Elevation of serum cerebral injury markers correlates with serum choline decline after coronary artery bypass grafting surgery

Clinical Chemistry and Laboratory Medicine

Volumn 44, Issue 4, 2006, Pages 471-478

  Ilcol, Yesim Ozarda ^a   Basagan Mogol, Elif ^a   Cengiz, Mete ^a   Ulus, Ismail H ^a  

^a ULUDAG UNIVERSITY   (Turkey)

Author keywords

Brain injury; Cognitive decline; Coronary artery surgery; Free choline; Neuron specific enolase (NSE); S 100

Indexed keywords

BIOLOGICAL MARKER; CHOLINE; NEURON SPECIFIC ENOLASE; PHOSPHOLIPID; PROTEIN S100B;

ADULT; AGED; ARTICLE; BLOOD ANALYSIS; BRAIN INJURY; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; CORRELATION ANALYSIS; DISEASE ASSOCIATION; ENZYME BLOOD LEVEL; FEMALE; HUMAN; MALE; MENTAL DETERIORATION; OFF PUMP CORONARY SURGERY; POSTOPERATIVE COMPLICATION; POSTOPERATIVE PERIOD; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; UPREGULATION;

ADULT; AGED; BIOLOGICAL MARKERS; BRAIN DISEASES; CHOLINE; COGNITION DISORDERS; CORONARY ARTERY BYPASS; FEMALE; HUMANS; MALE; MIDDLE AGED; NERVE GROWTH FACTORS; PHOSPHOPYRUVATE HYDRATASE; S100 PROTEINS; TIME FACTORS;

EID: 33645795517     PISSN: 14346621     EISSN: 14346621     Source Type: Journal    
DOI: 10.1515/CCLM.2006.074     Document Type: Article

References (53)

