Sex-specific differences in cerebral arterial myogenic tone in hypertensive and normotensive rats

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 290, Issue 3, 2006, Pages

  Ibrahim, Jamila ^a,b,c   McGee, Ann ^b   Graham, Delyth ^a   McGrath, John C ^b   Dominiczak, Anna F ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Blood flow; Blood pressure; Distensibility; Elastic modulus; Stroke prone spontaneously hypertensive rats; Wistar Kyoto rats

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTERY DIAMETER; ARTICLE; BLOOD PRESSURE; BODY WEIGHT; BRAIN BLOOD VESSEL; CONTROLLED STUDY; FEMALE; HYPERTENSION; MALE; MIDDLE CEREBRAL ARTERY; NONHUMAN; PRIORITY JOURNAL; RAT; RIGIDITY; SEX DIFFERENCE; STRESS STRAIN RELATIONSHIP; YOUNG MODULUS; ADRENERGIC SYSTEM; ANIMAL; BLOOD FLOW VELOCITY; BRAIN ARTERY; COMPARATIVE STUDY; ELASTICITY; MECHANICAL STRESS; PATHOPHYSIOLOGY; WISTAR KYOTO RAT;

ANIMALS; BLOOD FLOW VELOCITY; BLOOD PRESSURE; CEREBRAL ARTERIES; ELASTICITY; FEMALE; HYPERTENSION; MALE; RATS; RATS, INBRED WKY; SEX FACTORS; STRESS, MECHANICAL; VASOMOTOR SYSTEM;

EID: 33645740619     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00752.2005     Document Type: Article

References (44)

1. Alkayed NJ, Harukuni I, Kimes AS, London ED, Traystman RJ, and Hurn PD. Gender-linked brain injury in experimental stroke. Stroke 29: 159-165, 1998.
2. Baumbach GL and Heistad DD. Remodeling of cerebral arterioles in chronic hypertension. Hypertension 13: 968-972, 1989.
3. Briones AM, Gonzales JM, Somoza B, Giraldo J, Daly CJ, Vila E, Gonzalez MC, McGrath JC, and Arribas SM. Role of elastin in spontaneously hypertensive rat small mesenteric artery remodelling. J Physiol (Lond) 552: 185-195, 2003.
4. Bryant CE, Tomlinson A, Mitchell JA, Thiemermann C, and Willoughby DA. Nitric oxide synthase in the rat fallopian tube is regulated during the oestrous cycle. J Endocrinol 146: 149-157, 1995.
5. Candolfi M, Jaita G, Zaldivar V, Zarate S, Pisera D, and Seilicovich A. Tumor necrosis factor-alpha-induced nitric oxide restrains the apoptotic response of anterior pituitary cells. Neuroendocrinology 80: 83-91, 2004.
6. Carswell HV, Anderson NH, Clark JS, Graham D, Jeffs B, Dominiczak AF, and Macrae IM. Genetic and gender influences on sensitivity to focal cerebral ischemia in the stroke-prone spontaneously hypertensive rat. Hypertension 33: 681-685, 1999.
7. Crofton JT, Share L, and Brooks DP. Pressor responsiveness to and secretion of vasopressin during the estrous cycle. Am J Physiol Regul Integr Comp Physiol 255: R1041-R1048, 1988.
8. Dalle Lucca JJ, Adeagbo AS, and Alsip NL. Influence of oestrous cycle and pregnancy on the reactivity of the rat mesenteric vascular bed. Hum Reprod 15: 961-968, 2000.
9. Dantas AP, Franco Mdo C, Silva-Antonialli MM, Tostes RC, Fortes ZB, Nigro D, and Carvalho MH. Gender differences in superoxide generation in microvessels of hypertensive rats: role of NAD(P)H-oxidase. Cardiovasc Res 61: 22-29, 2004.
10. Davidson AO, Schork N, Jaques BC, Kelman AW, Sutcliffe RG, Reid JL, and Dominiczak AF. Blood pressure in genetically hypertensive rats. Influence of the Y chromosome. Hypertension 26: 452-459, 1995.
11. Dickinson CJ. Why are strokes related to hypertension? Classic studies and hypotheses revisited. J Hypertens 19: 1515-1521, 2001.
12. Dominiczak AF and McBride MW. Genetics of common polygenic stroke. Nat Genet 35: 116-117, 2003.
13. Dowell FJ, Martin W, Dominiczak AF, and Hamilton CA. Decreased basal despite enhanced agonist-stimulated effects of nitric oxide in 12-week-old stroke-prone spontaneously hypertensive rat. Eur J Pharmacol 379: 175-182, 1999.
14. Duckles SP, Krause DN, and Miller VM. Effects of gonadal steroids on vascular function. J Pharmacol Exp Ther 279: 1-3, 1996.
15. Dunn WR, Wallis SJ, and Gardiner SM. Remodelling and enhanced myogenic tone in cerebral resistance arteries isolated from genetically hypertensive Brattleboro rats. J Vasc Res 35: 18-26, 1998.
16. Garg UC and Hassid A. Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J Clin Invest 83: 1774-1777, 1989.
17. Geary GG, Krause DN, and Duckles SP. Estrogen reduces mouse cerebral artery tone through endothelial NOS- and cyclooxygenase-dependent mechanisms. Am J Physiol Heart Circ Physiol 279: H511-H519, 2000.
18. Hadju MA and Baumbach GL. Mechanics of large and small cerebral arteries in chronic hypertension. Am J Physiol Heart Circ Physiol 266: H1027-H1033, 1994.
19. Halpern W, Osol G, and Coy GS. Mechanical behaviour of pressurized in vitro prearterial vessels determined with a video system. Ann Biomed Eng 12: 463-479, 1984.
20. Harder DR, Smeda J, and Lombard J. Enhanced myogenic depolarization in hypertensive cerebral arterial muscle. Circ Res 57: 319-322, 1985.
21. Heagerty AM, Aalkjaer C, Bund SJ, Korsgard N, and Mulvany MJ. Small artery structure in hypertension. Dual processes of remodeling and growth. Hypertension 21: 391-397, 1993.
22. Hughes JM and Bund SJ. Arterial myogenic properties of the spontaneously hypertensive rat. Exp Physiol 87: 527-534, 2002.
23. Izzard AS, Graham D, Burnham MP, