The NOD2 3020insC mutation in women with breast cancer from the Bydgoszcz Region in Poland. First results

Hereditary Cancer in Clinical Practice

Volumn 4, Issue 1, 2006, Pages 15-19

  Janiszewska, Hanna ^a   Haus, Olga ^a   Lauda Świeciak, Anna ^a   Ba̧k, Aneta ^a   Mierzwa, Tomasz ^b   Sir, Jan ^b   Laskowski, Ryszard ^b  

^a NICOLAUS COPERNICUS UNIVERSITY   (Poland)

^b Oncology Center   (Poland)

Author keywords

Breast cancer; NOD2 gene mutation

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; DNA;

ADULT; AGE; AGED; ALLELE; ARTICLE; BREAST CANCER; CONTROLLED STUDY; CROHN DISEASE; DISEASE ASSOCIATION; FAMILY HISTORY; FEMALE; FRAMESHIFT MUTATION; GENE; GENE MUTATION; HUMAN; MAJOR CLINICAL STUDY; PEDIGREE; POLAND; POLYMERASE CHAIN REACTION;

EID: 33645746281     PISSN: 17312302     EISSN: None     Source Type: Journal    
DOI: 10.1186/1897-4287-4-1-15     Document Type: Article

References (9)

1. Hugot JR Laurent-Puig P, Gower-Rousseau C, Olson JM, Lee JC, Beaugerie L, Naom I, Dupas JL, Van Gossum A, Orholm M, Bonaiti-Pellie C, Weissenbach J, Mathew CG, Lennard-Jones JE, Cortot A, Colombel JF and Thomas G. Mapping of a susceptibility locus for Crohn's disease on chromosome 16. Nature 1996; 379: 821-823.
2. Inohara N and Nuòez G. NODs: intracellular proteins involved in inflammation and apoptosis. Nat Rev Immunol 2003; 3: 371-382.
3. Ogura Y, Bonen DK, Inohara N, Nicolae DL, Chen FF, Ramos R, Britton H, Moran T, Karaliuskas R, Duerr RH, Achkar JP, Brant SR, Bayless TM, Kirschner BS, Hanauer SB, Nuòez G, Cho JH. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001; 411: 603-606.
4. Hampe J, Cuthbert A, Croucher PJ, Mirza MM, Mascheretti S, Fisher S, Frenzel H, King K, Hasselmeyer A, MacPherson AJ, Bridger S, van Deventer S, Forbes A, Nikolaus S, Lennard-Jones JE, Foelsch UR, Krawczak M, Lewis C, Schreiber S and Mathew CG. Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations. Lancet 2001; 357: 1925-1928.
5. Russell RK, Nimmo ER, Satsangi J. Molecular genetics of Crohn's disease. Curr Opin Genet Dev 2004; 14: 264-270.
6. Kurzawski G, Suchy J, Kladny J, Grabowska E, Mierzejewski M, Jakubowska A, Debniak T, Cybulski C, Kowalska E, Szych Z, Domagala W, Scott RJ and Lubinski J. The NOD2 3020insC mutation and the risk of colorectal cancer. Cancer Res 2004; 64: 1604-1606.
7. Lubiński J, Huzarski T, Kurzawski G, Suchy J, Masojć B, Mierzejewski M, Lener M, Domagała W, Chosia M, Teodorczyk U, Mȩdrek K, Dȩbniak T, Złowocka E, Gronwald J, Byrski T, Grabowska E, Nej K, Szymańska A, Szymańska J, Matyjasik J, Cybulski C, Jakubowska A, Górski B and Narod S. The 3020insC allele of NOD2 predisposes to cancer of multiple organs. Hered Cancer Clin Practice 2005; 3: 59-63.
8. Huzarski T, Lener M, Domagala W, Gronwald J, Byrski T, Kurzawski G, Suchy J, Chosia M, Woyton J, Ucinski M, Narod SA and Lubinski J. The 3020insC allele of NOD2 predisposes to early-onset breast cancer. Breast Cancer Res Treat 2005; 89: 91-93.
9. Debniak T, Kurzawski G, Huzarski T, Byrski T, Gronwald J, Debniak B, Rozmiarek A, Dziuba I, Zlowocka E, Suchy J, Gorski B, Cybulski C, Mierzejewski M, Masojc B, Medrek K, Oszurek O and Lubinski J. NOD2 variants and the risk of malignant melanoma. Eur J Cancer Prev 2005; 14: 143-146.