Nongenomic renal effects of aldosterone: Dependency on NO and genomic actions

Hypertension

Volumn 47, Issue 4, 2006, Pages 636-637

  Chun, Tae Yon ^a   Pratt, J Howard ^a,b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; CALCIUM; CYCLIC AMP; DIACYLGLYCEROL; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ESTROGEN; INOSITOL TRISPHOSPHATE; MINERALOCORTICOID RECEPTOR; N(G) METHYLARGININE; NITRIC OXIDE; PROTEIN KINASE C; SODIUM;

CALCIUM CELL LEVEL; DISEASE MODEL; EDITORIAL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GLOMERULUS FILTRATION RATE; HEMODYNAMICS; HORMONE ACTION; HUMAN; HYPERTENSION; KIDNEY BLOOD VESSEL; OBESITY; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SODIUM ABSORPTION; VASCULAR RESISTANCE; ANIMAL; BLOOD VESSEL; DRUG EFFECT; GENOME; KIDNEY; METABOLISM; NOTE; PHYSIOLOGY; VASCULARIZATION;

ALDOSTERONE; ANIMALS; BLOOD VESSELS; GENOME; HUMANS; KIDNEY; NITRIC OXIDE; VASCULAR RESISTANCE;

EID: 33645827760     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000205225.88721.2c     Document Type: Editorial

References (12)

1. Vasan RS, Evans JC, Larson MG, Larson MG, Wilson PW, Meigs JB, Rifai N, Benjamin EJ, Levy D. Serum aldosterone and the incidence of hypertension in nonhypertensive persons. N Engl J Med. 2004;351:3-41.
2. Schmidt BMW, Sammer U, Fleischmann I, Schlaich M, Delles C, Schmieder RE. Rapid nongenomic effects of aldosterone on the renal vasculature in humans. Hypertension. 2006;47:650-655.
3. Moura AM, Worcel M. Direct action of aldosterone on transmembrane 22Na efflux from arterial smooth muscle. Rapid and delayed effects. Hypertension. 1984;6:425-430.
4. Wehling M, Kasmayr J, Theisen K. Rapid effects of mineralocorticoids on sodium-proton exchanger: genomic or nongenomic pathway? Am J Physiol. 1991;260:E719-E726.
5. Funder JW. The nongenomic actions of aldosterone. Endocr Rev. 2005;26:313-321.
6. Arima S, Kohagura K, Xu HL, Sugawara A, Uruno A, Satoh F, Takeuchi K, Ito S. Endothelium-derived nitric oxide modulates vascular action of aldosterone in renal arteriole. Hypertension. 2004;43:352-357.
7. Nishizaka MK, Zaman MA, Green SA, Renfroe KY, Calhoun DA. Impaired endothelium-dependent flow-mediated vasodilation in hypertensive subjects with hyperaldosteronism. Circulation. 2004;109:2857-2861.
8. de Paula RB, da Silva AA, Hall JE. Aldosterone antagonism attenuates obesity-induced hypertension and glomerular hyperfiltration. Hypertension. 2004;43:41-47.
9. Orshal JM, Khalil RA. Gender, sex hormones, and vascular tone. Am J Physiol Regul Integr Comp Physiol. 2004;286:R233-R249.
10. Revankar CM, Cimino DF, Sklar LA, Arterburn JB, Prossnitz ER. A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science. 2005;307:1625-1630.
11. Kousteni S, Chen JR, Bellido T, Han L, Ali AA, O'Brien CA, Plotkin L, Fu Q, Mancino AT, Wen Y, Vertino AM, Powers CC, Stewart SA, Ebert R, Parfitt AM, Weinstein RS, Jilka RL, Manolagas SC. Reversal of bone loss in mice by nongenotropic signaling of sex steroids. Science. 2002;298:843-846.
12. Michea L, Delpiano AM, Hitschfeld C, Lobos L, Lavandero S, Marusic ET. Eplerenone blocks nongenomic effects of aldosterone on the Na+/H+ exchanger, intracellular Ca2+ levels, and vasoconstriction in mesenteric resistance vessels. Endocrinology. 2005;146:973-980.