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Volumn 26, Issue 2 A, 2006, Pages 1261-1270

Evaluation of hypoxic cell radio-sensitizers in terms of radio-sensitizing and repair-inhibiting potential. Dependency on p53 status of tumor cells and the effects on intratumor quiescent cells

Author keywords

Misonidazole; Nimorazole; p53 status; Quiescent cell; Radio sensitizer; Repair inhibiting agent; SR 2514

Indexed keywords

BROXURIDINE; MISONIDAZOLE; NIMORAZOLE; PROTEIN P53; RADIOSENSITIZING AGENT;

EID: 33645812558     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (17)

References (24)
  • 2
    • 0141757504 scopus 로고    scopus 로고
    • P53 and radiation responses
    • Fei P and El-Deiry WS: P53 and radiation responses. Oncogene 22: 5774-5783, 2003.
    • (2003) Oncogene , vol.22 , pp. 5774-5783
    • Fei, P.1    El-Deiry, W.S.2
  • 5
    • 21644455492 scopus 로고    scopus 로고
    • P53 in cancer: A paradigm for modern management of cancer
    • Steele RJ and Lane DP: P53 in cancer: a paradigm for modern management of cancer. Surgeon 3: 197-205, 2005.
    • (2005) Surgeon , vol.3 , pp. 197-205
    • Steele, R.J.1    Lane, D.P.2
  • 6
    • 18144379866 scopus 로고    scopus 로고
    • TP53 mutations as biomarkers for cancer epidemiology in Latin America: Current knowledge and perspectives
    • Epub 2005 Mar 31, 2005
    • de Moura Gallo CV, Azevedo E, Silva Mendonca G, de Moraes E, Olivier M and Hainaut P: TP53 mutations as biomarkers for cancer epidemiology in Latin America: current knowledge and perspectives. Mutat Res 589: 192-207. Epub 2005 Mar 31, 2005.
    • Mutat Res , vol.589 , pp. 192-207
    • De Moura Gallo, C.V.1    Azevedo, E.2    Silva Mendonca, G.3    De Moraes, E.4    Olivier, M.5    Hainaut, P.6
  • 7
    • 0042871531 scopus 로고    scopus 로고
    • Significance of the response of quiescent cell populations within solid tumors in cancer therapy
    • Masunaga S and Ono K: Significance of the response of quiescent cell populations within solid tumors in cancer therapy. J Radiat Res 43: 11-25, 2003.
    • (2003) J Radiat Res , vol.43 , pp. 11-25
    • Masunaga, S.1    Ono, K.2
  • 8
    • 0034193202 scopus 로고    scopus 로고
    • Transfection with mutant p53 gene inhibits heat-induced apoptosis in a head and neck cell line of human squamous cell carcinoma
    • Ota I, Ohnishi K, Takahashi A, Yane K, Kanata H, Miyahara H, Ohnishi T and Hosoi H: Transfection with mutant p53 gene inhibits heat-induced apoptosis in a head and neck cell line of human squamous cell carcinoma. Int J Radiat Oncol Biol Phys 47: 495-501, 2000.
    • (2000) Int J Radiat Oncol Biol Phys , vol.47 , pp. 495-501
    • Ota, I.1    Ohnishi, K.2    Takahashi, A.3    Yane, K.4    Kanata, H.5    Miyahara, H.6    Ohnishi, T.7    Hosoi, H.8
  • 9
    • 0035131428 scopus 로고    scopus 로고
    • Different inducibility of radiation- or heat-induced p53-dependent apoptosis after acute or chronic irradiation in human cultured squamous cell carcinoma cells
    • Takahashi A: Different inducibility of radiation- or heat-induced p53-dependent apoptosis after acute or chronic irradiation in human cultured squamous cell carcinoma cells. Int J Radiat Biol 77: 215-224, 2001.
    • (2001) Int J Radiat Biol , vol.77 , pp. 215-224
    • Takahashi, A.1
  • 11
    • 0032004724 scopus 로고    scopus 로고
    • Contribution of protein kinase C to p53 dependent WAF1 induction pathway after heat treatment in human glioblastoma cell lines
    • Ohnishi K, Wang X, Takahashi A and Ohnishi T: Contribution of protein kinase C to p53 dependent WAF1 induction pathway after heat treatment in human glioblastoma cell lines. Exp Cell Res 238: 399-406, 1998.
    • (1998) Exp Cell Res , vol.238 , pp. 399-406
    • Ohnishi, K.1    Wang, X.2    Takahashi, A.3    Ohnishi, T.4
  • 12
    • 0036202667 scopus 로고    scopus 로고
