High potassium concentrations protect inner and outer hair cells in the newborn rat culture from ischemia-induced damage

Hearing Research

Volumn 215, Issue 1-2, 2006, Pages 31-38

  Mazurek, Birgit ^a   Amarjargal, Nyamaa ^a   Haupt, Heidemarie ^a   Gross, Johann ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Hair cell loss; Ischemia; Newborn rat; Organ of Corti culture; Potassium

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); LINOPIRDINE; POTASSIUM; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL KCNQ14; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL CULTURE; CELL DAMAGE; CELL LOSS; CELL MEMBRANE; CELL PROTECTION; CELL SURVIVAL; COCHLEA; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORTI ORGAN; DEPOLARIZATION; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; HAIR CELL; ISCHEMIA; NEWBORN; NONHUMAN; PERILYMPH; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT;

ANIMALS; ANIMALS, NEWBORN; CALCIUM; CALCIUM-TRANSPORTING ATPASES; HAIR CELLS; INDOLES; ISCHEMIA; KCNQ POTASSIUM CHANNELS; ORGAN CULTURE TECHNIQUES; POTASSIUM; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; PYRIDINES; RATS; RATS, WISTAR; SODIUM-CALCIUM EXCHANGER; THIOUREA;

EID: 33646232225     PISSN: 03785955     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.heares.2006.02.010     Document Type: Article

References (40)

