Stereocontrolled synthesis of hydroxymethylene phosphonate analogues of phosphorylated tyrosine and their conversion to monofluoromethylene phosphonate analogues

Tetrahedron

Volumn 52, Issue 36, 1996, Pages 11725-11738

  Yokomatsu, Tsutomu ^a   Yamagishi, Takehiro ^a   Matsumoto, Keita ^b   Shibuya, Shiroshi ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^b TAISHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PHENYLALANINE DERIVATIVE; PHOSPHONOAMINO ACID; TYROSINE DERIVATIVE;

ARTICLE; CHIRALITY; DRUG SYNTHESIS; PRIORITY JOURNAL; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0030565461     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4020(96)00671-0     Document Type: Article

References (34)

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28. 19
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33. 3) δ 7.38 (2H, d, J=8.2 Hz), 7.16 (2H, d, J=8.2 Hz), 5.80 (1H, s), 4.45 (1H, dq, J-6.7, 6.7 Hz), 4.28-4.12 (1H, m), 2.33 (3H, s), 1.98 (1H, ddd, J=6.2, 12.4, 12.4 Hz), 1.48 (3H, d, J=6.9 Hz), 1.46-1.40 (1H, m), 1.28 (3H, d, J=6.2 Hz).
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