Xenopus laevis is a potential alternative model animal species to study reproductive toxicity of phytoestrogens

Aquatic Toxicology

Volumn 77, Issue 3, 2006, Pages 250-256

  Cong, Lin ^a,b   Qin, Zhan Fen ^a   Jing, Xiang Ning ^b   Yang, Lei ^a,b   Zhou, Jing Ming ^a   Xu, Xiao Bai ^a  

^a RESEARCH CENTER FOR ECO ENVIRONMENTAL SCIENCES   (China)

^b BEIJING FORESTRY UNIVERSITY   (China)

Author keywords

Feminization; Phytoestrogen; Quercetin; Reproductive toxicity; Xenopus laevis

Indexed keywords

ESTRADIOL; PHYTOESTROGEN; QUERCETIN;

ANIMAL COMMUNITY; FEMINIZATION; FROG; HISTOLOGY; HORMONE; METAMORPHOSIS; TOXICITY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; DEVELOPMENTAL STAGE; ENVIRONMENTAL EXPOSURE; EXPERIMENTAL MODEL; FEMALE; FEMINIZATION; FROG; GONAD; GONAD DEVELOPMENT; HERMAPHRODITISM; HISTOLOGY; LONG TERM EXPOSURE; MALE; METAMORPHOSIS; MORPHOLOGY; NONHUMAN; OOCYTE; OOCYTE DEVELOPMENT; OVARY; PHENOTYPE; PRIORITY JOURNAL; REPRODUCTIVE TOXICITY; SEMINIFEROUS TUBULE; SPERMATOCYTE; SPERMATOGENESIS; SPERMATOGONIUM; TESTIS; TESTIS DEVELOPMENT; TESTIS DISEASE; TISSUE STRUCTURE; XENOPUS LAEVIS;

ANIMALS; ESTRADIOL; FEMALE; GONADS; LARVA; MALE; MODELS, ANIMAL; PHYTOESTROGENS; QUERCETIN; REPRODUCTION; SEX RATIO; SURVIVAL RATE; XENOPUS LAEVIS;

ANIMALIA; ANURA; XENOPUS LAEVIS;

EID: 33646086969     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aquatox.2005.12.014     Document Type: Article

References (49)