1. Babnigg G., Zagranichnaya T., Wu X., and Villereal M.L. Differential tyrosine phosphorylation of plasma membrane Ca2+-ATPase and regulation of calcium pump activity by carbachol and bradykinin. J. Biol. Chem. 278 (2003) 14872-14882
2. Beisel K.W., Nelson N.C., Delimont D.C., and Fritzsch B. Longitudinal gradients of KCNQ4 expression in spiral ganglion and cochlear hair cells correlate with progressive hearing loss in DFNA2. Brain Res. Mol. Brain Res. 82 (2000) 137-149
3. Boyer C., Lehouelleur J., and Sans A. Potassium depolarization of mammalian vestibular sensory cells increases [Ca2+]i through voltage-sensitive calcium channels. Eur. J. Neurosci. 10 (1998) 971-975
4. Boyer C., Art J.J., Dechesne C.J., Lehouelleur J., Vautrin J., and Sans A. Contribution of the plasmalemma to Ca2+ homeostasis in hair cells. J. Neurosci. 21 (2001) 2640-2650
5. Cheng A.G., Huang T., Stracher A., Kim A., Liu W., Malgrange B., Lefebvre P.P., Schulman A., and Van de Water T.R. Calpain inhibitors protect auditory sensory cells from hypoxia and neurotrophin-withdrawal induced apoptosis. Brain Res. 850 (1999) 234-243
6. Dallos P. Overviwe: cochlear neurophysiology. In: Dallos P., Popper A.N., and Fay R. (Eds). Springer Handbook of Auditory Research: The Cochlea (1996), Springer, Berlin 1-43
7. Dulon D., Zajic G., and Schacht J. Differential motile response of isolated inner and outer hair cells to stimulation by potassium and calcium ions. Hear. Res. 52 (1991) 225-231
8. Engel J., Michna M., Platzer J., and Striessnig J. Calcium channels in mouse hair cells: function, properties and pharmacology. Adv. Otorhinolaryngol. 59 (2002) 35-41
9. Flock A., and Flock B. Micro-lesions in Reissner's membrane evoked by acute hydrops. Audiol. Neurootol. 8 (2003) 59-69
10. 2+ influx but not Trk activation. J. Neurosci. 15 (1995) 643-664
11. Gao J., Gross J., Andreeva N., Glatzel E., Grutzmann H., Heldt J., Husemann B., Jamielson L., and Andersson K. Hypoxia induces differential changes of dopamine metabolism in mature and immature mesencephalic and diencephalic cell cultures. J. Neural Transm. 106 (1999) 111-122
12. Garcia M.L., Usachev Y.M., Thayer S.A., Strehler E.E., and Windebank A.J. Plasma membrane calcium ATPase plays a role in reducing Ca(2+)-mediated cytotoxicity in PC12 cells. J. Neurosci. Res 64 (2001) 661-669
13. 2+ exchange in the isolated cochlear outer hair cells of the guinea-pig studied by fluorescence image microscopy. Pflugers Arch. 420 (1992) 493-499
14. Jentsch T.J. Neuronal KCNQ potassium channels: physiology and role in disease. Nat. Rev. Neurosci. 1 (2000) 21-30
15. Kennedy H.J. Intracellular calcium regulation in inner hair cells from neonatal mice. Cell Calcium 31 (2002) 127-136
16. Kubisch C., Schroeder B.C., Friedrich T., Lutjohann B., El Amraoui A., Marlin S., Petit C., and Jentsch T.J. KCNQ4, a novel potassium channel expressed in sensory outer hair cells, is mutated in dominant deafness. Cell 96 (1999) 437-446
17. Lampe B.J., Gaskill J.L., Keim S.C., and Brown B.S. Linopirdine reduces stimulus intensity threshold for induction of long-term potentiation in the Schaffer collateral/CA1 pathway in rat hippocampal slices. Neurosci. Lett. 222 (1997) 135-137
18. Lipton P. Ischemic cell death in brain neurons. Physiol Rev. 79 (1999) 1431-1568
19. Lowenheim H., Kil J., Gultig K., and Zenner H.P. Determination of hair cell degeneration and hair cell death in neomycin treated cultures of the neonatal rat cochlea. Hear. Res. 128 (1999) 16-26
20. Martinez-Sanchez M., Striggow F., Schroder U.H., Kahlert S., Reymann K.G., and Reiser G. Na(+) and Ca(2+) homeostasis pathways, cell death and protection after oxygen-glucose-deprivation in organotypic hippocampal slice cultures. Neuroscience 128 (2004) 729-740
21. Mazurek B., Winter E., Fuchs J., Haupt H., and Gross J. Susceptibility of the hair cells of the newborn rat cochlea to hypoxia and ischemia. Hear. Res. 182 (2003) 2-8
22. Meier K., Knepel W., and Schofl C. Potassium depolarization elevates cytosolic free calcium concentration in rat anterior pituitary cells through 1,4-dihydropyridine-sensitive, omega-conotoxin-insensitive calcium channels. Endocrinology 122 (1988) 2764-2770
23. Nilles R. Direct evidence of a protective effect of calcium antagonists on the inner ear. Inhibition of a toxic increase in the calcium level in hair cells of the guinea pig. HNO 43 (1995) 716-723
24. Nouvian R., Ruel J., Wang J., Guitton M.J., Pujol R., and Puel J.L. Degeneration of sensory outer hair cells following pharmacological blockade of cochlear KCNQ channels in the adult guinea pig. Eur. J. Neurosci. 17 (2003) 2553-2562
25. Okano Y., and Iwai H. Effect of the high potassium medium on cultured cochlear epithelial cells. Arch. Otorhinolaryngol. 209 (1975) 121-125
26. Oliver D., Knipper M., Derst C., and Fakler B. Resting potential and submembrane calcium concentration of inner hair cells in the isolated mouse cochlea are set by KCNQ-type potassium channels. J. Neurosci. 23 (2003) 2141-2149
27. 2+-ATPase by calmodulin. Biophys. J. 87 (2004) 1892-1899
28. Pottorf W.J., and Thayer S.A. Transient rise in intracellular calcium produces a long-lasting increase in plasma membrane calcium pump activity in rat sensory neurons. J. Neurochem. 83 (2002) 1002-1008
29. Romero P.J., and Romero E. The modulation of the calcium pump of human red cells by Na+ and K+. Biochim. Biophys. Acta 778 (1984) 245-252
30. Seidman M.D., Quirk W.S., and Shirwany N.A. Mechanisms of alterations in the microcirculation of the cochlea. Ann. N.Y. Acad. Sci. 884 (1999) 226-232
31. Semaan M.T., Alagramam K.N., and Megerian C.A. The basic science of Meniere's disease and endolymphatic hydrops. Curr. Opin. Otolaryngol. Head Neck Surg. 13 (2005) 301-307
32. Shieh C.C., Coghlan M., Sullivan J.P., and Gopalakrishnan M. Potassium channels: molecular defects, diseases, and therapeutic opportunities. Pharmacol. Rev. 52 (2000) 557-594
33. i in apical and basal outer hair cells from guinea pigs. Hear. Res. 154 (2001) 81-87
34. Tran Ba Huy P. Endolymphatic deafness: a particular variety of cochlear disorder. ORL J. Otorhinolaryngol. Relat Spec. 64 (2002) 120-124
35. Usachev Y.M., Toutenhoofd S.L., Goellner G.M., Strehler E.E., and Thayer S.A. Differentiation induces up-regulation of plasma membrane Ca(2+)-ATPase and concomitant increase in Ca(2+) efflux in human neuroblastoma cell line IMR-32. J. Neurochem. 76 (2001) 1756-1765
36. Wangemann P. K+ cycling and the endocochlear potential. Hear. Res. 165 (2002) 1-9
37. Xiao A.Y., Homma M., Wang X.Q., Wang X., and Yu S.P. Role of K(+) efflux in apoptosis induced by AMPA and kinate in mouse cortical neurons. Neuroscience 108 (2001) 61-67
38. 2+ stores in the survival of developing cultured neurons. J. Neurochem. 73 (1999) 457-465
39. Zenner H.P. K+-induced motility and depolarization of cochlear hair cells. Direct evidence for a new pathophysiological mechanism in Meniere's disease. Arch. Otorhinolaryngol. 243 (1986) 108-111
40. Zenner H.P., Reuter G., Zimmermann U., Gitter A.H., Fermin C., and LePage E.L. Transitory endolymph leakage induced hearing loss and tinnitus: depolarization, biphasic shortening and loss of electromotility of outer hair cells. Eur. Arch. Otorhinolaryngol. 251 (1994) 143-153