    • Radiobiological characteristics of solid tumours depending on the p53 status of tumour cells, with emphasis on the response of intratumour quiescent cells
    • Masunaga S, Ono K, Takahashi A, Ohnishi T, Kinashi Y and Takagaki M: Radiobiological characteristics of solid tumours depending on the p53 status of tumour cells, with emphasis on the response of intratumour quiescent cells. Eur J Cancer 38: 718-727, 2002.
    • (2002) Eur J Cancer , vol.38 , pp. 718-727
    • Masunaga, S.1    Ono, K.2    Takahashi, A.3    Ohnishi, T.4    Kinashi, Y.5    Takagaki, M.6
  • 15
    • 0024331256 scopus 로고
    • Sensitization of hypoxic tumor cells. Clinical experiences
    • Overgaard J: Sensitization of hypoxic tumor cells. Clinical experiences. Int J Radiat Biol 56: 801-811, 1989.
    • (1989) Int J Radiat Biol , vol.56 , pp. 801-811
    • Overgaard, J.1
  • 17
    • 26444467146 scopus 로고    scopus 로고
    • Danish Head and Neck Cancer Study Group: Plasma osteopontin, hypoxia, and response to the hypoxia sensitizer nimorazole in radiotherapy of head and neck cancer: Results from the DAHANCA 5 randomized double-blind placebo-controlled trial
    • Overgaard J, Eriksen JG, Nordsmark M, Aisner J and Horsman MR: Danish Head and Neck Cancer Study Group: Plasma osteopontin, hypoxia, and response to the hypoxia sensitizer nimorazole in radiotherapy of head and neck cancer: results from the DAHANCA 5 randomized double-blind placebo-controlled trial. Lancet Oncol 6: 757-764, 2005.
    • (2005) Lancet Oncol , vol.6 , pp. 757-764
    • Overgaard, J.1    Eriksen, J.G.2    Nordsmark, M.3    Aisner, J.4    Horsman, M.R.5
  • 18
    • 0034671945 scopus 로고    scopus 로고
    • Oncogenic mutations of the p53 tumor suppressor: The demons of the guardian of the genome
    • Sigal A and Rotter V: Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome. Cancer Res 60: 6788-6793, 2000.
    • (2000) Cancer Res , vol.60 , pp. 6788-6793
    • Sigal, A.1    Rotter, V.2
  • 19
    • 11844293427 scopus 로고    scopus 로고
    • P53 and prognosis: New insights and further complexity
    • Vousden KH and Prives C: P53 and prognosis: new insights and further complexity. Cell 120: 7-10, 2005.
    • (2005) Cell , vol.120 , pp. 7-10
    • Vousden, K.H.1    Prives, C.2
  • 21
    • 0038146962 scopus 로고    scopus 로고
    • ATR/ATM targets are phosphorylated by ATR in response to hypoxia and ATM in response to reoxygenation
    • Hammond EM, Dorie MJ and Giaccia AJ: ATR/ATM targets are phosphorylated by ATR in response to hypoxia and ATM in response to reoxygenation. J Biol Chem 278: 12207-12213, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 12207-12213
    • Hammond, E.M.1    Dorie, M.J.2    Giaccia, A.J.3
  • 22
    • 18144367783 scopus 로고    scopus 로고
    • p53 mutation heterogeneity in cancer
    • Soussi T and Lozano G: p53 mutation heterogeneity in cancer. Biochem Biophys Res Commun 331: 834-842, 2005.
    • (2005) Biochem Biophys Res Commun , vol.331 , pp. 834-842
    • Soussi, T.1    Lozano, G.2
  • 23
    • 0032053823 scopus 로고    scopus 로고
    • The unique physiology of solid tumors: Opportunities (and problems) for cancer therapy
    • Brown JM and Giaccia AJ: The unique physiology of solid tumors: opportunities (and problems) for cancer therapy. Cancer Res 58: 1408-1416, 1998.
    • (1998) Cancer Res , vol.58 , pp. 1408-1416
    • Brown, J.M.1    Giaccia, A.J.2
  • 24
    • 0034743861 scopus 로고    scopus 로고
    • Oxygenation status of malignant tumors: Pathogenesis of hypoxia and significance for tumor therapy
    • Vaupel P, Kelleher DK and Hoeckel M: Oxygenation status of malignant tumors: pathogenesis of hypoxia and significance for tumor therapy. Semin Oncol 28(Suppl 8): 29-35, 2001.
    • (2001) Semin Oncol , vol.28 , Issue.SUPPL. 8 , pp. 29-35
    • Vaupel, P.1    Kelleher, D.K.2    Hoeckel, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.