1. Adams N.R. Organizational and activational effects of phytoestrogens on the reproductive tract of the ewe. Proc. Soc. Exp. Biol. Med. 208 (1995) 87-91
2. Adlercreutz H. Phyto-oestrogens and cancer. Lancet Oncol. 3 (2002) 364-373
3. Awoniyi C.A., Roberts D., Veeramachaneni D.N., Hurst B.S., Tucker K.E., and Schlaff W.D. Reproductive sequelae in female rats after in utero and neonatal exposure to the phytoestrogen genistein. Fertil. Steril. 70 (1998) 440-447
4. Bennetts H.W., Underwood E.T., and Shier F.C. A specific breeding problem of sheep on subterranean clover pastures in Western Australia. Aust. Vet. J. 22 (1946) 2-12
5. Campbell D.R., and Kurzer M.S. Flavonoid inhibition of aromatase enzyme activity in human preadipocytes. J. Steroid. Biochem. Mol. Biol. 46 (1993) 381-388
6. Carr J.A., Gentles A., Smith E.E., Goleman W.L., Urquidi L.J., Thuett K., Kendall R.J., Giesy J.P., Gross T.S., Solomon K.R., and Van Der Kraak G. Response of larval Xenopus laevis to atrazine: assessment of growth, metamorphosis, and gonadal and laryngeal morphology. Environ. Toxicol. Chem. 22 (2003) 396-405
7. Chang C.Y., and Witschi E. Genetic control and hormonal reversal of sex differentiation in Xenopus. Proc. Soc. Exp. Biol. Med. 93 (1956) 140-144
8. Everitt J.I., and Foster P.M.D. Laboratory animal science issues in the design and conduct of studies with endocrine-active compounds. ILAR J. 45 (2004) 417-424
9. Gallien L. Inversion totale du sexe chez Xenopus laevis Daudin à la suite d' un traitement gynog è ne par le benzoate d' oestradiol administr é pendant la vie larvaire. C. R. S é ances Acad. Sci. (Pris) 273 (1953) 1565-1566
10. Gallien L. In: Loft B. (Ed). Intersexuality. Physiology of the Amphibia vol. II (1974), Academic Press, New York and London 523-527
11. Hayes T.B., Collins A., Lee M., Mendoza M., Noriega N., Stuart A.A., and Vonk A. Hermaphroditic, demasculinize frogs after exposure to the herbicide atrazine at low ecologically relevant doses. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 5476-5480
12. Hayes T.B. Sex determination and primary sex differentiation in amphibians: genetic and developmental mechanism. J. Exp. Zool. 281 (1998) 373-399
13. Klann A., Levy G., Lutz I., Müller C., Kloas W., and Hildebrandt J.P. Estrogen-like effects of ultraviolet screen 3-(4-methylbenzylidene)-camphor (Eusolex 6300) on cell proliferation and gene induction in mammalian and amphibian cells. Environ. Res. 97 (2005) 274-281
14. Kloas W. Amphibians as a model for the study of endocrine disruptors. Int. Rev. Cytol. 216 (2002) 1-57
15. Kloas W., Lutz I., and Einspanier R. Amphibians as a model to study endocrine disruptors. II. Estrogenic activity of environmental chemicals in vitro and in vivo. Sci. Total. Environ. 225 (1999) 59-68
16. Lamartiniere C.A., Moore J., Holland M., and Barnes S. Neonatal genistein chemoprevents mammary cancer. Proc. Soc. Exp. Biol. Med 208 (1995) 120-123
17. Lamartiniere C.A., Wang J., Smith-Johnson M., and Eltoum I.E. Daidzein: bioavailability, potential for reproductive toxicity, and breast cancer chemoprevention in female rats. Toxicol. Sci. 65 (2002) 228-238
18. Levy G., Lutz I., Kruger A., and Kloas W. Bisphenol A induces feminization in Xenopus laevis tadpoles. Environ. Res. 94 (2004) 102-111
19. MacLatchy D.L., and Van Der Kraak G.J. The phytoestrogen beta-sitosterol alters the reproductive endocrine status of goldfish. Toxicol. Appl. Pharmacol. 134 (1995) 305-312
20. Mitchell J.H., Cawood E., Kinniburgh D., Provan A., Collins A.R., and Irvine D.S. Effect of a phytoestrogen food supplement on reproductive health in normal males. Clin. Sci. (Lond). 100 (2001) 613-618
21. Miyata S., Koike S., and Kubo T. Hormonal reversal and the genetic control of sex differentiation in Xenopus. Zool. Sci. 16 (1999) 335-340
22. Miyata S., and Kubo T. In vitro effects of estradiol and aromatase inhibitor treatment on sex differentiation in Xenopus laevis gonads. Gen. Comp. Endocrinol. 119 (2000) 105-110
23. Naciff J.M., Overmann G.J., Torontali S.M., Carr G.J., Tiesman J.P., and Daston G.P. Impact of the phytoestrogen content of laboratory animal feed on the gene expression profile of the reproductive system in the immature female rat. Environ. Health Perspect. 112 (2004) 1519-1526
24. National Research Council. NIH Guide for the Care and Use of Laboratory Animals (1996), National Academy Press, Washington, DC
25. Nieuwkoop P.D., and Faber J. Normal Table of Xenopus laevis (Daudin) (1956), Amsterdam, North-Holland
26. Odum J., Tinwell H., Jones K., Van Miller J.P., Joiner R.L., Tobin G., Kawasaki H., Deghenghi R., and Ashby J. Effect of rodent diets on the sexual development of the rat. Toxicol. Sci. 61 (2001) 115-127
