Differentiation and function of osteoclasts cultured on bone and cartilage

Journal of Electron Microscopy

Volumn 54, Issue 6, 2005, Pages 529-540

  Suzumoto, Reina ^a   Takami, Masamichi ^a   Sasaki, Takahisa ^a  

^a SHOWA UNIVERSITY   (Japan)

Author keywords

Cartilage resorption; Differentiation; Osteoclast; TRAP; Yeast particles

Indexed keywords

ANIMAL; ARTICLE; BONE; BONE MINERALIZATION; CARTILAGE; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; OSTEOBLAST; PHYSIOLOGY; RABBIT; SCANNING ELECTRON MICROSCOPY;

ANIMALS; BONE AND BONES; CALCIFICATION, PHYSIOLOGIC; CARTILAGE; CELL DIFFERENTIATION; CELLS, CULTURED; MICROSCOPY, ELECTRON, SCANNING; OSTEOBLASTS; RABBITS;

ORYCTOLAGUS CUNICULUS;

BONE; CARTILAGE; CELL MEMBRANES; CYTOLOGY; PHOSPHATASES;

ACID PHOSPHATASE ACTIVITIES; BONE AND CARTILAGES; BONE MARROW; CARTILAGE RESORPTION; DIFFERENTIATION; OSTEOCLAST; OSTEOCLAST DIFFERENTIATION; RESORPTION LACUNAE; TARTRATE-RESISTANT ACID PHOSPHATASE; YEAST PARTICLE;

YEAST;

EID: 33645981292     PISSN: 00220744     EISSN: 14779986     Source Type: Journal    
DOI: 10.1093/jmicro/dfi074     Document Type: Article

References (37)

