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Volumn 117, Issue 4, 2006, Pages 909-915

Association of CD4 + T-lymphocyte counts and new thymic emigrants in HIV-infected children during successful highly active antiretroviral therapy

Author keywords

CD4 + T lymphocytes; children; HAART; HIV 1 intracellular DNA; immune reconstitution; T cell receptor excision circles

Indexed keywords

EFAVIRENZ; NELFINAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; T LYMPHOCYTE RECEPTOR; VIRUS DNA; VIRUS RNA;

EID: 33646045847     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2006.01.013     Document Type: Article
Times cited : (16)

References (29)
  • 1
    • 0035936007 scopus 로고    scopus 로고
    • Effect of combination therapy including protease inhibitors on mortality among children and adolescents infected with HIV-1
    • Gortmaker S.L., Hughes M., Cervia J., Brady M., Johnson G.M., Seage III G.R., et al. Effect of combination therapy including protease inhibitors on mortality among children and adolescents infected with HIV-1. N Engl J Med 345 (2001) 1522-1528
    • (2001) N Engl J Med , vol.345 , pp. 1522-1528
    • Gortmaker, S.L.1    Hughes, M.2    Cervia, J.3    Brady, M.4    Johnson, G.M.5    Seage III, G.R.6
  • 2
    • 2642709177 scopus 로고    scopus 로고
    • Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators
    • Palella Jr. F.J., Delaney K.M., Moorman A.C., Loveless M.O., Fuhrer J., Satten G.A., et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med 338 (1998) 853-860
    • (1998) N Engl J Med , vol.338 , pp. 853-860
    • Palella Jr., F.J.1    Delaney, K.M.2    Moorman, A.C.3    Loveless, M.O.4    Fuhrer, J.5    Satten, G.A.6
  • 3
    • 0036183627 scopus 로고    scopus 로고
    • Immune reconstitution in patients with HIV infection
    • Sempowski G.D., and Haynes B.F. Immune reconstitution in patients with HIV infection. Annu Rev Med 53 (2002) 269-284
    • (2002) Annu Rev Med , vol.53 , pp. 269-284
    • Sempowski, G.D.1    Haynes, B.F.2
  • 4
    • 0034117263 scopus 로고    scopus 로고
    • CD4+ and CD8+ T lymphocyte regeneration after anti-retroviral therapy in HIV-1-infected children and adult patients
    • Franco J.M., Leon-Leal J.A., Leal M., Cano-Rodriguez A., Pineda J.A., Macias J., et al. CD4+ and CD8+ T lymphocyte regeneration after anti-retroviral therapy in HIV-1-infected children and adult patients. Clin Exp Immunol 119 (2000) 493-498
    • (2000) Clin Exp Immunol , vol.119 , pp. 493-498
    • Franco, J.M.1    Leon-Leal, J.A.2    Leal, M.3    Cano-Rodriguez, A.4    Pineda, J.A.5    Macias, J.6
  • 5
    • 0034656389 scopus 로고    scopus 로고
    • Immune repopulation after HAART in previously untreated HIV-1-infected children. Paediatric European Network for Treatment of AIDS (PENTA) Steering Committee
    • Gibb D.M., Newberry A., Klein N., de Rossi A., Grosch-Woerner I., and Babiker A. Immune repopulation after HAART in previously untreated HIV-1-infected children. Paediatric European Network for Treatment of AIDS (PENTA) Steering Committee. Lancet 355 (2000) 1331-1332
    • (2000) Lancet , vol.355 , pp. 1331-1332
    • Gibb, D.M.1    Newberry, A.2    Klein, N.3    de Rossi, A.4    Grosch-Woerner, I.5    Babiker, A.6
  • 6
    • 0032529682 scopus 로고    scopus 로고
    • Immune reconstitution in HAART-treated children with AIDS. Highly Active Anti-Retroviral Therapy
    • Sharland M., Watkins A.M., Dalgleish A.G., Cammack N., and Westby M. Immune reconstitution in HAART-treated children with AIDS. Highly Active Anti-Retroviral Therapy. Lancet 352 (1998) 577-578
    • (1998) Lancet , vol.352 , pp. 577-578
    • Sharland, M.1    Watkins, A.M.2    Dalgleish, A.G.3    Cammack, N.4    Westby, M.5
  • 7
    • 0030868897 scopus 로고    scopus 로고
    • Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease
    • Autran B., Carcelain G., Li T.S., Blanc C., Mathez D., Tubiana R., et al. Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease. Science 277 (1997) 112-116
    • (1997) Science , vol.277 , pp. 112-116
    • Autran, B.1    Carcelain, G.2    Li, T.S.3    Blanc, C.4    Mathez, D.5    Tubiana, R.6
