Novel ketomethylene inhibitors of angiotensin I-converting enzyme (ACE): Inhibition and molecular modelling

Biological Chemistry

Volumn 387, Issue 4, 2006, Pages 461-466

  Redelinghuys, Pierre ^a   Nchinda, Aloysius T ^a   Chibale, Kelly ^a   Sturrock, Edward D ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

Kinetics; Molecular modelling; Physicochemical characterisation; Protease

Indexed keywords

AROMATIC COMPOUND; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; KETOMETHYLENE; LISINOPRIL; TRYPTOPHAN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; DRUG DESIGN; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME STRUCTURE; HUMAN; MOLECULAR MODEL; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; COMPUTER SIMULATION; HUMANS; KINETICS; MODELS, MOLECULAR; PEPTIDYL-DIPEPTIDASE A; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33645780902     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2006.061     Document Type: Article

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