27. Opalka M., Kaminska B., Ciereszko R., and Dusza L. Genistein affects testosterone secretion by Leydig cells in roosters (Gallus gallus domesticus). Reprod. Biol. 4 (2004) 185-193
28. Papiez M., Gancarczyk M., and Bilinska B. The compounds from the hollyhock extract (Althaea rosea Cav. var. nigra) affect the aromatization in rat testicular cells in vivo and in vitro. Folia. Histochem. Cytobiol. 40 (2002) 353-359
29. Pickford D.B., Hetheridge M.J., Caunter J.E., Hall A.T., and Hutchinson T.H. Assessing chronic toxicity of bisphenol A to larvae of the African clawed frog (Xenopus laevis) in a flow-through exposure system. Chemosphere 53 (2003) 223-235
30. Pickford D.B., and Morris I.D. Inhibition of gonadotropin-induced oviposition and ovarian steroidogenesis in the African clawed frog (Xenopus laevis) by the pesticide methoxychlor. Aquat. Toxicol. 62 (2003) 179-194
31. Qin Z.F., Zhou J.M., Chu S.G., and Xu X.B. Effects of Chinese domestic polychlorinated biphenyls (PCBs) on gonadal differentiation in Xenopus laevis. Environ. Health Perspect. 111 (2003) 553-556
32. Roberts D., Veeramachaneni D.N., Schlaff W.D., and Awoniyi C.A. Effects of chronic dietary exposure to genistein, a phytoestrogen, during various stages of development on reproductive hormones and spermatogenesis in rats. Endocrine 13 (2000) 281-286
33. Sanderson J.T., Hordijk J., Denison M.S., Springsteel M.F., Nantz M.H., and van den Berg M. Induction and inhibition of aromatase (CYP19) activity by natural and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells. Toxicol. Sci. 82 (2004) 70-79
34. Schmitt E., and Stopper H. Estrogenic activity of naturally occurring anthocyanidins. Nutr. Cancer 41 (2001) 145-149
35. Setchell K.D. Phytoestrogens: the biochemistry, physiology, and implications for human health of soy isoflavones. Am. J. Clin. Nutr. 68 Suppl. 6 (1998) 1333s-1346s
36. Stokes W.S. Selecting appropriate animal models and experimental designs for endocrine disruptor research and testing studies. ILAR J. 45 (2004) 387-393
37. Strauss L., Makela S., Joshi S., Huhtaniemi I., and Santti R. Genistein exerts estrogen-like effects in male mouse reproductive tract. Mol. Cell. Endocrinol. 144 (1998) 83-93
38. Stroheker T., Cabaton N., Berges R., Lamothe V., Lhuguenot J.C., and Chagnon M.C. Influence of dietary soy isoflavones on the accessory sex organs of the Wistar rat. Food Chem. Toxicol. 41 (2003) 1175-1183
39. Thigpen J.E., Setchell K.D., Saunders H.E., Haseman J.K., Grant M.G., and Forsythe D.B. Selecting the appropriate rodent diet for endocrine disruptor research and testing studies. ILAR J. 45 (2004) 401-416
40. Tou J.C.L., Chen J., and Thompson L.U. Dose, timing, and duration of flaxseed exposure affect reproductive indices and sex hormone levels in rats. J. Toxicol. Environ. Health A 56 (1999) 555-570
41. U.S. EPA, 1998. Endocrine Disruptor Screening and Testing Advisory Committee (EDSTAC): Final Report. U.S. Environmental Protection Agency, Washington, DC.
42. van der Schalie W.H., Gardner Jr. H.S., Bantle J.A., De Rosa C.T., Finch R.A., Reif J.S., Reuter R.H., Backer L.C., Burger J., Folmar L.C., and Stokes W.S. Animals as sentinels of human health hazards of environmental chemicals. Environ. Health Perspect. 107 (1999) 309-315
43. van Wyk J.H., Pool E.J., and Leslie A.J. The effects of anti-androgenic and estrogenic disrupting contaminants on breeding gland (nuptial pad) morphology, plasma testosterone levels, and plasma vitellogenin levels in male Xenopus laevis (African clawed frog). Arch. Environ. Contam. Toxicol. 44 (2003) 247-256
44. Villalpando I., and Merchant-Larios H. Determination of the sensitive stages for gonadal sex-reversal in Xenopus laevis tadpoles. Int. J. Dev. Biol. 34 (1990) 281-285
45. Wanichacheewa S., Singtripop T., Sassa S., Sakamoto S., and Mori T. Decrease in the number of sperm associated with decreased blood testosterone levels in male rats treated with extracts from seven plants consumed by natives of northern Thailand. Environ. Toxicol. Pharmacol. 10 (2001) 1-4
46. Weber K.S., Setchell K.D., Stocco D.M., and Lephart E.D. Dietary soy-phytoestrogens decrease testosterone levels and prostate weight without altering LH, prostate 5alpha-reductase or testicular steroidogenic acute regulatory peptide levels in adult male Sprague-Dawley rats. J. Endocrinol. 170 (2001) 591-599
47. Wisniewski A.B., Klein S.L., Lakshmanan Y., and Gearhart J.P. Exposure to genistein during gestation and lactation demasculinizes the reproductive system in rats. J. Urol. 169 (2003) 1582-1586
48. Witschi E., and Allison J. Responses of Xenopus and Alytes to the administration of some steroid hormones. Anat. Rec. 108 (1950) 589-590
49. Zhang L., Khan I.A., and Foran C.M. Characterization of the estrogenic response to genistein in Japanese medaka (Oryzias latipes). Comp. Biochem. Physiol. C. Toxicol. Pharmacol. 132 (2002) 203-211