Defect of oral tolerance in NC/Nga mice

Journal of Medical Investigation

Volumn 53, Issue 1-2, 2006, Pages 29-33

  Sakai, Tohru ^a,b   Kogiso, Mari ^a   Mitsuya, Kaori ^a   Komatsu, Tatushi ^b   Yamamoto, Shigeru ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b Osaka City University   (Japan)

Author keywords

Antibody; Antigen; NC Nga mice; Oral tolerance; Ovalbumin

Indexed keywords

CASEIN; FOOD ANTIGEN; OVALBUMIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; DRUG INHIBITION; IMMUNIZATION; IMMUNOLOGICAL TOLERANCE; MOUSE; MOUSE STRAIN; NONHUMAN; T LYMPHOCYTE;

ADMINISTRATION, ORAL; ANIMALS; ANTIGENS; CASEINS; DERMATITIS, ATOPIC; HUMANS; IMMUNE TOLERANCE; IMMUNOGLOBULIN G; MICE; MICE, INBRED BALB C; MODELS, IMMUNOLOGICAL; OVALBUMIN; T-LYMPHOCYTES;

ANIMALIA;

EID: 33645799108     PISSN: 13431420     EISSN: None     Source Type: Journal    
DOI: 10.2152/jmi.53.29     Document Type: Article

References (21)

1. Garza KM, Chan VS, Ohashi PS: T cell tolerance and autoimmunity. Rev Immunogenet 2: 2-17, 2000
2. Akdis CA, Joss A, Akdis M, Blaser K: Mechanisms of IL-10-induced T cell inactivation in allergic inflammation and normal response to allergens. Int Arch Allergy Immunol 124: 180-182, 2001
3. Yu X, Carpenter P, Anasetti C: Advances in transplantation tolerance. Lancet 357: 1959-1963, 2001
4. Weiner HL: Oral tolerance: Immune mechanisms and the generation of Th3-type TGF-beta-secreting regulatory cells. Microbes and Infect 3: 947-954, 2001
5. Black PN: Does atopy protect against enteric infection? Allergy 60: 30-34, 2005
6. Uehara M, Kimura C: Descendant family history of atopic dermatitis. Acta Dermatol Venereol 73: 62-63, 1993
7. Van Bever HP: Recent advances in the pathogenesis of atopic dermatitis. Eur J Pediatr 151: 870-873, 1992
8. Matsuda H, Watanabe N, Geba GP, Sperl J, Tsudzuki M, Hiro J, Matsumoto M, Ushio H, Saito S, Askenase PW, Ra C: Development of atopic dermatitis-like skin lesion with IgE hyperproduction in NC/Nga mice. Int Immunol 9: 461-466, 1997
9. Matsumoto M, Ra C, Kawamoto K, Sato H, Itakura A, Sawada J, Ushio H, Suto H, Mitsuishi K, Hikasa Y, Matsuda H: IgE hyperproduction through enhanced tyrosine phosphorylation of Janus kinase 3 in NC/Nga mice, a model for human atopic dermatitis. J Immunol 162: 1056-1063, 1999
10. Vestergaard C, Yoneyama H, Murai M, Nakamura K, Tamaki K, Terashima Y, Imai T, Yoshie O, Irimura T, Mizutani H, Matsushima K: Overproduction of Th 2-specific chemokines in NC/Nga mice exhibiting atopic dermatitis-like lesions. J Clin Invest 104: 1097-1105, 1999
11. Faria AMC, Weiner HL: Oral tolerance: mechanisms and therapeutic applications. Adv Immunol 73: 153-264, 1999
12. +T cells in major histocompatibility complex class II-deficient mice. Science 253: 1417-1420, 1991
13. Melamed D, Fishman-Lovell J, Uni Z, Weiner HL, Friedman A: Peripheral tolerance of Th2 lymphocytes induced by continuous feeding of ovalbumin. Int Immunol 8: 717-724, 1996
14. Hoyne GF, Thomas WR: T cell responses to orally administered antigens: study of the kinetics of lymphokine production after single and multiple feeding. Immunology 84: 304-309, 1995
15. Garside P, Steel M, Worthey EA, Satoskar A Alexander J, Bluethmann H, Liew FY, Mowat AM: T helper 2 cells are subject to high dose oral tolerance and are not essential for its induction. J Immunol 154: 5649-5655, 1995
16. Melamed D, Friedman A: In vivo tolerization of Th 1 lymphocytes following a single feeding with ovalbumin: anergy in the absence of suppression. Eur J Immunol 24: 1974-1981, 1994
17. +regulatory T cells by oral antigen administration. J Immunol 167: 4245-4253, 2001
18. +CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen. J Immunol 167: 188-195, 2001
19. Matsumoto M, Itakura A, Tanaka A, Fujisawa C, Matsuda H: Inhibitory of IL-12 to down-regulate IgE synthesis due to defective production of IFN-γ in atopic NC/Nga mice. J Immunol 167: 5955-5962, 2001
20. Takai T: Roles of Fc receptors in autoimmunity. Nature Rev Immunol 2: 580-592, 2002
21. Jiang Y, Hirose S, Abe M, Sanokawa-Akakura R, Ohtsuji M, Mi X, Li N, Xiu Y, Zhang D, Shirai J, Hamano Y, Fujii H, Shirai T: Polymorphisms in IgG Fc receptor IIB regulatory regions associated with autoimmune susceptibility. Immunogenetics 51: 429-435, 2000