IL-17F sequence variant (His161Arg) is associated with protection against asthma and antagonizes wild-type IL-17F activity

Journal of Allergy and Clinical Immunology

Volumn 117, Issue 4, 2006, Pages 795-801

  Kawaguchi, Mio ^a   Takahashi, Daisuke ^b   Hizawa, Nobuyuki ^b   Suzuki, Shintaro ^a   Matsukura, Satoshi ^a   Kokubu, Fumio ^a   Maeda, Yukiko ^b   Fukui, Yoshinobu ^b   Konno, Satoshi ^b   Huang, Shau Ku ^c   Nishimura, Masaharu ^b   Adachi, Mitsuru ^a  

^a SHOWA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Asthma; candidate gene; case control association analysis; IL 17F; single nucleotide polymorphism

Indexed keywords

ARGININE; CYTOKINE; HISTIDINE; INTERLEUKIN 17; INTERLEUKIN 17 F; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ALLERGIC ASTHMA; AMINO ACID SUBSTITUTION; ARTICLE; ATOPY; BRONCHUS MUCOSA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA POLYMORPHISM; FEMALE; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC CODE; GENETIC RISK; GENETIC VARIABILITY; HOMOZYGOSITY; HUMAN; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; MANTEL HAENSZEL TEST; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; SAMPLE; SINGLE NUCLEOTIDE POLYMORPHISM; WILD TYPE;

ADOLESCENT; ADULT; AGED; AMINO ACID SUBSTITUTION; ASTHMA; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; HAPLOTYPES; HOMOZYGOTE; HUMANS; INTERLEUKIN-17; JAPAN; MALE; MAP KINASE SIGNALING SYSTEM; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RECOMBINANT PROTEINS; VARIATION (GENETICS);

EID: 33646060990     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2005.12.1346     Document Type: Article

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