
Coughlin, P.B.5
Gettins, P.G.6
Irving, J.A.7
Lomas, D.A.8
Luke, C.J.9
Moyer, R.W.10
-
17
-
-
0036882395
-
Serpin structure, mechanism, and function
-
Gettins, P. G. W. (2002) Serpin structure, mechanism, and function. Chem. Rev. 102, 4751-4804
-
(2002)
Chem. Rev.
, vol.102
, pp. 4751-4804
-
-
Gettins, P.G.W.1
-
18
-
-
0037178277
-
Widespread occurrence of serpin genes with multiple reactive centre-containing exon cassettes in insects and nematodes
-
Krüger, O., Ladewig, J., Köster, K. and Ragg, H. (2002) Widespread occurrence of serpin genes with multiple reactive centre-containing exon cassettes in insects and nematodes. Gene 293, 97-105
-
(2002)
Gene
, vol.293
, pp. 97-105
-
-
Krüger, O.1
Ladewig, J.2
Köster, K.3
Ragg, H.4
-
19
-
-
0033965609
-
A novel Drosophila serpin that inhibits serine proteases
-
Han, J., Zhang, H., Min, G., Kemler, D. and Hashimoto, C. (2000) A novel Drosophila serpin that inhibits serine proteases. FEBS Lett. 468, 194-198
-
(2000)
FEBS Lett.
, vol.468
, pp. 194-198
-
-
Han, J.1
Zhang, H.2
Min, G.3
Kemler, D.4
Hashimoto, C.5
-
20
-
-
6044221292
-
The chordate amphioxus: An emerging model organism for developmental biology
-
Holland, L. Z., Laudet, V. and Schubert, M. (2004) The chordate amphioxus: an emerging model organism for developmental biology. Cell. Mol. Life Sci. 61, 2290-2308
-
(2004)
Cell. Mol. Life Sci.
, vol.61
, pp. 2290-2308
-
-
Holland, L.Z.1
Laudet, V.2
Schubert, M.3
-
21
-
-
0025634026
-
Evolution of the insulin superfamily: Cloning of a hybrid insulin/insulin-like growth factor cDNA from amphioxus
-
U.S.A.
-
Chan, S. J., Cao, Q. P. and Steiner, D. F. (1990) Evolution of the insulin superfamily: cloning of a hybrid insulin/insulin-like growth factor cDNA from amphioxus. Proc. Natl. Acad. Sci. U.S.A. 87, 9319-9323
-
(1990)
Proc. Natl. Acad. Sci.
, vol.87
, pp. 9319-9323
-
-
Chan, S.J.1
Cao, Q.P.2
Steiner, D.F.3
-
22
-
-
0028910326
-
Proprotein convertases in amphioxus: Predicted structure and expression of proteases SPC2 and SPC3
-
U.S.A.
-
Oliva, Jr, A. A., Steiner, D. F. and Chan, S. J. (1995) Proprotein convertases in amphioxus: predicted structure and expression of proteases SPC2 and SPC3. Proc. Natl. Acad. Sci. U.S.A. 92, 3591-3595
-
(1995)
Proc. Natl. Acad. Sci.
, vol.92
, pp. 3591-3595
-
-
Oliva Jr., A.A.1
Steiner, D.F.2
Chan, S.J.3
-
23
-
-
0342879885
-
Evolution of the prohormone convertases: Identification of a homologue of PC6 in the protochordate amphioxus
-
Oliva, Jr, A. A., Chan, S. J. and Steiner, D. F. (2000) Evolution of the prohormone convertases: identification of a homologue of PC6 in the protochordate amphioxus. Biochim. Biophys. Acta 1477, 338-348
-
(2000)
Biochim. Biophys. Acta
, vol.1477
, pp. 338-348
-
-
Oliva Jr., A.A.1
Chan, S.J.2
Steiner, D.F.3
-
24
-
-
0000385045
-
Molecular characterization, enzymatic analysis, and purification of murine proprotein convertase-1/3 (PC1/PC3) secreted from recombinant baculovirus-infected insect cells
-
Boudreault, A., Gauthier, D., Rondeau, N., Savaria, D., Seidah, N. G., Chrétien, M. and Lazure, C. (1998) Molecular characterization, enzymatic analysis, and purification of murine proprotein convertase-1/3 (PC1/PC3) secreted from recombinant baculovirus-infected insect cells. Protein Expr. Purif. 14, 353-366
-
(1998)
Protein Expr. Purif.
, vol.14
, pp. 353-366
-
-
Boudreault, A.1
Gauthier, D.2
Rondeau, N.3
Savaria, D.4
Seidah, N.G.5
Chrétien, M.6
Lazure, C.7
-
25
-
-
4444240521
-
Improved PC1/3 production through recombinant expression in insect cells and larvae
-
Rabah, N., Gauthier, D. J., Gauthier, D. and Lazure, C. (2004) Improved PC1/3 production through recombinant expression in insect cells and larvae. Protein Expr. Purif. 37, 377-384
-
(2004)
Protein Expr. Purif.
, vol.37
, pp. 377-384
-
-
Rabah, N.1
Gauthier, D.J.2
Gauthier, D.3
Lazure, C.4
-
26
-
-
0042121237
-
Multiple sequence alignment with the Clustal series of programs
-
Chenna, R., Sugawara, H., Koike, T., Lopez, R., Gibson, T. J., Higgins, D. G. and Thompson, J. D. (2003) Multiple sequence alignment with the Clustal series of programs. Nucleic Acids Res. 31, 3497-3500
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 3497-3500
-
-
Chenna, R.1
Sugawara, H.2
Koike, T.3
Lopez, R.4
Gibson, T.J.5
Higgins, D.G.6
Thompson, J.D.7
-
27
-
-
0035060052
-
Vertebrate serpins: Construction of a conflict-free phylogeny by combining exon-intron and diagnostic site analyses
-
Ragg, H., Lokot, T., Kamp, P. B., Atchley, W. R. and Dress, A. (2001) Vertebrate serpins: construction of a conflict-free phylogeny by combining exon-intron and diagnostic site analyses. Mol. Biol. Evol. 18, 577-584
-
(2001)
Mol. Biol. Evol.
