Efficient synthesis of β2-amino acid by homologation of α-amino acids involving the reformatsky reaction and Mannich-type imminium electrophile

Journal of Organic Chemistry

Volumn 71, Issue 8, 2006, Pages 3332-3334

  Moumne, Roba ^a,b   Lavielle, Solange ^a   Karoyan, Philippe ^a  

^a Centre National de la Recherche Scientifique   (France)

^b Senn Chemicals AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ORGANIC POLYMERS; POLYPEPTIDES; SYNTHESIS (CHEMICAL);

HOMOLOGATION; MANNICH-TYPE IMMINIUM ELECTROPHILES; REFORMATSKY REACTION;

AMINO ACIDS;

ALPHA AMINO ACID; IMINE; IMINIUM TRIFLUOROACETATE; PEPTIDE DERIVATIVE; POLYMER; TRIFLUOROACETIC ACID; UNCLASSIFIED DRUG; AMINO ACID; BROMINE; ESTER; FLUOROACETIC ACID; MANNICH BASE; QUATERNARY AMMONIUM DERIVATIVE;

AQUEOUS SOLUTION; ARTICLE; COLUMN CHROMATOGRAPHY; DEBENZYLATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOSELECTIVITY; EVAPORATION; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; REFORMATSKY REACTION; ROOM TEMPERATURE; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS; AMINATION; CHEMICAL STRUCTURE; CHEMISTRY; ELECTRON; METHYLATION; STEREOISOMERISM; SYNTHESIS;

AMINATION; AMINO ACIDS; BROMINE; ELECTRONS; ESTERS; FLUOROACETATES; MANNICH BASES; METHYLATION; MOLECULAR STRUCTURE; QUATERNARY AMMONIUM COMPOUNDS; STEREOISOMERISM;

EID: 33645793011     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo060316a     Document Type: Article

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