Application of novel chitosan derivatives in dissolution enhancement of a poorly water soluble drug

Pharmazie

Volumn 61, Issue 4, 2006, Pages 306-311

  Aideh, Khaled M ^a   Al Khatib, H ^a   Taha, M O ^a   Al Zoubi, N ^b  

^a UNIVERSITY OF JORDAN   (Jordan)

^b APPLIED SCIENCE PRIVATE UNIVERSITY   (Jordan)

Author keywords

[No Author keywords available]

Indexed keywords

CHITOSAN DERIVATIVE; CHITOSAN PHTHALATE; CHITOSAN SUCCINATE; DEXAMETHASONE; MICROSPHERE; POLYMER; UNCLASSIFIED DRUG; WATER;

ARTICLE; CRYSTAL STRUCTURE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG RELEASE; DRUG SOLUBILITY; ENCAPSULATION; HYDROPHOBICITY; INFRARED SPECTROSCOPY; POWDER; SPRAY DRYING; SYNTHESIS; X RAY POWDER DIFFRACTION;

ALGORITHMS; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; CHITOSAN; DEXAMETHASONE; DIFFUSION; EXCIPIENTS; MICROSPHERES; PARTICLE SIZE; PHARMACEUTICAL PREPARATIONS; PHTHALIC ACIDS; POLYMERS; SOLUBILITY; SPECTROPHOTOMETRY, INFRARED; SUCCINATES; X-RAY DIFFRACTION;

EID: 33645775767     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Aiedeh K, Taha MO (2001) Synthesis of iron-crosslinked chitosan succinate and iron-crosslinked hydroxamated chitosan succinate and their in vitro evaluation as potential matrix materials for oral theophylline sustained-release beads. Eur J Pharm Sci 13: 159-168.
2. Aiedeh K, Taha M (1999) Synthesis of chitosan succinate and chitosan phthalate and their evaluation as suggested matrices in orally administered, colon-specific drug delivery systems. Arch Pharm 332: 103-107.
3. Aiedeh K, Orienti I, Bertasi V, Zecchi V (1998) Chitosan and chitosan linked to triethylene glycol glutarate or betaine as tabletting excipients for the sustained release of indomethacin. S.T.P. Pharm Sci 8: 291-296.
4. Alexeev VL, Kelberg EA, Evmenenko GA, Bronnikov SV (2000) Improvement of the mechanical properties of chitosan films by the addition of poly(ethylene oxide). Polym Eng Sci 40: 1211-1215.
5. Angelova N, Hunkeler D (1999) Rationalizing the design of polymeric biomaterials. Trends Biotechnol 17: 409-420.
6. Aral C, Akbuga J (1998) Alternative approach to the preparation of chitosan beads. Int J Pharm 168: 9-15.
7. Bhardwaj TR, Kanwar M, Lal R, Gupta A (2000) Natural gums and modified natural gums as sustained-release carriers. Drug Dev Ind Pharm 26: 1025-1038.
8. Dong Y, Ruan Y, Wang H, Zhao Y, Bi D (2004) Studies on glass transition temperature of chitosan with four techniques. J Appl Polym Sci 93: 1553-1558.
9. Heras A, Rodriguez NM, Ramos VM, Agullo E (2000) N-Methylene phosphonic chitosan: a novel soluble derivative. Carbohydr Polym 44, 1-8.
10. Illum L, Watts P, Fisher AN, Gill IJ, Davis SS (2000) Novel chitosan-based delivery systems for the nasal administration of a LHRH-analog. S.T.P. Pharm Sci 10: 89-94.
11. Kotze AF, Luessen HL, De Boer AG, Verhoef JC, Junginger HE (1999a) Chitosan for enhanced intestinal permeability: Prospects for derivatives soluble in neutral and basic environments. Eur J Pharm Sci 7: 145-151.
12. Kotze AF, Thanou MM, Luessen HL, De Boer BG, Verhoef JC, Junginger HE (1999b) Effect of the degree of quaternization of N-trimethyl chitosan chloride on the permeability of intestinal epithelial cells (Caco-2). Eur J Pharm Biopharm 47: 269-274.
13. Lehr CM, Bouwstra JA, Schacht EH, Junginger HE (1992) In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers. Int J Pharm 78: 43-48.
14. No HK, Lee KS, Meyers SP (2000) Correlation between physicochemical characteristics and binding capacities of chitosan products. J Food Sci 65: 1134-1137.
15. Pavanetto F, Genta I, Ginchedi P, Conti B (1994) Spray-dried albumin microspheres for intra-articular delivery of dexamethasone. J Microencapsul 11: 445-454.
16. Pavanetto F, Genta I, Ginchedi P, Conti B (1993) Evaluation of spray-drying as a method for polylactide and polylactide-co-glycolide microsphere preparation J. Microencapsul 10: 487-494.
17. Rege PR, Shukla DJ, Block LH (1999) Chitinosans as tableting excipients for modified release delivery systems. Int J Pharm. 181: 49-60.
18. Remunan-Lopez C, Bodmeier R (1996) Effect of formulation and process variables on the formation of chitosan-gelatin coacervates. Int J Pharm 135: 63-72.
19. Sakurai K, Maegawa T, Takahashi T (2000) Glass transition temperature of chitosan and miscibility of chitosan/poly(N-vinyl pyrrohdone) blends. Polymer 41: 7051-7056
20. Swartz SL, Dluhy RG (1978) Corticosteroids: clinical pharmacology and therapeutic use. Drugs 16: 238-255.
21. Taha MO, Aiedeh K, Amro B (2000) An investigation on the suitability of chitosan-triethyleneglycol-phthalate as a matrix in prolonged-release, orally administered, chlorpheniramine maleate granules. S.T.P. Pharm Sci 10: 395-400.
22. Thanou MM, Verhoef JC, Romeijn SG, Nagelkerke JF, Merkus WM, Junginger HE (1999) Effects of N-trimethylchitosan chloride, a novel absorption enhancer, on Caco-2 intestinal epithelia and the ciliary beat frequency of chicken embryo trachea. Int J Pharm 185: 73-82.
23. Thanou M, Nihot MT, Jansen M, Verhoef JC, Junginger HE (2001) Mono-N-carboxymethyl chitosan (MCC), a polyampholytic chitosan derivative, enhances the intestinal absorption of low molecular weight heparin across intestinal epithelia in vitro and in vivo. J Pharm Sci 90: 38-46.