Galectin-1 induces chemokine production and proliferation in pancreatic stellate cells

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 290, Issue 4, 2006, Pages

  Masamune, Atsushi ^a   Satoh, Masahiro ^a   Hirabayashi, Jun ^b   Kasai, Kenichi ^c   Satoh, Kennichi ^a   Shimosegawa, Tooru ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^c TEIKYO UNIVERSITY   (Japan)

Author keywords

Galectin; Pancreatic fibrosis; Pancreatitis

Indexed keywords

BETA GALACTOSIDE; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; GALACTOSE; GALECTIN 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; PHOSPHOSPECIFIC ANTIBODY; PROTEIN KINASE B; RECOMBINANT PROTEIN; STRESS ACTIVATED PROTEIN KINASE; THIODIGALACTOSE; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL ACTIVATION; CELL CULTURE; CELL ISOLATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; EXAMINATION; FUNCTIONAL ASSESSMENT; GEL MOBILITY SHIFT ASSAY; IMMUNOFLUORESCENCE TEST; NONHUMAN; PANCREAS CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STELLATE CELL; WESTERN BLOTTING;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CHEMOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; GALECTIN 1; HUMANS; MALE; PANCREAS; RATS; RATS, WISTAR; RECOMBINANT PROTEINS;

EID: 33645802401     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00511.2005     Document Type: Article

References (53)