1. Wurtman RJ. Choline metabolism as a basis for the selective vulnerability of cholinergic neurons. Trends Neurosci 1992;15:117-22.
2. Löffelholz K, Klein J, Köppen A. Choline: a precursor of acetylcholine and phospholipids in the brain. Prog Brain Res 1993; 98:197-200.
3. Zeisel SH. Choline: an essential nutrient for humans. Nutrition 2000;16:669-71.
4. Ikarashi Y, Takayashi A, Ishimaru H, Maruyama Y. Striatal extracellular choline and acetylcholine in choline-free plasma rats. Brain Res Bull 1994;34:359-63.
5. Buyukuysal RL, Ulus IH, Aydin S, Kiran BK. 3,4-Diaminopyridine and choline increase in vivo acetylcholine release in rat striatum. Eur J Pharmacol 1995;281:179-85.
6. Köppen A, Klein J, Erb C, Löffelholz K. Acetylcholine release and choline availability in rat hippocampus: effects of exogenous choline and nicotinamide. J Pharmacol Exp Ther 1997;282:1139-45.
7. Kopf SR, Buchholzer ML, Hilgert M, Löffelholz K, Klein J. Glucose plus choline improve passive avoidance behaviour and increase hippocampal acetylcholine release in mice. Neuroscience 2001;103:365-71.
8. Nakamura A, Suzuki Y, Umegaki H, Ikari H, Tajima T, Endo H, et al. Dietary restriction of choline reduces hippocampal acetylcholine release in rats: in vivo microdialysis study. Brain Res Bull 2001;56:593-7.
9. Ulus IH, Wurtman RJ. Choline administration: activation of tyrosine hydroxylase in dopaminergic neurons of rat brain. Science 1976;194:1060-1.
10. Cohen BM, Renshaw PF, Stoll AL, Wurtman RJ, Yurgelun-Todd D, Babb SM. Decreased brain choline uptake in older adults. An in vivo proton magnetic resonance spectroscopy study. J Am Med Assoc 1995;274:902-7.
11. Klein J, Köppen A, Löffelholz K. Uptake and storage of choline by rat brain: influence of dietary choline supplementation. J Neurochem 1991;57:370-5.
12. Klein J, Köppen A, Löffelholz K. Regulation of free choline in brain: dietary and pharmacological manipulations. Neurochem Int 1998;32:479-85.
13. Stoll AL, Renshaw PF, DeMicheli E, Wurtman RJ, Cohen BM. Choline ingestion increases the resonance of choline-containing compounds in human brain. Biol Psychiatry 1995;37:170-4.
14. Buchman AL, Sohel M, Brown M, Jenden DJ, Ahn C, Roch M, et al. Verbal and visual memory improve after choline supplementation in long-term total parenteral nutrition: a pilot study. J Parenter Enteral Nutr 2001;25:30-5.
15. Wurtman RJ, Regan M, Ulus IH, Yu L. Effect of oral CDP-choline on plasma choline and uridine levels in humans. Biochem Pharmacol 2000;60:989-92.
16. Guo-Ross SX, Clark S, Montoya DA, Jones KH, Obernier J, Shetty AK, et al. Prenatal choline supplementation protects against postnatal neurotoxicity. J Neurosci 2001;21:195.
17. Holmes GL, Yang Y, Liu Z, Cermak JM, Sarkisian MR, Stafstrom CE, et al. Seizure-induced memory impairment is reduced by choline supplementation before or after status epilepticus. Epilepsy Res 2002;48:3-13.
18. Ulus IH, Ozyurt G, Korfali E. Decreased serum choline concentrations in humans after surgery, childbirth, and traumatic head injury. Neurochem Res 1998;23:727-32.
19. Ilcol YO, Ozyurt G, Kilicturgay S, Uncu G, Ulus IH. The decline in serum choline concentration in humans during and after surgery is associated with the elevation of cortisol, adrenocorticotropic hormone, prolactin and β-endorphin concentrations. Neurosci Lett 2002;324:41-4.
20. Ilcol YO, Uncu G, Goren S, Sayan E, Ulus IH. Declines in serum free and bound choline concentrations in humans after three different types of major surgery. Clin Chem Lab Med 2004;42:1390-5.
21. Van Dijk D, Jansen EW, Hijman R, Nierich AP, Diephuis JC, Moons KG, et al. Cognitive outcome after off-pump and on-pump coronary artery bypass graft surgery. A randomized trial. J Am Med Assoc 2002;287:1405-12.
22. Stroobant N, Van Nooten G, Belleghem Y, Vingerhoets G. Short-term and long-term neurocognitive outcome in on-pump versus off-pump CABG. Eur J Cardiothorac Surg 2002;22:559-64.
23. Zamvar V, Williams D, Hall J, Payne N, Cann C, Young K, et al. Assessment of neurocognitive impairment after off-pump and on-pump techniques for coronary bypass graft surgery: prospective randomized controlled trial. Br Med J 2002;325:1268-72.
24. Selnes OA, McKhann GM. Neurocognitive complications after coronary artery bypass surgery. Ann Neurol 2005;57:615-21.
25. Fodale V, Santamaria LB. Drugs of anaesthesia, central nicotinic receptors and post-operative cognitive dysfunction. Acta Anaesthesiol Scand 2003;47:1180.
26. Fodale V, Santamaria LB. The inhibition of central nicotinic nAch receptors is the possible cause of prolonged cognitive impairment after anesthesia. Anesth Analg 2003;97:1207.
27. Everitt BJ, Robbins TW. Central cholinergic system and cognition. Annu Rev Psychol 1997;48:649-84.
