Characterization of astaxanthin esters in Haematococcus pluvialis by liquid chromatography-atmospheric pressure chemical ionization mass spectrometry

Analytical Biochemistry

Volumn 352, Issue 2, 2006, Pages 176-181

  Miao, Fengping ^a,b   Lu, Dayan ^a   Li, Yeguang ^a   Zeng, Mingtao ^c  

^a Wuhan Institute of Botany Chinese Academy of Sciences   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

Astacin esters; Astaxanthin esters; Haematococcus pluvialis; HPLC; LC (APCI)MS

Indexed keywords

ATMOSPHERIC CHEMISTRY; ATMOSPHERIC IONIZATION; ATMOSPHERIC PRESSURE; ESTERS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION SOURCES; IONIZATION OF LIQUIDS; LIQUIDS; MASS SPECTROMETRY; NEGATIVE IONS; POSITIVE IONS;

ASTAXANTHIN; ATMOSPHERIC PRESSURE CHEMICAL IONIZATION MASS SPECTROMETRY; GAMMA LINOLENIC ACIDS; HAEMATOCOCCUS PLUVIALIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY-DIODE ARRAY DETECTORS; HPLC; LC-(APCI)MS; MAXIMUM ABSORBANCE;

FATTY ACIDS;

ASTACIN; ASTAXANTHIN; CAROTENOID; ESTER DERIVATIVE; FATTY ACID; GAMMA LINOLENIC ACID; LINOLEIC ACID; WATER;

ARTICLE; ATMOSPHERIC PRESSURE; CHEMICAL ANALYSIS; DIODE; GREEN ALGA; HAEMATOCOCCUS PLUVIALIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMER; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL;

CHLOROPHYTA; HAEMATOCOCCUS PLUVIALIS;

EID: 33646155318     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2006.03.006     Document Type: Article

References (23)

1. Johnson E.A., and Gil-Hwan A. Astaxanthin from microbial sources. Crit. Rev. Biotechnol. 11 (1991) 297-326
2. Miki W. Biological functions and activities of animal carotenoids. Pure Appl. Chem. 63 (1991) 141-146
3. Mortensen A., Skibsted L.H., Sampson J., Rice-Evans C., and Everett S.A. Comparative mechanisms and rates of free radical scavenging by carotenoid antioxidants. FEBS Lett. 418 (1997) 91-97
4. Mascio D., Kaiser S.P., and Sies H. Lycopene as the most efficient biological carotenoid singlet oxygen quencher. Arch. Biochem. Biophys. 274 (1989) 532-538
5. Shinidzu N., Goto M., and Miki W. Carotenoids as singlet oxygen quenchers in marine organisms. Fish. Sci. 61 (1996) 134-137
6. Naguib Y. Antioxidant activities of astaxanthin and related carotenoids. J. Agric. Chem. 48 (2000) 1150-1154
7. Lim G.B., Lee S.Y., Lee E.K., Haam S.J., and Kim W.S. Separation of astaxanthin from red yeast Phaffia rhodozyma by supercritical carbon dioxide extraction. Biochem. Eng. J. 11 (2002) 181-187
8. Todd Lorenz R., and Cysewski G.R. Commercial potential for Haematococcus microalgae as a natural source of astaxanthin. Trends Biotechnol. 18 (2000) 160-167
9. Yuan J.P., Gong X.D., and Chen F. Separation and identification of astaxanthin esters and chlorophylls in Haematococcus lacustris by HPLC. Biotechnol. Techniques 10 (1996) 655-660
10. Breithaupt D.E. Identification and quantification of astaxanthin esters in shrimp (Pandalus borealis) and in a microalga (Haematococcus pluvialis) by liquid chromatography-mass spectrometry using negative ion atmospheric pressure chemical ionization. J. Agric. Food Chem. 52 (2004) 3870-3875
11. Yuan J.P., and Chen F. Chromatographic separation and purification of trans-astaxanthin from the extracts of Haematococcus pluvialis. J. Agric. Food Chem. 46 (1998) 3371-3375
12. Renstrom B., and Liaaen-Jensen S. Fatty acid composition of some esterified carotenols. Comp. Biochem. Physiol. B 69 (1981) 625-627
13. Kobayashi M., Kakizono T., and Nagai S. Astaxanthin production by a green alga, Haematococcus pluvialis, accompanied with morphological changes in acetate media. J. Ferment. Bioeng. 71 (1991) 335-339
14. Grung M., D'Souza F.M.L., Borowitzka M., and Liaaen-Jensen S. Algal carotenoids: 51. Secondary carotenoids: 2. Haematococcus pluvialis aplanospores as a source of (3S,3′S)-astaxanthin esters. J. Appl. Phycol. 4 (1992) 165-171
15. Vecchi M., Muduna V., and Glinz E. HPLC separation and determination of astacene, semiastacene, and other keto-carotenoids. J. High Resolut. Chromatogr. Chromatogr. Commun. 10 (1987) 348-351
16. Hagen C., Braune W., Birckner E., and Nuske J. Functional aspects of secondary carotenoids in Haematococcus lacustris (Girod) Rostafinski (Volvocales). New Phytol. 125 (1993) 625-633
17. Fan L., Vonshak A., Gabbay R., Hirshberg J., Cohen Z., and Boussiba S. The biosynthetic pathway of astaxanthin in a green alga Haematococcus pluvialis as indicated by inhibition with diphenylamine. Plant Cell Physiol. 36 (1995) 1519-1524
18. Yuan J.P., Gong X.D., and Chen F. Separation and analysis of carotenoids and chlorophylls in Haematococcus lacustris by high-performance liquid chromatography photodiode array detection. J. Agric. Food Chem. 45 (1997) 1952-1956
19. White D.A., Page G.I., Waile J.S., Moody A.J., and Davies S.J. Effect of esterification on the absorption of astaxanthin in rainbow trout, Oncorhynchus mykiss (Walbaum). Aquaculture Res. 33 (2002) 343-350
20. Richard B., Breemen V., Huang C.R., Tan Y.C., Sander L.C., and Schilling A.B. Liquid chromatography/mass spectrometry of carotenoids using atmospheric pressure chemical ionization. J. Mass Spectrom. 31 (1996) 975-981
21. Weller P., and Breithaupt D.E. Identification and quantification of zeaxanthin esters in plants using liquid chromatography-mass spectrometry. J. Agric. Food Chem. 51 (2003) 7044-7049
22. Takaichi S., Matsui K., Nakamura M., Muramatsu M., and Hanada S. Fatty acids of astaxanthin esters in krill determined by mild mass spectrometry. Comp. Biochem. Physiol. B 136 (2003) 317-322
23. Denery J.R., Dragull K., Tang C.S., and Li Q.X. Pressurized fluid extraction of carotenoids from Haematococcus pluvialis and Dunaliella salina and kavalactone from Piper methysticum. Anal. Chim. Acta 501 (2004) 175-181