  • 8
    • 0031882434 scopus 로고    scopus 로고
    • Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: a composite of redistribution and proliferation
    • Pakker N.G., Notermans D.W., de Boer R.J., Roos M.T., de Wolf F., Hill A., et al. Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: a composite of redistribution and proliferation. Nat Med 4 (1998) 208-214
    • (1998) Nat Med , vol.4 , pp. 208-214
    • Pakker, N.G.1    Notermans, D.W.2    de Boer, R.J.3    Roos, M.T.4    de Wolf, F.5    Hill, A.6
  • 9
    • 0037093057 scopus 로고    scopus 로고
    • T-cell repopulation and thymic volume in HIV-1-infected adult patients after highly active antiretroviral therapy
    • Franco J.M., Rubio A., Martinez-Moya M., Leal M., Merchante E., Sanchez-Quijano A., et al. T-cell repopulation and thymic volume in HIV-1-infected adult patients after highly active antiretroviral therapy. Blood 99 (2002) 3702-3706
    • (2002) Blood , vol.99 , pp. 3702-3706
    • Franco, J.M.1    Rubio, A.2    Martinez-Moya, M.3    Leal, M.4    Merchante, E.5    Sanchez-Quijano, A.6
  • 10
    • 0034809303 scopus 로고    scopus 로고
    • Multiple CD4+ cell kinetic patterns and their relationships with baseline factors and virological responses in HIV type 1 patients receiving highly active antiretroviral therapy
    • Wu H., Connick E., Kuritzkes D.R., Landay A., Spritzler J., Zhang B., et al. Multiple CD4+ cell kinetic patterns and their relationships with baseline factors and virological responses in HIV type 1 patients receiving highly active antiretroviral therapy. AIDS Res Hum Retroviruses 17 (2001) 1231-1240
    • (2001) AIDS Res Hum Retroviruses , vol.17 , pp. 1231-1240
    • Wu, H.1    Connick, E.2    Kuritzkes, D.R.3    Landay, A.4    Spritzler, J.5    Zhang, B.6
  • 11
    • 0031885673 scopus 로고    scopus 로고
    • Thymic function can be accurately monitored by the level of recent T cell emigrants in the circulation
    • Kong F., Chen C.H., and Cooper M.D. Thymic function can be accurately monitored by the level of recent T cell emigrants in the circulation. Immunity 8 (1998) 97-104
    • (1998) Immunity , vol.8 , pp. 97-104
    • Kong, F.1    Chen, C.H.2    Cooper, M.D.3
  • 12
    • 0033573914 scopus 로고    scopus 로고
    • T cell receptor gene deletion circles identify recent thymic emigrants in the peripheral T cell pool
    • Kong F.K., Chen C.L., Six A., Hockett R.D., and Cooper M.D. T cell receptor gene deletion circles identify recent thymic emigrants in the peripheral T cell pool. Proc Natl Acad Sci U S A 96 (1999) 1536-1540
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 1536-1540
    • Kong, F.K.1    Chen, C.L.2    Six, A.3    Hockett, R.D.4    Cooper, M.D.5
  • 13
    • 17444372347 scopus 로고    scopus 로고
    • Changes in thymic function with age and during the treatment of HIV infection
    • Douek D.C., McFarland R.D., Keiser P.H., Gage E.A., Massey J.M., Haynes B.F., et al. Changes in thymic function with age and during the treatment of HIV infection. Nature 396 (1998) 690-695
    • (1998) Nature , vol.396 , pp. 690-695
    • Douek, D.C.1    McFarland, R.D.2    Keiser, P.H.3    Gage, E.A.4    Massey, J.M.5    Haynes, B.F.6
  • 14
    • 0037066355 scopus 로고    scopus 로고
    • Immune reconstitution in HIV-1-infected children on antiretroviral therapy: role of thymic output and viral fitness
    • Ometto L., De Forni D., Patiri F., Trouplin V., Mammano F., Giacomet V., et al. Immune reconstitution in HIV-1-infected children on antiretroviral therapy: role of thymic output and viral fitness. AIDS 16 (2002) 839-849
    • (2002) AIDS , vol.16 , pp. 839-849
    • Ometto, L.1    De Forni, D.2    Patiri, F.3    Trouplin, V.4    Mammano, F.5    Giacomet, V.6
  • 15
    • 0036681757 scopus 로고    scopus 로고
    • Increased thymic output after initiation of antiretroviral therapy in human immunodeficiency virus type 1-infected children in the Paediatric European Network for Treatment of AIDS (PENTA) 5 Trial
