Cytoprotective doses of erythropoietin or carbamylated erythropoietin have markedly different procoagulant and activities

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 15, 2006, Pages 5965-5970

  Coleman, Thomas R ^a,b   Westenfelder, Christof ^c   Tögel, Florian E ^c   Yang, Ying ^c   Hu, Zhuma ^c   Swenson, LeAnne ^c   Leuvenink, Henri G D ^d   Ploeg, Rutger J ^d   D'Uscio, Livius V ^e   Katusic, Zvonimir S ^e   Ghezzi, Pietro ^a,f   Zanetti, Adriana ^f   Kaushansky, Kenneth ^g   Fox, Norma E ^g   Cerami, Anthony ^a,b   Brines, Michael ^a,b  

^a Kenneth S Warren Institute   (United States)

^b Warren Pharmaceuticals Inc   (United States)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF GRONINGEN   (Netherlands)

^e Mayo Clinic   (United States)

^f MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^g UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

common receptor; Cytokine; Hypertension; Thrombosis; Tissue protection

Indexed keywords

BETA COMMON RECEPTOR; CARBAMYLATED RECOMBINANT ERYTHROPOIETIN; CYTOKINE; ERYTHROPOIETIN RECEPTOR; HETEROMERIC ERYTHROPOIETIN RECEPTOR COMPLEX; HOMODIMERIC ERYTHROPOIETIN RECEPTOR; LIGAND; RECOMBINANT ERYTHROPOIETIN; UNCLASSIFIED DRUG;

ADOLESCENT; ADVERSE DRUG REACTION; ANIMAL TISSUE; ARTICLE; BLOOD CLOTTING; BLOOD PRESSURE; BLOOD VESSEL REACTIVITY; CANCER MORTALITY; CANCER PATIENT; CELL PROTECTION; DOSE RESPONSE; DRUG EFFECT; DRUG MEGADOSE; DRUG RECEPTOR BINDING; DRUG WITHDRAWAL; HIGH RISK POPULATION; HUMAN; HUMAN CELL; HYPERTENSION; HYPERVISCOSITY SYNDROME; INJURY; KIDNEY BLOOD FLOW; LOW DRUG DOSE; MALE; MORBIDITY; NONHUMAN; PARACRINE SIGNALING; POLYCYTHEMIA; PRIORITY JOURNAL; PROTECTION; RAT; SODIUM EXCRETION; THROMBOCYTE COUNT; THROMBOSIS; TISSUE PROTECTION;

ANIMALS; BLOOD COAGULATION; BLOOD PRESSURE; BONE MARROW CELLS; CELL LINE; COAGULANTS; ENDOTHELIUM, VASCULAR; ERYTHROPOIETIN; HEMATOPOIESIS; HEMODYNAMIC PROCESSES; HUMANS; MICE; RENAL CIRCULATION; STEM CELLS; UMBILICAL VEINS;

ANIMALIA;

EID: 33645827977     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0601377103     Document Type: Article

References (58)