, vol.18
, pp. 577-584
-
-
Ragg, H.1
Lokot, T.2
Kamp, P.B.3
Atchley, W.R.4
Dress, A.5
-
28
-
-
0023728105
-
The behavior and significance of slow-binding enzyme-inhibitors
-
Morrison, J. F. and Walsh, C. T. (1988) The behavior and significance of slow-binding enzyme-inhibitors. Adv. Enzymol. Relat. Areas Mol. Biol. 61, 201-301
-
(1988)
Adv. Enzymol. Relat. Areas Mol. Biol.
, vol.61
, pp. 201-301
-
-
Morrison, J.F.1
Walsh, C.T.2
-
29
-
-
0029003409
-
Theoretical and practical aspects of proteinase inhibition kinetics
-
Bieth, J. G. (1995) Theoretical and practical aspects of proteinase inhibition kinetics. Methods Enzymol. 248, 59-84
-
(1995)
Methods Enzymol.
, vol.248
, pp. 59-84
-
-
Bieth, J.G.1
-
30
-
-
0032972509
-
PSORT: A program for detecting sorting signals in proteins and predicting their subcellular localization
-
Nakai, K. and Horton, P. (1999) PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization. Trends Biochem. Sci. 24, 34-35
-
(1999)
Trends Biochem. Sci.
, vol.24
, pp. 34-35
-
-
Nakai, K.1
Horton, P.2
-
31
-
-
0025788321
-
Mechanism of serpin action: Evidence that C1 inhibitor functions as a suicide substrate
-
Patston, P. A., Gettins, P., Beechem, J. and Schapira, M. (1991) Mechanism of serpin action: evidence that C1 inhibitor functions as a suicide substrate. Biochemistry 30, 8876-8882
-
(1991)
Biochemistry
, vol.30
, pp. 8876-8882
-
-
Patston, P.A.1
Gettins, P.2
Beechem, J.3
Schapira, M.4
-
32
-
-
0029874550
-
Interaction of subtilisins with serpins
-
Komiyama, T., Gron, H., Pemberton, P. A. and Salvesen, G. S. (1996) Interaction of subtilisins with serpins. Protein Sci. 5, 874-882
-
(1996)
Protein Sci.
, vol.5
, pp. 874-882
-
-
Komiyama, T.1
Gron, H.2
Pemberton, P.A.3
Salvesen, G.S.4
-
33
-
-
4644356938
-
Identification and activity of a lower eukaryotic serine proteinase inhibitor (serpin) from Cyanea capillata: Analysis of a jellyfish serpin, jellypin
-
Cole, E. B., Miller, D., Rometo, D., Greenberg, R. M., Brömme, D., Cataltepe, S., Pak, S. C., Mills, D. R., Silverman, G. A. and Luke, C. J. (2004) Identification and activity of a lower eukaryotic serine proteinase inhibitor (serpin) from Cyanea capillata: analysis of a jellyfish serpin, jellypin. Biochemistry 43, 11750-11759
-
(2004)
Biochemistry
, vol.43
, pp. 11750-11759
-
-
Cole, E.B.1
Miller, D.2
Rometo, D.3
Greenberg, R.M.4
Brömme, D.5
Cataltepe, S.6
Pak, S.C.7
Mills, D.R.8
Silverman, G.A.9
Luke, C.J.10
-
34
-
-
0031917385
-
Inhibition of soluble recombinant furin by human proteinase inhibitor 8
-
Dahlen, J. R., Jean, F., Thomas, G., Foster, D. C. and Kisiel, W. (1998) Inhibition of soluble recombinant furin by human proteinase inhibitor 8. J. Biol. Chem. 273, 1851-1854
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 1851-1854
-
-
Dahlen, J.R.1
Jean, F.2
Thomas, G.3
Foster, D.C.4
Kisiel, W.5
-
35
-
-
0141509877
-
Conserved Ser residues, the shutter region, and speciation in serpin evolution
-
Krem, M. M. and Di Cera, E. (2003) Conserved Ser residues, the shutter region, and speciation in serpin evolution. J. Biol. Chem. 278, 37810-37814
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 37810-37814
-
-
Krem, M.M.1
Di Cera, E.2
-
36
-
-
0036083664
-
Proprotein convertases in tumor progression and malignancy: Novel targets in cancer therapy
-
Khatib, A. M., Siegfried, G., Chretien, M., Metrakos, P. and Seidah, N. G. (2002) Proprotein convertases in tumor progression and malignancy: novel targets in cancer therapy. Am. J. Pathol. 160, 1921-1935
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 1921-1935
-
-
Khatib, A.M.1
Siegfried, G.2
Chretien, M.3
Metrakos, P.4
Seidah, N.G.5
-
37
-
-
19544393760
-
Cutting back on pro-protein convertases: The latest approaches to pharmacological inhibition
-
Fugère, M. and Day, R. (2005) Cutting back on pro-protein convertases: the latest approaches to pharmacological inhibition. Trends Pharmacol. Sci. 26, 294-301
-
(2005)
Trends Pharmacol. Sci.
, vol.26
, pp. 294-301
-
-
Fugère, M.1
Day, R.2
|