    • De Rossi A., Walker A.S., Klein N., De Forni D., King D., and Gibb D.M. Increased thymic output after initiation of antiretroviral therapy in human immunodeficiency virus type 1-infected children in the Paediatric European Network for Treatment of AIDS (PENTA) 5 Trial. J Infect Dis 186 (2002) 312-320
    • (2002) J Infect Dis , vol.186 , pp. 312-320
    • De Rossi, A.1    Walker, A.S.2    Klein, N.3    De Forni, D.4    King, D.5    Gibb, D.M.6
  • 16
    • 0037165875 scopus 로고    scopus 로고
    • Effects of highly active antiretroviral therapy on thymical reconstitution of CD4 T lymphocytes in vertically HIV-infected children
    • Correa R., and Munoz-Fernandez A. Effects of highly active antiretroviral therapy on thymical reconstitution of CD4 T lymphocytes in vertically HIV-infected children. AIDS 16 (2002) 1181-1183
    • (2002) AIDS , vol.16 , pp. 1181-1183
    • Correa, R.1    Munoz-Fernandez, A.2
  • 17
    • 0035873422 scopus 로고    scopus 로고
    • Evaluation of T cell receptor gene rearrangement excision circles after antiretroviral therapy in children infected with human immunodeficiency virus
    • Chavan S., Bennuri B., Kharbanda M., Chandrasekaran A., Bakshi S., and Pahwa S. Evaluation of T cell receptor gene rearrangement excision circles after antiretroviral therapy in children infected with human immunodeficiency virus. J Infect Dis 183 (2001) 1445-1454
    • (2001) J Infect Dis , vol.183 , pp. 1445-1454
    • Chavan, S.1    Bennuri, B.2    Kharbanda, M.3    Chandrasekaran, A.4    Bakshi, S.5    Pahwa, S.6
  • 18
    • 0037094107 scopus 로고    scopus 로고
    • Persistence of human immunodeficiency virus (HIV) type 1 DNA in peripheral blood despite prolonged suppression of plasma HIV-1 RNA in children
    • Saitoh A., Hsia K., Fenton T., Powell C.A., Christopherson C., Fletcher C.V., et al. Persistence of human immunodeficiency virus (HIV) type 1 DNA in peripheral blood despite prolonged suppression of plasma HIV-1 RNA in children. J Infect Dis 185 (2002) 1409-1416
    • (2002) J Infect Dis , vol.185 , pp. 1409-1416
    • Saitoh, A.1    Hsia, K.2    Fenton, T.3    Powell, C.A.4    Christopherson, C.5    Fletcher, C.V.6
  • 19
    • 0033576814 scopus 로고    scopus 로고
    • Combination therapy with efavirenz, nelfinavir, and nucleoside reverse-transcriptase inhibitors in children infected with human immunodeficiency virus type 1. Pediatric AIDS Clinical Trials Group 382 Team
    • Starr S.E., Fletcher C.V., Spector S.A., Yong F.H., Fenton T., Brundage R.C., et al. Combination therapy with efavirenz, nelfinavir, and nucleoside reverse-transcriptase inhibitors in children infected with human immunodeficiency virus type 1. Pediatric AIDS Clinical Trials Group 382 Team. N Engl J Med 341 (1999) 1874-1881
    • (1999) N Engl J Med , vol.341 , pp. 1874-1881
    • Starr, S.E.1    Fletcher, C.V.2    Spector, S.A.3    Yong, F.H.4    Fenton, T.5    Brundage, R.C.6
  • 20
    • 0033980093 scopus 로고    scopus 로고
    • PCR-Based assay to quantify human immunodeficiency virus type 1 DNA in peripheral blood mononuclear cells
    • Christopherson C., Kidane Y., Conway B., Krowka J., Sheppard H., and Kwok S. PCR-Based assay to quantify human immunodeficiency virus type 1 DNA in peripheral blood mononuclear cells. J Clin Microbiol 38 (2000) 630-634
    • (2000) J Clin Microbiol , vol.38 , pp. 630-634
    • Christopherson, C.1    Kidane, Y.2    Conway, B.3    Krowka, J.4    Sheppard, H.5    Kwok, S.6
  • 21
    • 18344373740 scopus 로고    scopus 로고
    • Relationship between changes in thymic emigrants and cell-associated HIV-1 DNA in HIV-1-infected children initiating antiretroviral therapy
    • De Rossi A., Walker A.S., De Forni D., Klein N., and Gibb D.M. Relationship between changes in thymic emigrants and cell-associated HIV-1 DNA in HIV-1-infected children initiating antiretroviral therapy. Antivir Ther 10 (2005) 63-71
    • (2005) Antivir Ther , vol.10 , pp. 63-71
    • De Rossi, A.1    Walker, A.S.2    De Forni, D.3    Klein, N.4    Gibb, D.M.5
  • 22
    • 0038363474 scopus 로고    scopus 로고
    • T-cell receptor excisional circles, telomere length, proliferation and apoptosis in peripheral blood mononuclear cells of human immunodeficiency virus-infected individuals after 18 months of treatment induced viral suppression
