Stereoselective synthesis of the 5′-hydroxy-5′-phosphonate derivatives of cytidine and cytosine arabinoside

Journal of Organic Chemistry

Volumn 67, Issue 26, 2002, Pages 9331-9339

  Chen, Xuemei ^a   Wiemer, Andrew J ^b   Hohl, Raymond J ^b   Wiemer, David F ^a  

^a E11 SSH   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDES; CATALYST SELECTIVITY; DERIVATIVES; ENZYMES; HYDROLYSIS; SUBSTRATES; SYNTHESIS (CHEMICAL);

STEREOCHIMISTRY;

PHOSPHATE COATINGS;

ALDEHYDE; CYTARABINE DERIVATIVE; CYTIDINE DERIVATIVE; ESTER DERIVATIVE; FUNCTIONAL GROUP; LEWIS ACID; MANDELIC ACID DERIVATIVE; NUCLEOSIDE MONOPHOSPHATE KINASE; PHOSPHITE; PHOSPHONIC ACID DERIVATIVE; TITANIUM TETRACHLORIDE;

ADDITION REACTION; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; DRUG SYNTHESIS; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; HYDROLYSIS; ISOMER; STEREOCHEMISTRY; STEREOISOMERISM;

CYTARABINE; CYTIDINE; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; HYDROLYSIS; K562 CELLS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PHOSPHONIC ACIDS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0037184769     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo020483k     Document Type: Article

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