1. Adams L, Scott GK, and Weinberg CS. Biphasic modulation of cell growth by recombinant human galectin-1. Biochim Biophys Acta 1312: 137-144, 1996.
2. Apte MV, Haber PS, Applegate TL, Norton ID, McCaughan GW, Korsten MA, Pirola RC, and Wilson JS. Periacinar stellate shaped cells in rat pancreas: identification, isolation and culture. Gut 43: 128-133, 1998.
3. Apte MV, Haber PS, Darby SJ, Rodgers SC, McCaughan GW, Korsten MA, Pirola RC, and Wilson JS. Pancreatic stellate cells are activated by proinflammatory cytokines: implications for pancreatic fibrogenesis. Gut 44: 534-541, 1999.
4. Apte MV, Park S, Phillips PA, Santucci N, Goldstein D, Kumar RK, Ramm GA, Buchler M, Friess H, McCarroll JA, Keogh G, Merrett N, Pirola R, and Wilson JS. Desmoplastic reaction in pancreatic cancer: role of pancreatic stellate cells. Pancreas 29: 179-187, 2004.
5. Bachem MG, Schneider E, Gross H, Weidenbach H, Schmidt RM, Menke A, Siech M, Beger H, Grunert A, and Adler G. Identification, culture, and characterization of pancreatic stellate cells in rats and humans. Gastroenterology 115: 421-432, 1998.
6. Bachem MG, Schunemann M, Ramadani M, Siech M, Beger H, Buck A, Zhou S, Schmid-Kotsas A, and Adler G. Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells. Gastroenterology 128: 907-921, 2005.
7. Balkwill F and Coussens LM. Cancer: an inflammatory link. Nature 431: 405-406, 2004.
8. Barondes SH, Castronovo V, Cooper DN, Cummings RD, Drickamer K, Feizi T, Gitt MA, Hirabayashi J, Hughes C, Kasai K, Leffler H, Liu F, Lian R, Mercurio AM, Monsigny M, Piuai S, Poirer F, Raz A, Rigby PWJ, Rini JM, and Wang JL. Galectins: a family of animal beta-galactoside-binding lectins. Cell 76: 597-598, 1994.
9. Baum LG, Seilhamer JJ, Pang M, Levine WB, Beynon D, and Berliner JA. Synthesis of an endogeneous lectin, galectin-1, by human endothelial cells is up-regulated by endothelial cell activation. Glycoconj J 12: 63-68, 1995.
10. Berberat PO, Friess H, Wang L, Zhu Z, Bley T, Frigeri L, Zimmermann A, and Buchler MW. Comparative analysis of galectins in primary tumors and tumor metastasis in human pancreatic cancer. J Histochem Cytochem 49: 539-549, 2001.
11. Fitzner B, Walzel H, Sparmann G, Emmrich J, Liebe S, and Jaster R. Galectin-1 is an inductor of pancreatic stellate cell activation. Cell Signal 7: 1240-1247, 2005.
12. Fuertes MB, Molinero LL, Toscano MA, Ilarregui JM, Rubinstein N, Fainboim L, Zwirner NW, and Rabinovich GA. Regulated expression of galectin-1 during T-cell activation involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase and p70S6 kinase. Mol Cell Biochem 267: 177-185, 2004.
13. Haber PS, Keogh GW, Apte MV, Moran CS, Stewart NL, Crawford DH, Pirola RC, McCaughan GW, Ramm GA, and Wilson JS. Activation of pancreatic stellate cells in human and experimental pancreatic fibrosis. Am J Pathol 155: 1087-1095, 1999.
14. He J and Baum LG. Presentation of galectin-1 by extracellular matrix triggers T cell death. J Biol Chem 279: 4705-4712, 2004.
15. Hirabayashi J, Hashidate T, Arata Y, Nishi N, Nakamura T, Hirashima M, Urashima T, Oka T, Futai M, Muller WE, Yagi F, and Kasai K. Oligosaccharide specificity of galectins: a search by frontal affinity chromatography. Biochim Biophys Acta 1572: 232-254, 2002.
16. Hirabayashi J and Kasai K. Effect of amino acid substitution by sited-directed mutagenesis on the carbohydrate recognition and stability of human 14-kDa beta-galactoside-binding lectin. J Biol Chem 266: 23648-23653, 1991.
17. Hsu DK and Liu FT. Regulation of cellular homeostasis by galectins. Glycoconj J 19: 507-515, 2004.
18. Hughes RC. Secretion of the galectin family of mammalian carbohydrate-binding proteins. Biochim Biophys Acta 1473: 172-185, 1999.
19. La M, Cao TV, Cerchiaro G, Chilton K, Hirabayashi J, Kasai K, Oliani SM, Chernajovsky Y, and Perretti M. A novel biological activity for galectin-1: inhibition of leukocyte-endothelial cell interactions in experimental inflammation. Am J Pathol 163: 1505-1515, 2003.
20. Lin EY and Pollard JW. Role of infiltrated leucocytes in tumour growth and spread. Br J Cancer 90: 2053-2058, 2004.
21. Maeda N, Kawada N, Seki S, Arakawa T, Ikeda K, Iwao H, Okuyama H, Hirabayashi J, Kasai K, and Yoshizato K. Stimulation of proliferation of rat hepatic stellate cells by galectin-1 and galectin-3 through different intracellular signaling pathways. J Biol Chem 278: 18938-18944, 2003.
22. Masamune A, Igarashi Y, and Hakomori S. Regulatory role of ceramide in interleukin (IL)-1 beta-induced E-selectin expression in human umbilical vein endothelial cells. J Biol Chem 271: 9368-9375, 1996.
23. Masamune A, Kikuta K, Satoh M, Kume K, and Shimosegawa T. Differential roles of signaling pathways for proliferation and migration of rat pancreatic stellate cells. Tohoku J Exp Med 199: 69-84, 2003.
24. Masamune A, Kikuta K, Satoh M, Sakai Y, Satoh A, and Shimosegawa T. Ligands of peroxisome proliferator-activated receptor-gamma block activation of pancreatic stellate cells. J Biol Chem 277: 141-147, 2002.
25. Masamune A, Kikuta K, Satoh M, Satoh K, and Shimosegawa T. Rho kinase inhibitors block activation of pancreatic stellate cells. Br J Pharmacol 140: 1292-1302, 2003.