    • Aladdin H., Katzenstein T., Dreves A.M., Ryder L., Gerstoft J., Skinhoj P., et al. T-cell receptor excisional circles, telomere length, proliferation and apoptosis in peripheral blood mononuclear cells of human immunodeficiency virus-infected individuals after 18 months of treatment induced viral suppression. Scand J Immunol 57 (2003) 485-492
    • (2003) Scand J Immunol , vol.57 , pp. 485-492
    • Aladdin, H.1    Katzenstein, T.2    Dreves, A.M.3    Ryder, L.4    Gerstoft, J.5    Skinhoj, P.6
  • 23
    • 0035964724 scopus 로고    scopus 로고
    • T cell receptor excision circle (TREC) content following maximum HIV suppression is equivalent in HIV-infected and HIV-uninfected individuals
    • Steffens C.M., Smith K.Y., Landay A., Shott S., Truckenbrod A., Russert M., et al. T cell receptor excision circle (TREC) content following maximum HIV suppression is equivalent in HIV-infected and HIV-uninfected individuals. AIDS 15 (2001) 1757-1764
    • (2001) AIDS , vol.15 , pp. 1757-1764
    • Steffens, C.M.1    Smith, K.Y.2    Landay, A.3    Shott, S.4    Truckenbrod, A.5    Russert, M.6
  • 24
    • 0036681857 scopus 로고    scopus 로고
    • Evidence of thymic function in heavily antiretroviral-treated human immunodeficiency virus type 1-infected adults with long-term virologic treatment failure
    • Delgado J., Leal M., Ruiz-Mateos E., Martinez-Moya M., Rubio A., Merchante E., et al. Evidence of thymic function in heavily antiretroviral-treated human immunodeficiency virus type 1-infected adults with long-term virologic treatment failure. J Infect Dis 186 (2002) 410-414
    • (2002) J Infect Dis , vol.186 , pp. 410-414
    • Delgado, J.1    Leal, M.2    Ruiz-Mateos, E.3    Martinez-Moya, M.4    Rubio, A.5    Merchante, E.6
  • 25
    • 0033831175 scopus 로고    scopus 로고
    • Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infection
    • Hazenberg M.D., Otto S.A., Cohen Stuart J.W., Verschuren M.C., Borleffs J.C., Boucher C.A., et al. Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infection. Nat Med 6 (2000) 1036-1042
    • (2000) Nat Med , vol.6 , pp. 1036-1042
    • Hazenberg, M.D.1    Otto, S.A.2    Cohen Stuart, J.W.3    Verschuren, M.C.4    Borleffs, J.C.5    Boucher, C.A.6
  • 26
    • 0036521465 scopus 로고    scopus 로고
    • The role of growth hormone in T-cell development and reconstitution
    • Welniak L.A., Sun R., and Murphy W.J. The role of growth hormone in T-cell development and reconstitution. J Leukoc Biol 71 (2002) 381-387
    • (2002) J Leukoc Biol , vol.71 , pp. 381-387
    • Welniak, L.A.1    Sun, R.2    Murphy, W.J.3
  • 27
    • 0037089233 scopus 로고    scopus 로고
    • Effects of exogenous interleukin-7 on human thymus function
    • Okamoto Y., Douek D.C., McFarland R.D., and Koup R.A. Effects of exogenous interleukin-7 on human thymus function. Blood 99 (2002) 2851-2858
    • (2002) Blood , vol.99 , pp. 2851-2858
    • Okamoto, Y.1    Douek, D.C.2    McFarland, R.D.3    Koup, R.A.4
  • 28
    • 0038216950 scopus 로고    scopus 로고
    • Endogenous IL-7 is associated with increased thymic volume in adult HIV-infected patients under highly active antiretroviral therapy
    • Ruiz-Mateos E., de la Rosa R., Franco J.M., Martinez-Moya M., Rubio A., Soriano N., et al. Endogenous IL-7 is associated with increased thymic volume in adult HIV-infected patients under highly active antiretroviral therapy. AIDS 17 (2003) 947-954
    • (2003) AIDS , vol.17 , pp. 947-954
    • Ruiz-Mateos, E.1    de la Rosa, R.2    Franco, J.M.3    Martinez-Moya, M.4    Rubio, A.5    Soriano, N.6
  • 29
    • 0041330412 scopus 로고    scopus 로고
    • Increased interleukin-7 plasma levels are associated with recovery of CD4+ T cells in HIV-infected children
    • Correa R., Resino S., and Munoz-Fernandez M.A. Increased interleukin-7 plasma levels are associated with recovery of CD4+ T cells in HIV-infected children. J Clin Immunol 23 (2003) 401-406
    • (2003) J Clin Immunol , vol.23 , pp. 401-406
    • Correa, R.1    Resino, S.2    Munoz-Fernandez, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.