Design of perfectly symmetric Trp-rich peptides with potent and broad-spectrum antimicrobial activities

International Journal of Antimicrobial Agents

Volumn 27, Issue 4, 2006, Pages 325-330

  Yang, Sung Tae ^a   Shin, Song Yub ^b   Hahm, Kyung Soo ^b   Kim, Jae Il ^a  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

^b Chosun University   (South Korea)

Author keywords

Amphipathic turn structure; Selectivity; Symmetric peptides; Tritrpticin

Indexed keywords

AMPHOLYTE; CATHELICIDIN; INDOLICIDIN; PEPTIDE DI T13; PEPTIDE PSI10; PEPTIDE PST11; PEPTIDE PST11 RK; PEPTIDE PST13 RK; PEPTIDE T13 AM; PEPTIDE T15 AM; PHOSPHATIDYLCHOLINE; POLYPEPTIDE ANTIBIOTIC AGENT; TRITRPTICIN; TRYPTOPHAN DERIVATIVE; UNCLASSIFIED DRUG;

AMIDATION; AMINO ACID SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOTOXICITY; DRUG DESIGN; DRUG PENETRATION; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ERYTHROCYTE; HEMOLYSIS; HUMAN; HUMAN CELL; MEMBRANE PERMEABILITY; MOLECULAR MIMICRY; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIA; BACTERIAL INFECTIONS; CELL MEMBRANE PERMEABILITY; CIRCULAR DICHROISM; DRUG DESIGN; DRUG RESISTANCE, BACTERIAL; ERYTHROCYTES; FLUORESCENT DYES; HEMOLYSIS; LIPOSOMES; MICROBIAL SENSITIVITY TESTS; OLIGOPEPTIDES;

EID: 33645959250     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2005.11.014     Document Type: Article

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