Synthesis of spirastrellolide A fragments for structure elucidation

Synlett

Volumn , Issue 6, 2006, Pages 853-856

  Pan, Yue ^a   De Brabander, Jef K ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Asymmetric synthesis; Natural products; Spiro compounds; Structure elucidation; Total synthesis

Indexed keywords

ACETONE; ALDEHYDE; ANTIMITOTIC AGENT; SPIRASTRELLOLIDE A; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; PROTON NUCLEAR MAGNETIC RESONANCE; SPECTROSCOPY; STEREOCHEMISTRY;

EID: 33645793830     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-933144     Document Type: Article

References (31)

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31. 22 fragment is potentially available from degradation of the natural product. At this point, we have not yet contacted the isolation group to explore the possibility for such degradation studies on very limited amounts of natural spirastrellolide.