28. Perry E. Cholinergic mechanisms and cognitive decline. Eur J Anaesthesiol 1998;15:768-73.
29. Rasmussen LS, Christiansen M, Eliasen K, Sander-Jensen K, Moller JT. Biochemical markers for brain damage after cardiac surgery - time profile and correlation with cognitive dysfunction. Acta Anaesthesiol Scand 2002;46:547-51.
30. Rasmussen LS, Christiansen M, Hansen PB, Moller JT. Do blood levels of neuron-specific enolase and S-100 protein reflect cognitive dysfunction after coronary artery bypass? Acta Anaesthesiol Scand 1999;43:495-500.
31. Lindstedt U, Meyer O, Kropp P, Berkau A, Tapp E, Zenz M. Serum concentration of S-100 protein in assessment of cognitive dysfunction after general anesthesia in different types of surgery. Acta Anaesthesiol Scand 2002;46:384-9.
32. Wang FL, Haubrich DL. A simple, sensitive and specific assay for free choline in plasma. Anal Biochem 1975;63:195-201.
33. Takayama M, Itoh S, Nagasaki T, Tanimizu I. A new enzymatic method for determination of serum choline-containing phospholipids. Clin Chim Acta 1977;79:93-8.
34. Ilcol YO, Ozbek R, Hamurtekin E, Ulus IH. Choline status in newborn, infants, children, breast-feeding women, breast-fed infants and human breast milk. J Nutritional Biochem 2005;16:489-99.
35. Diegeler A, Doll N, Rauch T, Haberer D, Walther T, Falk V, et al. Humoral immune response during coronary artery bypass grafting. A comparison of limited approach, "off-pump" technique, and conventional cardiopulmonary bypass. Circulation 2000;102(Suppl III):III95-100.
36. Yamaguchi A, Endo H, Kawahito K, Adachi H, Ino T. Off-pump coronary artery bypass grafting attenuates proinflammatory markers. Jpn J Thorac Cardiovasc Surg 2005;53:127-32.
37. Gerritsen WB, van Boven WJ, Driessen AH, Haas FJ, Aarts LP. On-pump versus off-pump coronary artery bypass grafting: oxidative stress and renal function. Eur J Cardiothorac Surg 2001;20:923-9.
38. Ilcol YO, Yilmaz Z, Ulus IH. Serum free and phospholipid-bound choline decrease after surgery and methylprednisolone administration in dogs. Neurosci Lett 2003;339:195-8.
39. Savendahl L, Mar MH, Underwood LE, Zeisel SH. Prolonged fasting in humans results in diminished plasma choline concentrations but does not cause liver dysfunction Am J Clin Nutr 1997;66:622-5.
40. Canived JL, Damas P, Buret J, Lamy M. Postoperative changes in lipid profile: their relations with inflammatory markers and endocrine mediators. Acta Anaesthesiol Belg 1998;15:768-73.
41. Anderson RE, Hansson LO, Vaage J. Release of S100B during coronary artery bypass grafting is reduced by off-pump surgery. Ann Thorac Surg 1999;67:1721-5.
42. Wandschneider W, Thalmann M, Trampitsch E, Ziervogel G, Kobinia G. Off-pump coronary bypass operations significantly reduce S100 release: an indicator for less cerebral damage. Ann Thorac Surg 2000;70:1577-9.
43. Ishida K, Gohara T, Kawata R, Ohtake K, Morimoto Y, Sakabe T. Are serum S100β protein and neuron-specific enolase predictors of cerebral damage in cardiovascular surgery? J Cardiothorac Vasc Anesth 2003;17:4-9.
44. Jönsson H, Johnsson P, Högland P, Ailing C, Blomquist S. The elimination of S100B and renal function after cardiac surgery. Cardiothorac Vasc Anesth 2000;14:698-701.
45. Klein J, Köppen A, Löffelholz K. Small rises in plasma choline reverse the negative arteriovenous difference of brain choline. J Neurochem 1990;55:1231-6.
46. Klein J, Köppen A, Löffelholz K, Schmitthenner J. Uptake and metabolism of choline by rat brain after acute choline administration. J Neurochem 1992;58:870-6.
47. Ulus IH, Wurtman RJ, Mauron C, Blusztajn JK. Choline increases acetylcholine release and protects against the stimulation-induced decrease in phosphatide levels within membranes of rat corpus striatum. Brain Res 1989;484:217-27.
48. Rasmussen LS, Larsen K, Houx P, Skovgaard LT, Hanning CD, Moller JT. The assessment of postoperative cognitive function. Acta Anaesthesiol Scand 2001;45:275-89.
49. Derkach DN, Okamoto H, Takahashi S. Neuronal and astroglial injuries in patients undergoing coronary artery bypass grafting and aortic arch replacement during hypothermic cardiopulmonary bypass. Anesth Analg 2000;91:1066-72.
50. Buchman AL, Jenden DJ, Moukarzel AA, Roch M, Rice KM, Chang AS, et al. Choline pharmacokinetics during intermittent intravenous choline infusion in human subjects. Clin Pharmacol Ther 1994;55:277-83.
51. Dodds C, Allison J. Postoperative cognitive deficit in the elderly surgical patients. Br J Anaesth 1998;81:449-62.
52. Spiers PA, Myers D, Hochanadel GS, Lieberman HR, Wurtman RJ. Citicoline improves verbal memory in aging. Arch Neurol 1996;53:441-8.
53. Dixon CE, Ma X, Marion DW. Effects of CDP-choline treatment on neurobehavioral deficits after TBI and on hippocampal and neocortical acetylcholine release. J Neurotauma 1997;14:161-9.