Pretransplantation bone disease in patients with primary pulmonary hypertension

Chest

Volumn 129, Issue 4, 2006, Pages 1002-1008

  Tschopp, Oliver ^a   Schmid, Christoph ^a   Speich, Rudolf ^a   Seifert, Burkhardt ^a   Russi, Erich W ^a   Boehler, Annette ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Bone mineral density; Lung transplantation; Osteoporosis; Primary pulmonary hypertension

Indexed keywords

ADULT; ARTICLE; BODY MASS; BONE DENSITY; BONE DISEASE; BONE MASS; CLINICAL ARTICLE; CLINICAL FEATURE; CORRELATION ANALYSIS; DISEASE ACTIVITY; DISEASE COURSE; EARLY DIAGNOSIS; FEMALE; FEMUR NECK; HUMAN; LUMBAR SPINE; LUNG TRANSPLANTATION; MALE; OSTEOPOROSIS; PARAMETER; POPULATION; PREVALENCE; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RETROSPECTIVE STUDY; RISK FACTOR; SEX DIFFERENCE; STATISTICAL SIGNIFICANCE; SWITZERLAND; WALKING;

EID: 33646016592     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.129.4.1002     Document Type: Article

References (36)

1. Aris RM, Neuringer IP, Weiner MA, et al. Severe osteoporosis before and after lung transplantation. Chest 1996; 109:1176-1183
2. Rodino MA, Shane E. Osteoporosis after lung transplantation. Am J Med 1998; 104:459-469
3. Shane E, Papadopoulos A, Staron RB, et al. Bone loss and fracture after lung transplantation. Transplantation 1999; 68:220-227
4. Shane E, Silverberg SJ, Donovan D, et al. Osteoporosis in lung transplantation candidates with end-stage pulmonary disease. Am J Med 1996; 101:262-269
5. Aringer M, Kiener HP, Koeller MD, et al. High turnover bone disease following lung transplantation. Bone 1998; 23:485-488
6. Maalouf NM, Shane E. Osteoporosis after solid organ transplantation. J Clin Endocrinol Metab 2005; 90:2456-2465
7. Ferrari SL, Nicod LP, Hamacher J, et al. Osteoporosis in patients undergoing lung transplantation. Eur Respir J 1996; 9:2378-2382
8. Spira A, Gutierrez C, Chaparro C, et al. Osteoporosis and lung transplantation: a prospective study. Chest 2000; 117:476-481
9. Aris RM, Renner JB, Winders AD, et al. Increased rate of fractures and severe kyphosis: sequelae of living into adulthood with cystic fibrosis. Ann Intern Med 1998; 128:186-193
10. Tschopp O, Boehler A, Speich R, et al. Osteoporosis before lung transplantation; association with low body mass index, but not with underlying disease. Am J Transplantation 2002; 2:167-172
11. Barst RJ, Rubin LJ, Long WA, et al. A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. N Engl J Med 1996; 334:296-301
12. Channick RN, Simonneau G, Sitbon O, et al. Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study. Lancet 2001; 358:1119-1123
13. Rubin LJ, Badesch DB, Barst RJ, et al. Bosentan therapy for pulmonary arterial hypertension. N Engl J Med 2002; 346:896-903
14. Charman SC, Sharples LD, McNeil KD, et al. Assessment of survival benefit after lung transplantation by diagnosis. J Heart Lung Transplant 2002; 2:226-232
15. Speich R, Bochler A, Zollinger A, et al. Die isolierte Lungen-transplantation-Evaluation und erste Resultate. Schweiz Med Wochenschr 1995; 125:786-795
16. Kanis JA, Melton LJ, Christiansen C, et al. The diagnosis of osteoporosis. J Bone Miner Res 1994; 9:1137-1141
17. Felson DT, Zhang Y, Hannan MT, et al. Effects of weight and body mass on bone mineral density in men and women: the Framingham study. J Bone Miner Res 1993; 8:567-573
18. Margolis KL, Ensrud KE, Schreiner PJ, et al. Body size and risk of clinical fracture in older women: study of Osteoporotic Fracture Research Group. Ann Intern Med 2000; 133:123-127
19. Snell GI, Bennetts K, Bartolo J, et al. Body mass index as a predictor of survival in adults with cystic fibrosis referred for lung transplantation. J Heart Lung Transplant 1998; 17:1097-1103
20. Bianda T, Linka A, Junga G, et al. Prevention of osteoporosis in heart transplant recipients: a comparison of calcitonin and pamidronate. Calcif Tissue Int 2000; 67:116-121
21. The International PPH Consortium, Lane KB, Machado RD, et al. Heterozygous germline mutations in BMPR2, encoding a TGF-β receptor, cause familial primary pulmonary hypertension. Nat Genet 2000; 26:81-84
22. Deng Z, Morse JH, Slager SL, et al. Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene. Am J Hum Genet 2000; 67:737-744
23. Thomson JR, Machado RD, Pauciulo MW, et al. Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-β family. J Med Genet 2000; 37:741-745
24. Machado RD, Pauciulo MW, Thompson JR, et al. BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension. Am J Hum Genet 2001; 68:92-102
25. Elliott CG. Genetics of pulmonary arterial hypertension: current and future implications. Semin Respir Crit Care Med 2005; 26:365-371
26. Beppu H, Ichinose F, Kawai N, et al. BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary remodelling response to prolonged hypoxia. Am J Lung Cell Mol Physiol 2004; 287:1241-1247
27. Eddahibi S, Humbert M, Fadel E, et al. Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension. J Clin Invest 2001; 108:1109-1111
28. Launay J-M, Hervé P, Peoc'h K, et al. Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension. Nat Med 2002; 8:1129-1135
29. Tuder RM, Zaiman AL. Prostacyclin analogs as the brakes for pulmonary smooth muscle cell proliferation: is it sufficient to treat severe pulmonary hypertension? Am J Respir Cell Mol Biol 2002; 26:171-174
30. Du L, Sullivan CC, Chu D, et al. Signaling molecules in nonfamilial pulmonary hypertension. N Engl J Med 2003; 348:500-509
31. Miyamoto S, Nagaya N, Satoh T, et al. Clinical correlates and prognostic significance of six-minute walk test in patients with primary pulmonary hypertension. Am J Respir Crit Care Med 2000; 161:487-492
32. Krall EA, Dawson-Hughes B. Walking is related to bone density and rates of bone loss. Am J Med 1994; 96:20-26
33. Gregg EW, Cauley JA, Seeley DG, et al. Physical activity and osteoporotic facture risk in older women. Ann Intern Med 1998; 129:81-88
34. Meyer FJ, Ewert R, Hoeper MM, et al. Peripheral airway obstruction in primary pulmonary hypertension. Thorax 2002; 57:473-476
35. Frost HM. Perspective. On our age-related bone loss: insights from a new paradigm. J Bone Miner Res 1997; 12:1539-1546
36. Cohen A, Sambrook P, Shane E. Management of bone loss after organ transplantation. J Bone Miner Res 2004; 19:1919-1932