1. Eschbach, J. W., Egrie, J. C., Downing, M. R., Browne, J. K. & Adamson, J. W. (1987) N. Engl. J. Med. 316, 73-78.
2. Grossman, H. A., Goon, B., Bowers, P. & Leitz, G. (2003) J. Acquired Immune Defic. Syndr. 34, 368-378.
3. Santini, D., Vincenzi, B., La Cesa, A., Virzi, V., Navajas, F., Malafarina, V., Dicuonzo, G., Cassandro, R., Esposito, V., Montesarchio, V., et al. (2005) Anticancer Res. 25, 669-674.
4. Rosenzweig, M. Q., Bender, C. M., Lucke, J. P., Yasko, J. M. & Brufsky, A. M. (2004) J. Pain Symptom Manage. 27, 185-190.
5. Leyland-Jones, B. (2003) Lancet Oncol. 4, 459-460.
6. Henke, M., Laszig, R., Rube, C., Schafer, U., Haase, K. D., Schilcher, B., Mose, S., Beer, K. T., Burger, U., Dougherty, C. & Frommhold, H. (2003) Lancet 362, 1255-1260.
7. Khorana, A. A., Francis, C. W., Culakova, E. & Lyman, G. H. (2005) Cancer 104, 2822-2829.
8. Westenfelder, C., Biddle, D. L. & Baranowski, R. L. (1999) Kidney Int. 55, 808-820.
9. Juul, S. E., Yachnis, A. T. & Christensen, R. D. (1998) Early Hum. Dev. 52, 235-249.
10. Westenfelder, C. (2002) Exp. Nephrol. 10, 294-298.
11. Brines, M. & Cerami, A. (2005) Nat. Rev. Neurosci. 6, 484-494.
12. Moon, C., Krawczyk, M., Paik, D., Lakatta, E. G. & Talan, M. I. (2005) Cardiovasc. Drugs Ther. 19, 243-250.
13. Saray, A., Ozakpinar, R., Koc, C., Serel, S., Sen, Z. & Can, Z. (2003) Laryngoscope 113, 85-89.
14. Fisher, J. W. (2003) Exp. Biol. Med. (Maywood, NJ) 228, 1-14.
15. Clyne, N., Berglund, B. & Egberg, N. (1995) Thromb. Res. 79, 125-129.
16. Stohlawetz, P. J., Dzirlo, L., Hergovich, N., Lackner, E., Mensik, C., Eichler, H. G., Kabrna, E., Geissler, K. & Jilma, B. (2000) Blood 95, 2983-2989.
17. Wolf, R. F., Peng, J., Friese, P., Gilmore, L. S., Burstein, S. A. & Dale, G. L. (1997) Thromb. Haemostasis 78, 1505-1509.
18. Tassies, D., Reverter, J. C., Cases, A., Calls, J., Escolar, G. & Ordinas, A. (1998) Am. J. Hematol. 59, 105-109.
19. Fuste, B., Serradell, M., Escolar, G., Cases, A., Mazzara, R., Castillo, R., Ordinas, A. & Diaz-Ricart, M. (2002) Thromb. Haemostasis 88, 678-685.
20. Wolf, R. F., Gilmore, L. S., Friese, P., Downs, T., Burstein, S. A. & Dale, G. L. (1997) Thromb. Haemostasis 77, 1020-1024.
21. Wun, T., Law, L., Harvey, D., Sieracki, B., Scudder, S. A. & Ryu, J. K. (2003) Cancer 98, 1514-1520.
22. Nomura, S., Nakamura, T., Cone, J., Tandon, N. N. & Kambayashi, J. (2000) Cytometry 40, 173-181.
23. Aguilera, A., Selgas, R., Ruiz-Caravaca, M. L., Bajo, M. A., Cuesta, M. V., Plaza, M. A. & Hernanz, A. (1999) Peritoneal Dialysis Int. 19, Suppl. 2, S161-S166.
24. Ando, M., Iwata, A., Ozeki, Y., Tsuchiya, K., Akiba, T. & Nihei, H. (2002) Kidney Int. 62, 1757-1763.
25. Ishikawa, A., Suzuki, K. & Fujita, K. (1999) Urol. Res. 27, 312-314.
26. Abraham, P. A. & Macres, M. G. (1991) J. Am. Soc. Nephrol. 2, 927-936.
27. Buckner, F. S., Eschbach, J. W., Haley, N. R., Davidson, R. C. & Adamson, J. W. (1990) Am. J. Hypertens. 3, 947-955.
28. Tokish, J. M., Kocher, M. S. & Hawkins, R. J. (2004) Am. J. Sports Med. 32, 1543-1553.
29. Brines, M., Grasso, G., Fiordaliso, F., Sfacteria, A., Ghezzi, P., Fratelli, M., Latini, R., Xie, Q. W., Smart, J., Su-Rick, C. J., et al. (2004) Proc. Natl. Acad. Sci. USA 101, 14907-14912.
30. Leist, M., Ghezzi, P., Grasso, G., Bianchi, R., Villa, P., Fratelli, M., Savino, C., Bianchi, M., Nielsen, J., Gerwien, J., et al. (2004) Science 305, 239-242.
