In vitro and in vivo inhibition of skin matrix metalloproteinases by Pothomorphe umbellata root extract

Photochemistry and Photobiology

Volumn 82, Issue 2, 2006, Pages 439-442

  Ropke, Cristina D ^a   Da Silva, Vanessa V ^a   Kera, Clarissa Z ^a   Miranda, Denise V ^a   De Almeida, Rebeca L ^a   Sawada, Tânia C H ^a   Barros, Silvia B M ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

4 NEROLIDYLCATECHOL; 4-NEROLIDYLCATECHOL; CATECHOL DERIVATIVE; ENZYME INHIBITOR; GELATIN; GELATINASE A; GELATINASE B; MATRIX METALLOPROTEINASE; PLANT EXTRACT; RADIOPROTECTIVE AGENT;

ANIMAL; ARTICLE; CHEMISTRY; COMPARATIVE STUDY; DOSE RESPONSE; DRUG ANTAGONISM; ENZYMOLOGY; HAIRLESS MOUSE; ISOLATION AND PURIFICATION; METABOLISM; METHODOLOGY; MOUSE; PATHOLOGY; PHYTOTHERAPY; PIPERACEAE; PLANT ROOT; RADIATION INJURY; SKIN; TIME; ULTRAVIOLET RADIATION;

ANIMALS; CATECHOLS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GELATIN; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MATRIX METALLOPROTEINASES; MICE; MICE, INBRED HRS; PHYTOTHERAPY; PIPERACEAE; PLANT EXTRACTS; PLANT ROOTS; RADIATION INJURIES, EXPERIMENTAL; RADIATION-PROTECTIVE AGENTS; SKIN; TIME FACTORS; ULTRAVIOLET RAYS;

LEPIANTHES PELTATA;

EID: 33646238965     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1562/2005-06-29-RA-596     Document Type: Article

References (22)

1. Matsumura, Y. and H. N. Ananthaswamy (2002) Short-term and long-term cellular and molecular events following UV irradiation of skin: implications for molecular medicine. Expert. Rev. Mol. Med. 2002, 1-22.
2. Podhaisky, H. P., S. Riemschneider and W. Wohlrab (2002) UV light and oxidative damage of the skin. Pharmazie 57, 30-33.
3. Sander, C. S., H. Chang, S. Salzmann, C. S. Muller, S. Ekanayake-Mudiyanselage, P. Elsner and J. J. Thiele (2002) Photoaging is associated with protein oxidation in human skin in vivo. J. Invest. Dermatol. 118, 618-625.
4. Rittie, L. and G. J. Fisher (2002) UV-light-induced signal cascades and skin aging. Ageing Res. Rev. 1, 705-720.
5. Inomata, S., Y. Matsunaga, S. Amano, K. Takada, K. Kobayashi, M. Tsunenaga, T. Nishiyama, Y. Kohno and M. Fukuda (2003) Possible involvement of gelatinases in basement membrane damage and wrinkle formation in chronically ultraviolet B-exposed hairless mouse. J. Invest Dermatol. 120, 128-134.
6. Kerkela, E. and U. Saarialho-Kere (2003) Matrix metalloproteinases in tumor progression: focus on basal and squamous cell skin cancer. Exp. Dermatol. 12, 109-125.
7. Vayalil, P. K., A. Mittal, Y. Hara, C. A. Elmets and S. K. Katiyar (2004) Green tea polyphenols prevent ultraviolet light-induced oxidative damage and matrix metalloproteinases expression in mouse skin. J. Invest Dermatol. 122, 1480-1487.
8. Ropke, C. D., R. R. Meirelles, V. V. da Silva, T. C. H. Sawada and S. B. M. Barros (2003) Pothomorphe umbellata extract prevents alpha-tocopherol depletion after UV-irradiation. Photochem. Photobiol. 78, 436-439.
9. Barros, S. B. M., D. S. Teixeira, A. E. Aznar, J. A. Moreira Jr, I. Ishii and P. C. D. Freitas (1996) Antioxidant activity of ethanolic extracts of Pothomorphe umbellata L. Miq. Ciência e Cultura 48, 114-116.
10. Desmarchelier, C., S. Barros, M. Repetto, L. R. Latorre, M. Kato, J. Coussio and G. Ciccia (1997) 4-Nerolidylcatechol from Pothomorphe spp. scavenges peroxyl radicals and inhibits Fe(II)-dependent DNA damage. Planta Med. 63, 561-563.
11. Ropke, C. D., T. C. H. Sawada, V. V. da Silva, N. S. Michalany and S. B. M. Barros (2005) Photoprotective effect of Pothomorphe umbellata root extract against ultraviolet radiation induced chronic skin damage in the hairless mouse. Clin. Exp. Dermatol. 30, 272-276.
12. Ropke, C. D., T. M. Kaneko, R. M. Rodrigues, V. V. da Silva, S. Barros, T. C. H. Sawada, M. J. Kato and S. B. M. Barros (2002) Evaluation of percutaneous absorption of 4-nerolidylcatechol from four topical formulations. Int. J. Pharm. 249, 109-116.
13. Gustafson, K. R., J. H. Cardelina, J. B. Mc Mahon, K. P. Pannell, G. M. Cragg and M. R. Boyd (1992) The peltatols, novel HIV-inhibitory catechol derivatives from Pothomorphe peltata. J. Org. Chem. 57, 2809-2811.
14. Kijjoa, A., A. M. Giesbrecht, M. K. Akissue, O. R. Gottlieb and H. E. Gottlieb (1980) 4-nerolidylcatechol from Pothomorphe umbellata. Planta Med. 39, 85-87.
15. Egeblad, M. and Z. Werb (2002) New functions for the matrix metalloproteinases in cancer progression. Nat. Rev. Cancer 2, 161-174.
16. Warner, R. L., N. Bhagavathula, K. C. Nerusu, H. Lateef, E. Younkin, K. J. Johnson and J. Varani (2004) Matrix metalloproteinases in acute inflammation: induction of MMP-3 and MMP-9 in fibroblasts and epithelial cells following exposure to pro-inflammatory mediators in vitro. Exp. Mol. Pathol. 76, 189-195.
17. Lowry, O. H., N. J. Rosebrough, A. L. Farr and R. J. Randall (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265-275.
18. Saito, M., K. Saito, N. Kunisaki and S. Kimura (2002) Green tea polyphenols inhibit metalloproteinase activities in the skin, muscle, and blood of rainbow trout. J. Agric. Food. Chem. 50, 7169-7174.
19. Jurkiewicz, B. A. and G. R. Buettner (1994) Ultraviolet light-induced free radical formation in skin: an electron paramagnetic resonance study. Photochem. Photobiol. 59, 1-4.
20. Rosario, H. S., S. W. Waldo, S. A. Becker and G. W. Schmid-Schonbein (2004) Pancreatic trypsin increases matrix metalloproteinase-9 accumulation and activation during acute intestinal ischemia-reperfusion in the rat. Am. J. Pathol. 164, 1707-1716.
21. Schornagel, I. J., V. Sigurdsson, E. H. Nijhuis, C. A. Bruijnzeel-Koomen and E. F. Knol (2004) Decreased neutrophil skin infiltration after UVB exposure in patients with polymorphous light eruption. J. Invest Dermatol. 123, 202-206.
22. Grimm, T., A. Schafer and P. Hogger (2004) Antioxidant activity and inhibition of matrix metalloproteinases by metabolites of maritime pine bark extract (pycnogenol). Free Radic. Biol. Med. 36, 811-822.