Cross-presentation of a human malaria CTL epitope is conformation dependent

Molecular Immunology

Volumn 43, Issue 13, 2006, Pages 2031-2036

  Prato, S ^a,b   Fleming, J ^a   Schmidt, C W ^a   Corradin, G ^b   Lopez, J A ^a  

^a ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

3D structure; Antigen presentation; Circumsporozoite protein; Malaria

Indexed keywords

CIRCUMSPOROZOITE PROTEIN; DISULFIDE; EPITOPE;

ANTIGEN PRESENTING CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL LINE; CONFORMATION; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; IN VITRO STUDY; MALARIA; NONHUMAN; OXIDATION; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

ANTIGEN PRESENTATION; ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE; DISULFIDES; EPITOPES, T-LYMPHOCYTE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; OXIDATION-REDUCTION; PEPTIDE FRAGMENTS; PROTOZOAN PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TH2 CELLS;

PLASMODIUM FALCIPARUM;

EID: 33645886332     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2005.12.014     Document Type: Article

References (25)

1. Accapezzato D., Visco V., Francavilla V., Molette C., Donato T., Paroli M., Mondelli M.U., Doria M., Torrisi M.R., and Barnaba V. Chloroquine enhances human CD8+ T cell responses against soluble antigens in vivo. J. Exp. Med. 202 (2005) 817-828
2. Ackerman A.L., Kyritsis C., Tampe R., and Cresswell P. Access of soluble antigens to the endoplasmic reticulum can explain cross-presentation by dendritic cells. Nat. Immunol. 6 (2005) 107-113
3. Bevan M.J. Cross-priming for a secondary cytotoxic response to minor H antigens with H-2 congenic cells which do not cross-react in the cytotoxic assay. J. Exp. Med. 143 (1976) 1283-1288
4. Bonelo A., Valmori D., Triponez F., Tiercy J.M., Mentha G., Oberholzer J., Champagne P., Romero J.F., Esposito F., Nebie I., Barbey C., Romero P., Herrera S., Corradin G., and Lopez J.A. Generation and characterization of malaria-specific human CD8(+) lymphocyte clones: effect of natural polymorphism on T cell recognition and endogenous cognate antigen presentation by liver cells. Eur. J. Immunol. 30 (2000) 3079-3088
5. Brossart P., and Bevan M.J. Presentation of exogenous protein antigens on major histocompatibility complex class I molecules by dendritic cells: pathway of presentation and regulation by cytokines. Blood 90 (1997) 1594-1599
6. Buchmuller Y., and Corradin G. Lymphocyte specificity to protein antigens V. Conformational dependence of activation of cytochrome c-specific T cells. Eur. J. Immunol. 12 (1982) 412-416
7. Eberl G., Renggli J., Men Y., Roggero M.A., Lopez J.A., and Corradin G. Extracellular processing and presentation of a 69-mer synthetic polypetide to MHC class I-restricted T cells. Mol. Immunol. 36 (1999) 103-112
8. Gnjatic S., Atanackovic D., Matsuo M., Jager E., Lee S.Y., Valmori D., Chen Y.T., Ritter G., Knuth A., and Old L.J. Cross-presentation of HLA class I epitopes from exogenous NY-ESO-1 polypeptides by nonprofessional APCs. J. Immunol. 170 (2003) 1191-1196
9. Griem P., Panthel K., Kalbacher H., and Gleichmann E. Alteration of a model antigen by Au(III) leads to T cell sensitization to cryptic peptides. Eur. J. Immunol. 26 (1996) 279-287
10. Guermonprez P., Saveanu L., Kleijmeer M., Davoust J., Van Endert P., and Amigorena S. ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells. Nature 425 (2003) 397-402
11. Heath W.R., Belz G.T., Behrens G.M., Smith C.M., Forehan S.P., Parish I.A., Davey G.M., Wilson N.S., Carbone F.R., and Villadangos J.A. Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens. Immunol. Rev. 199 (2004) 9-26
12. Hensmann M., Li C., Moss C., Lindo V., Greer F., Watts C., Ogun S.A., Holder A.A., and Langhorne J. Disulfide bonds in merozoite surface protein 1 of the malaria parasite impede efficient antigen processing and affect the in vivo antibody response. Eur. J. Immunol. 34 (2004) 639-648
13. Hosken N.A., and Bevan M.J. Defective presentation of endogenous antigen by a cell line expressing class I molecules. Science 248 (1990) 367-370
14. Houde M., Bertholet S., Gagnon E., Brunet S., Goyette G., Laplante A., Princiotta M.F., Thibault P., Sacks D., and Desjardins M. Phagosomes are competent organelles for antigen cross-presentation. Nature 425 (2003) 402-406
15. Hughes E.A., Ortmann B., Surman M., and Cresswell P. The protease inhibitor, N-acetyl-l-leucyl-l-leucyl-leucyl-l-norleucinal, decreases the pool of major histocompatibility complex class I-binding peptides and inhibits peptide trimming in the endoplasmic reticulum. J. Exp. Med. 183 (1996) 1569-1578
16. Michalek M.T., Grant E.P., and Rock K.L. Chemical denaturation and modification of ovalbumin alters its dependence on ubiquitin conjugation for class I antigen presentation. J. Immunol. 157 (1996) 617-624
17. Moron V.G., Rueda P., Sedlik C., and Leclerc C. In vivo, dendritic cells can cross-present virus-like particles using an endosome-to-cytosol pathway. J. Immunol. 171 (2003) 2242-2250
18. Pamer E., and Cresswell P. Mechanisms of MHC class I-restricted antigen processing. Annu. Rev. Immunol. 16 (1998) 323-358
19. Prato S., Maxwell T., Pinzon-Charry A., Schmidt C.W., Corradin G., and Lopez J.A. MHC class I-restricted exogenous presentation of a synthetic 102-mer malaria vaccine polypeptide. Eur. J. Immunol. 35 (2005) 681-689
20. Roggero M.A., Filippi B., Church P., Hoffman S.L., Blum-Tirouvanziam U., Lopez J.A., Esposito F., Matile H., Reymond C.D., Fasel N., et al. Synthesis and immunological characterization of 104-mer and 102-mer peptides corresponding to the N- and C-terminal regions of the Plasmodium falciparum CS protein. Mol. Immunol. 32 (1995) 1301-1309
21. Roggero M.A., Servis C., and Corradin G. A simple and rapid procedure for the purification of synthetic polypeptides by a combination of affinity chromatography and methionine chemistry. FEBS Lett. 408 (1997) 285-288
22. Thai R., Moine G., Desmadril M., Servent D., Tarride J.L., Menez A., and Leonetti M. Antigen stability controls antigen presentation. J. Biol. Chem. 279 (2004) 50257-50266
23. Wilson N.S., and Villadangos J.A. Regulation of antigen presentation and cross-presentation in the dendritic cell network: facts, hypothesis, and immunological implications. Adv. Immunol. 86 (2005) 241-305
24. Yewdell J.W., and Bennink J.R. Brefeldin A specifically inhibits presentation of protein antigens to cytotoxic T lymphocytes. Science 244 (1989) 1072-1075
25. Yewdell J.W., Norbury C.C., and Bennink J.R. Mechanisms of exogenous antigen presentation by MHC class I molecules in vitro and in vivo: implications for generating CD8+ T cell responses to infectious agents, tumors, transplants, and vaccines. Adv. Immunol. 73 (1999) 1-77