31. Creutzig, A., Caspary, L., Nonnast-Daniel, B., Bahlmann, J., Kuhn, K., Brunkhorst, R., Reimers, E., Koch, K. M. & Alexander, K. (1990) Eur J. Clin. Invest. 20, 219-223.
32. Vaziri, N. D., Zhou, X. J., Smith, J., Oveisi, F., Baldwin, K. & Purdy, R. E. (1995) Am. J. Physiol. 269, F838-F845.
33. Nowicki, M. (1995) J. Hum. Hypertens. 9, 81-88.
34. Cotter, D. J., Stefanik, K., Zhang, Y., Thamer, M., Scharfstein, D. & Kaufman, J. (2004) J. Clin. Epidemiol. 57, 1086-1095.
35. Zhang, Y., Thamer, M., Stefanik, K., Kaufman, J. & Cotter, D. J. (2004) Am. J. Kidney Dis. 44, 866-876.
36. Besarab, A., Bolton, W. K., Browne, J. K., Egrie, J. C., Nissenson, A. R., Okamoto, D. M., Schwab, S. J. & Goodkin, D. A. (1998) N. Engl. J. Med. 339, 584-590.
37. Ehrenreich, H., Hasselblatt, M., Dembowski, C., Cepek, L., Lewczuk, F., Stiefel, M., Rustenbeck, H. H., Breiter, N., Jacob, S., Knerlich, F., et al. (2002) Mol. Med. 8, 495-505.
38. Gorio, A., Madaschi, L., Di Stefano, B., Carelli, S., Di Giulio, A. M., De Biasi, S., Coleman, T., Cerami, A. & Brines, M. (2005) Proc. Natl. Acad. Sci. USA 102, 16379-16384.
39. Lin, A., Ryu, J., Harvey, D., Sieracki, B., Scudder, S. & Wun, T. (2006) Gynecol. Oncol., 10.1016/j.ygyno.2005.11.031.
40. Ley, K. (1996) Cardiovasc. Res. 32, 733-742.
41. Kahraman, S., Yilmaz, R., Kirkpantur, A., Genctoy, G., Arici, M., Altun, B., Erdem, Y., Yasavul, U. & Turgan, C. (2005) Nephrology (Carlton) 10, 264-269.
42. Villa, P., Bigini, P., Mennini, T., Agnello, D., Laragione, T., Cagnotto, A., Viviani, B., Marinovich, M., Cerami, A., Coleman, T. R., et al. (2003) J. Exp. Med. 198, 971-975.
43. Carlini, R. G., Alonzo, E. J., Dominguez, J., Bianca, I., Weisinger, J. R., Rothstein, M. & Bellorin-Font, E. (1999) Kidney Int. 55, 546-553.
44. Aghi, M. & Chiocca, E. A. (2005) Mol. Ther. 6, 994-1005.
45. Byrd, N. & Grabel, L. (2004) Trends Cardiovasc. Med. 14, 308-313.
46. Yasuda, Y., Masuda, S., Chikuma, M., Inoue, K., Nagao, M. & Sasaki, R. (1998) J. Biol. Chem. 273, 25381-25387.
47. Yasuda, Y., Musha, T., Tanaka, H., Fujita, Y., Fujita, H., Utsumi, H., Matsuo, T., Masuda, S., Nagao, M., Sasaki, R. & Nakamura, Y. (2001) Br. J. Cancer 84, 836-843.
48. Jaquet, K., Krause, K., Tawakol-Khodai, M., Geidel, S. & Kuck, K. H. (2002) Microvasc. Res. 64, 326-333.
49. Hale, S. A., Wong, C. & Lounsbury, K. M. (2005) Gynecol. Oncol. 100, 14-19.
50. Huang, C., Davis, G. & Johns, E. J. (1992) Clin. Sci. (London) 83, 453-459.
51. Heidenreich, S., Rahn, K. H. & Zidek, W. (1991) Kidney Int. 39, 259-265.
52. Kanagy, N. L., Perrine, M. F., Cheung, D. K. & Walker, B. R. (2003) J. Cardiovasc. Pharmacol. 42, 527-533.
53. Ammarguellat, F., Gogusev, J. & Drueke, T. B. (1996) Nephrol. Dial. Transplant 11, 687-692.
54. Neusser, M., Tepel, M. & Zidek, W. (1993) Cardiovasc. Res. 27, 1233-1236.
55. Bunke, M., Gleason, J. R., Jr., Brier, M. & Sloan, R. (1994) Clin. Pharmacol. Ther. 55, 563-568.
56. Nushiro, N., Sakamaki, T., Hoshino, J., Nakamura, T., Sakamoto, H., Imai, Y., Seino, M., Omata, K., Sekino, H. & Abe, K. (1995) Hypertens. Res. 18, 203-207.
57. Brier, M. E., Bunke, C. M., Lathon, P. V. & Aronoff, G. R. (1993) J. Am. Soc. Nephrol. 3, 1583-1590.
58. Lampugnani, M. G., Zanetti, A., Corada, M., Takahashi, T., Balconi, G., Breviario, F., Orsenigo, F., Cattelino, A., Kemler, R., Daniel, T. O. & Dejana, E. (2003) J. Cell Biol. 161, 793-804.