Persisting concentrating and second gas effects on oxygenation during N2O anaesthesia

Anaesthesia

Volumn 61, Issue 4, 2006, Pages 322-329

  Peyton, Phil J ^a   Stuart Andrews, C ^b   Deo, K ^c   Strahan, F ^a   Robinson, G J B ^d   Thompson, B R ^b   Pierce, R ^e  

^a AUSTIN HOSPITAL   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c LA TROBE UNIVERSITY   (Australia)

^d The Alfred ^*  (Australia)

^e UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ISOFLURANE; NITRIC OXIDE; NITROGEN; OXYGEN; INHALATION ANESTHETIC AGENT; NITROUS OXIDE;

ADULT; AGED; ARTERIAL OXYGEN SATURATION; ARTERIAL OXYGEN TENSION; ARTICLE; BLOOD GAS ANALYSIS; BREATHING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; GENERAL ANESTHESIA; HUMAN; INHALATION ANESTHESIA; LUNG GAS EXCHANGE; QUANTITATIVE ANALYSIS; RANDOMIZED CONTROLLED TRIAL; ANALYSIS OF VARIANCE; BLOOD; DRUG EFFECT; HEART MUSCLE REVASCULARIZATION; INTRAOPERATIVE PERIOD; METHODOLOGY; MIDDLE AGED; OXYGEN CONSUMPTION; PRESSURE;

AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; ANESTHESIA, INHALATION; ANESTHETICS, INHALATION; HUMANS; INTERNAL MAMMARY-CORONARY ARTERY ANASTOMOSIS; INTRAOPERATIVE PERIOD; MIDDLE AGED; NITROUS OXIDE; OXYGEN; OXYGEN CONSUMPTION; PARTIAL PRESSURE; PULMONARY GAS EXCHANGE;

EID: 33645899939     PISSN: 00032409     EISSN: 13652044     Source Type: Journal    
DOI: 10.1111/j.1365-2044.2006.04579.x     Document Type: Article

References (25)

1. Eger EI. Effect of inspired anesthetic concentration on the rate of rise of alveolar concentration. Anesthesiology 1962; 24: 153-7.
2. Stoelting RK, Eger EI. An additional explanation for the second gas effect: A concentrating effect. Anesthesiology 1969; 30: 273-7.
3. Sun X, Su F, Shi Y, Lee C. The 'second gas effect' is not a valid concept. Anesthesia and Analgesia 1999; 88: 188-92.
4. 2 O on oxygen uptake. Canadian Journal of Anaesthesia 2000; 47: 506-10.
5. Dueck R, Young I, Clausen J, Wagner P. Altered distribution of pulmonary ventilation and blood flow following induction of inhalational anesthesia. Anesthesiology 1980; 52: 113-25.
6. Peyton P, Robinson G, Thompson B. The effect of ventilation-perfusion inhomogeneity and nitrous oxide on oxygenation in anesthesia: physiological modeling of gas exchange. Journal of Applied Physiology 2001; 91: 17-25.
7. Bindslev L, Hedenstierna G, Santesson J, Gottlieb I, Carvallhas A. Ventilation-perfusion distribution during inhalation anesthesia. Acta Anaesthesiologica Scandinavica 1981; 25: 360-71.
8. Hedenstierna G, Lundh R, Johansson H. Alveolar stability during anesthesia for reconstructive vascular surgery in the leg. Acta Anaesthesiologica Scandinavica 1983; 27: 26-34.
9. Lundh R, Hedenstierna G. Ventilation-perfusion relationships during anesthesia and abdominal surgery. Acta Anaesthesiologica Scandinavica 1983; 27: 167-73.
10. Lundh R, Hedenstierna G. Ventilation-perfusion relationships during halothane anesthesia and mechanical ventilation. effects of varying inspired oxygen concentration. Acta Anaesthesiologica Scandinavica 1984; 28: 191-8.
11. Rehder K, Knopp TJ, Sessler AD, Didier EP. Ventilation-perfusion relationship in young healthy awake and anesthetized-paralyzed man. Journal of Applied Physiology: Respiration Environment Exercise Physiology 1979; 47: 745-53.
12. 2 breathing. Journal of Applied Physiology 1975; 38: 886-95.
13. Joyce CJ, Baker AB, Kennedy RR. Gas uptake from an unventilated area of lung: Computer model of absorption atelectasis. Journal of Applied Physiology 1993; 74: 1107-16.
14. 2 tension difference in anesthetized man. Journal of Applied Physiology 1960; 15: 383-9.
15. 2 analysis in blood and gas. Journal of Applied Physiology: Respiration Environmental and Exercise Physiology 1978; 45: 637-43.
16. Peyton P, Robinson G, Terry D, Junor P. A new method for measurement of gas exchange during anaesthesia using an extractable marker gas. Physiological Measurement 2004; 25: 1-14.
17. Robinson G, Peyton P, Terry D, Malekzadeh S, Thompson B. Continuous measurement of gas uptake and elimination in anesthetized patients using an extractable marker gas. Journal of Applied Physiology 2004; 97: 960-6.
18. Korman B, Mapleson WW. Concentration and second gas effects: Can the accepted explanation be improved? British Journal of Anaesthesia 1997; 78: 618-25.
19. Mapleson WW, Korman B. Concentration and second gas effects in the water analogue. British Journal of Anaesthesia 1998; 81: 837-43.
20. Severinghaus JW. The rate of uptake of nitrous oxide in man. Journal of Clinical Investigation 1954; 33: 1183.
21. Nunn JF. Factors influencing the arterial oxygen tension during halothane anesthesia with spontaneous ventilation. British Journal of Anaesthesia 1964; 36: 327-41.
22. Nunn JF, Berman NA, Coleman AJ. Factors influencing the arterial oxygen tension during anesthesia with artificial ventilation. British Journal of Anaesthesia 1965; 37: 898-914.
23. 2. Anaesthesia 1967; 22: 69.
24. Hess W, Kannmacher J, Kruse J. Contamination of anaesthetic gases with nitric oxide and its influence on oxygenation: Study in patients undergoing open heart surgery. British Journal of Anaesthesia 2004; 93: 629-33.
25. Peyton P, Carette RM, Hendrickx JFA, et al. Contamination of anaesthetic gases with nitric oxide and its influence on oxygenation. British Journal of Anaesthesia 2005; 94: 687-8.