1. Katagiri T and Takahashi N (2002) Regulatory mechanisms of osteoblast and osteoclast differentiation. Oral Diseases 8: 147-159.
2. Sells Galvin R J, Gatlin C L, Horn J W, and Fuson T R (1999) TGF-β enhances osteoclast differentiation in hematopoietic cell cultures stimulated with RANKL and M-CSF. Biochem. Biophys. Res. Commun. 265: 233-239.
3. Kaneda T, Nojima T, Nakagawa M, Ogasawara A, Kaneko H, Sato T, Mano H, Kumegawa M, and Hakeda Y (2000) Endogenous production of TGF-β is essential for osteoclastogenesis induced by a combination of receptor activator of NF-κB ligand and macrophage-colony-stimulating factor. J. Immunol. 165: 4254-4263.
4. Quinn J M, Itoh K, Udagawa N, Hausler K, Yasuda H, Shima N, Mizuno A, Higashio K, Takahashi N, Suda T, Martin T J, and Gillespie M T (2001) Transforming growth factor β affects osteoclast differentiation via direct and indirect actions. J. Bone Miner. Res. 16: 1787-1794.
5. Itonaga I, Saborkbar A, Sun S G, Kudo O, Danks L, Ferguson D, Fujikawa Y, and Athanasou N A (2004) Transforming growth factor-β induces osteoclast formation in the absence of RANKL. Bone 34: 57-64.
6. +-ATPase and lysosomal cysteine proteinase, cathepsin K, in osteoclasts. Anat. Rec. 270A: 152-161.
7. Sasaki T (2003) Differentiation, functions of osteoclasts and odontoclasts in mineralized tissue resorption. Microsc. Res. Techn. 61: 483-495.
8. Delaisse J M, Andersen T L, Engsig M T, Henriksen K, Troen T, and Blavier L (2003) Matrix metalloproteinases (MMP) and cathepsin K contribute differently to osteoclastic activities. Microsc. Res. Techn. 61: 504-513.
9. Goto T, Yamaza T, and Tanaka T (2003) Cathepsins in the osteoclast. J. Electron Microsc. 52: 551-558.
10. Sasaki T, Kim T, Debari K, and Nagamine H (1996) Cartilage-bone replacement in endochondral ossification of mandibular condylar heads in young beagle dogs. J. Electron Microsc. 45: 213-222.
11. Kugler J H, Tomlinson A, Wagstaff A, and Ward S M (1979) The role of cartilage canals in the formation of secondary centres of ossification. J. Anat. 129: 493-506.
12. Silvestrini G, Ricordi M E, and Bonucci E (1979) Resorption of uncalcified cartilage in the diaphysis of the chick embryo tibia. Cell Tissue Res. 196: 221-235.
13. Sorrell J M and Weiss L (1980) A light and electron microscopic study of the region of cartilage resorption in the embryonic chick femur. Anat. Rec. 198: 513-530.
14. Cole A A and Wezeman F H (1985) Perivascular cells in cartilage canals of the developing mouse epiphysis. Am. J. Anat. 174: 119-129.
15. Lewinson D and Silbermann M (1992) Chondroclasts and endothelial cells collaborate in the process of cartilage resorption. Anat. Rec. 233: 504-514.
16. Lewinson D and Kogan Y (1995) Ontogenesis of chondro/osteoclasts and their precursors in the mandibular condyle of the mouse. Bone 17: 293-299.
17. Nordahl J, Anderson G, and Reinholt FP (1998) Chondroclasts and osteoclasts in bones of young rats: comparison of ultrastructural and functional features. Calcif. Tissue Int. 63: 401-408.
18. 3 have ruffled borders and resorb dentine. Anat. Rec. 224: 279-291.
19. Murakami H, Takahashi N, Sasaki T, Udagawa N, Tanaka S, Nakamura I, Zhang D, Barbier A, and Suda T (1995) A possible mechanism of the specific action of bisphosphonates on osteoclasts: tiludronate preferentially affects polarized osteoclasts having ruffled borders. Bone 17: 137-144.
20. Nakamura I, Gailit J, and Sasaki T (1996) Osteoclast integrin is present in the clear zone and contributes to cellular polarization. Cell Tissue Res. 286: 507-515.
21. Lee R, Lamplugh L, Shepard N L, and Mort J S (1995) The septoclast, a cathepsin B-rich cell involved in the resorption of growth plate cartilage. J. Histochem. Cytochem. 43: 525-536.
22. Lee E R, Murphy G, EL-Alfy M, Davoli M A, Lamplugh L, Docherty A J, and Leblond C P (1999) Active gelatinase B in identified by histozymography in the cartilage resorption sites of developing long bones. Dev. Dyn. 215: 190-205.
23. Lee E R, Lamplugh L, Davoli M A, Beauchemin A, Chan K, Mort J S, and Leblond C P (2001) Enzymes active in the areas undergoing cartilage resorption during the development of the secondary ossification center in the tibiae of rats ages 0-21 days. I. Two groups of proteinases cleave the protein of aggrecan. Dev. Dyn. 222: 52-70.
24. Davoli M A, Lamplugh L, Beauchemin A, Chan K, Mordier S, Mort J S, Murphy G, Docherty A J P, Leblond C P, and Lee E R (2001) Enzymes active in the areas undergoing cartilage resorption during the development of the secondary ossification center in the tibiae of rats aged 0-21 days. II. Two proteinases, gelatinase B and collagenase-3, are implicated in the lysis of collagen fibrils. Dev. Dyn. 222: 71-88.
25. Udagawa N, Takahashi N, Akatsu T, Tanaka H, Sasaki T, Nishihara T, Koga T, Martin T J, and Suda T (1990) Origin of osteoclasts: mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells. Proc. Natl Acad. Sci. USA 87: 7260-7264.
26. Bonewald L F (1995) Regulation, regulatory activities of transforming growth factor beta. Crit. Rev. Eukaryote Gene Exp. 9: 33-44.
27. Szuwart T, Kierdorf H, Kierdorf U, and Clemen G (2002) Histochemical and ultrastructural studies of cartilage resorption and acid phosphatase activity during antler growth in fallow deer (Dama dama). Anat. Rec. 268: 66-72.
28. Sawae Y, Sahara T, and Sasaki T (2003) Osteoclast differentiation at growth plate cartilage-trabecular bone junction in newborn rat femur. J. Electron Microsc. 52: 493-502.
29. Kawana F and Sasaki T (2003) Osteoclast differentiation and characteristic trabecular bone formation during growth plate destruction in osteoprotegerin-deficient mice. J. Electron Microsc. 52: 515-525.
30. Nair S P, Meghji S, Wilson M, Reddi K, White P, and Henderson B (1996) Bacterially induced bone destruction: Mechanisms and misconception. Infect. Immun. 64: 2371-2380.
31. Akira S, Takeda K, and Kaisho T (2001) Toll-like receptors: critical proteins linking innate and acquired immunity. Nat. Immunol. 2: 675-680.
32. Suda K, Woo J T, Takami M, Sexton P M, and Nagai K (2002) Lipopolysaccharide supports survival and fusion of preosteoclasts independent of TNF-α, IL-1, and RANKL. J. Cell Physiol. 190: 101-108.
33. Itoh K, Udagawa N, Kobayashi K, Suda K, Li X, Takami M, Okahashi N, Nishihara T, and Takahashi N (2003) Lipopolysaccharide promotes the survival of osteoclasts via toll-like receptor 4, but cytokine production of osteoclasts in response to lipopolysaccharide is different from that of macrophages. J. Immunol. 170: 3688-3695.
34. Ozinsky A, Underhill D M, Fontenot J D, Hajjar A M, Smith K D, Wilson C B, Schroeder L, and Aderem A (2000) The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. Proc. Natl Acad. Sci. USA 97: 13766-13771.
35. Hanazawa S, Kawata Y, Murakami Y, Naganuma K, Amano S, Miyata Y, and Kitano S (1995) Porphyomonas gingivalis fimbria-stimulated bone resorption in vitro is inhibited by a tyrosine kinase inhibitor. Infect. Immun. 63: 2374-2377.
36. Yamazaki H and Sasaki T (2005) Effects of osteoprotegerin administration on osteoclast differentiation and trabecular bone structure in osteoprotegerin-deficient mice. J Electron Microsc. 54: 467-477.
37. Vu T H, Shipley J M, Bergers G, Berger J E, Helms J A, Hanahan D, Shapiro S D, Senior R M, and Werb Z (1998) MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes. Cell 93: 411-422.