26. Masamune A, Kikuta K, Satoh M, Suzuki N, and Shimosegawa T. Protease-activated receptor-2-mediated proliferation and collagen production of rat pancreatic stellate cells. J Pharmacol Exp Ther 312: 651-658, 2005.
27. 2H)-one] blocks activation of pancreatic stellate cells. J Pharmacol Exp Ther 310: 520-527, 2004.
28. Masamune A, Sakai Y, Kikuta K, Satoh M, Satoh A, and Shimosegawa T. Activated rat pancreatic stellate cells express intercellular adhesion molecule-1 (ICAM-1) in vitro. Pancreas 25: 78-85, 2002.
29. Masamune A, Satoh M, Kikuta K, Sakai Y, Satoh A, and Shimosegawa T. Inhibition of p38 mitogen-activated protein kinase blocks activation of rat pancreatic stellate cells. J Pharmacol Exp Ther 304: 8-14, 2003.
30. Masamune A, Satoh M, Kikuta K, Suzuki N, Satoh K, and Shimosegawa T. Ellagic acid blocks activation of pancreatic stellate cells. Biochem Pharmacol 70: 869-878, 2005.
31. Moiseeva EP, Javed Q, Spring EL, and de Bono DP. Galectin 1 is involved in vascular smooth muscle cell proliferation. Cardiovasc Res 45: 493-502, 2000.
32. Moiseeva EP, Williams B, Goodall AH, and Samani NJ. Galectin-1 interacts with beta-1 subunit of integrin. Biochem Biophys Res Commun 310: 1010-1016, 2003.
33. Ozeki Y, Matsui T, Yamamoto Y, Funahashi M, Hamako J, and Titani K. Tissue fibronectin is an endogenous ligand for galectin-1. Glycobiology 5: 255-261, 1995.
34. Perillo NL, Marcus ME, and Baum LG. Galectins: versatile modulators of cell adhesion, cell proliferation, and cell death. J Mol Med 76: 402-412, 1998.
35. Perillo NL, Pace KE, Seilhamer JJ, and Baum LG. Apoptosis of T cells mediated by galectin-1. Nature 378: 736-739, 1995.
36. Pierce JW, Schoenleber R, Jesmok G, Best J, Moore SA, Collins T, and Gerritsen ME. Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo. J Biol Chem 272: 21096-21103, 1997.
37. Rabinovich GA. Galectin-1 as a potential cancer target. Br J Cancer 92: 1188-1192, 2005.
38. Rabinovich GA, Ariel A, Hershkoviz R, Hirabayashi J, Kasai KI, and Lider O. Specific inhibition of T-cell adhesion to extracellular matrix and proinflammatory cytokine secretion by human recombinant galectin-1. Immunology 97: 100-106, 1999.
39. Rabinovich GA, Baum LG, Tinari N, Paganelli R, Natoli C, Liu FT, and Iacobelli S. Galectins and their ligands: amplifiers, silencers or tuners of the inflammatory response? Trends Immunol 23: 313-320, 2002.
40. Rabinovich G, Castagna L, Landa C, Riera CM, and Sotomayor C. Regulated expression of a 16-kd galectin-like protein in activated rat macrophages. J Leukoc Biol 59: 363-370, 1996.
41. Rabinovich GA, Daly G, Dreja H, Tailor H, Riera CM, Hirabayashi J, and Chernajovsky Y. Recombinant galectin-1 and its genetic delivery suppress collagen-induced arthritis via T cell apoptosis. J Exp Med 190: 385-398, 1999.
42. Sanford GL and Harris-Hooker S. Stimulation of vascular cell proliferation by β-galactoside-specific lectins. FASEB J 4: 2912-2918, 1990.
43. Santucci L, Fiorucci S, Rubinstein N, Mencarelli A, Palazzetti B, Federici B, Rabinovich GA, and Morelli A. Galectin-1 suppresses experimental colitis in mice. Gastroenterology 124: 1381-1394, 2003.
44. Schneider E, Schmid-Kotsas A, Zhao J, Weidenbach H, Schmid RM, Menke A, Adler G, Waltenberger J, Grunert A, and Bachem MG. Identification of mediators stimulating proliferation and matrix synthesis of rat pancreatic stellate cells. Am J Physiol Cell Physiol 281: C532-C543, 2001.
45. Scott K and Weinberg C. Galectin-1: a bifunctional regulator of cellular proliferation. Glycoconj J 19: 467-477, 2004.
46. Sgroi D, Varki A, Braesch-Andersen S, and Stamenkovic I. CD22, a B cell-specific immunoglobulin superfamily member, is a sialic acid-binding lectin. J Biol Chem 268: 7011-7018, 1993.
47. Shen J, Person MD, Zhu J, Abbruzzese JL, and Li D. Protein expression profiles in pancreatic adenocarcinoma compared with normal pancreatic tissue and tissue affected by pancreatitis as detected by two-dimensional gel electrophoresis and mass spectrometry. Cancer Res 64: 9018-9026, 2004.
48. Van den Brule F, Califice S, Garnier F, Fernandez PL, Berchuck A, and Castronovo V. Galectin-1 accumulation in the ovary carcinoma peritumoral stroma is induced by ovary carcinoma cells and affects both cancer cell proliferation and adhesion to laminin-1 and fibronectin. Lab Invest 83: 377-386, 2003.
49. Van den Brule FA, Waltregny D, and Castronovo V. Increased expression of galectin-1 in carcinoma-associated stroma predicts poor outcome in prostate carcinoma patients. J Pathol 193: 80-87, 2001.
50. Wang L, Friess H, Zhu Z, Frigeri L, Zimmermann A, Korc M, Berberat PO, and Buchler MW. Galectin-1 and galectin-3 in chronic pancreatitis. Lab Invest 80: 1233-1241, 2000.
51. Wells V and Mallucci L. Identification of an autocrine negative growth factor: mouse beta-galactoside-binding protein is a cytostatic factor and cell growth regulator. Cell 64: 91-97, 1991.
52. Yamaoka K, Mishima K, Nagashima Y, Asai A, Sanai Y, and Kirino T. Expression of galectin-1 mRNA correlates with the malignant potential of human gliomas and expression of antisense galectin-1 inhibits the growth of 9 glioma cells. J Neurosci Res 59: 722-730, 2000.
53. Zhou Q and Cummings RD. The S-type lectin from calf heart tissue binds selectively to the carbohydrate chains of laminin. Arch Biochem Biophys 281: 27-35, 1990.