Specific binding of non-steroidal anti-inflammatory drugs (NSAIDs) to phospholipase A2: Structure of the complex formed between phospholipase A2 and diclofenac at 2.7 Å resolution

Acta Crystallographica Section D: Biological Crystallography

Volumn 62, Issue 4, 2006, Pages 410-416

  Singh, Nagendra ^a   Jabeen, Talat ^a   Sharma, Sujata ^a   Somvanshi, R K ^a   Dey, Sharmistha ^a   Srinivasan, A ^a   Singh, T P ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; DICLOFENAC; ENZYME INHIBITOR; GROUP II SECRETORY PHOSPHOLIPASE A2; NONSTEROID ANTIINFLAMMATORY AGENT; PHOSPHOLIPASE A; VIPER VENOM; WATER;

ANIMAL; ARTICLE; BINDING SITE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; CRYSTALLIZATION; DRUG ANTAGONISM; ELECTRICITY; ENZYMOLOGY; KINETICS; METABOLISM; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SNAKE; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BINDING SITES; CALCIUM; CATALYSIS; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DICLOFENAC; ELECTROSTATICS; ENZYME INHIBITORS; KINETICS; MODELS, MOLECULAR; PHOSPHOLIPASES A; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RUSSELL'S VIPER; VIPER VENOMS; WATER;

DABOIA RUSSELLII PULCHELLA; SARCODINA;

EID: 33646240583     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S0907444906003660     Document Type: Article

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