A novel kind of nitrogen heterocycle compound induces apoptosis of human chronic myelogenous leukemia K562 cells

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 11, 2006, Pages 3766-3774

  Ding, Guoyu ^a,b   Liu, Feng ^a   Yang, Ting ^b   Jiang, Yuyang ^a,b   Fu, Hua ^b   Zhao, Yufen ^b  

^a Guangdong Province   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

Author keywords

Caspase 3,8,9; G1 arrest; K562 cell apoptosis; Nitrogen heterocycle compounds

Indexed keywords

ACRIDINE ORANGE; CASPASE 3; CASPASE 8; CASPASE 9; DEATH RECEPTOR; DNA FRAGMENT; LIPOCORTIN 5; NITROGEN; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL STRAIN K 562; CHEMOPROPHYLAXIS; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; ENZYME ASSAY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; PROTEIN TARGETING;

APOPTOSIS; CASPASES; CELL CYCLE; CELL PROLIFERATION; DNA FRAGMENTATION; DRUG EVALUATION, PRECLINICAL; G1 PHASE; HETEROCYCLIC COMPOUNDS; HUMANS; K562 CELLS; LEUKEMIA, MYELOID, CHRONIC; MITOCHONDRIA; MOLECULAR STRUCTURE; NITROGEN; REACTIVE OXYGEN SPECIES; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS;

EID: 33646061008     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.01.050     Document Type: Article

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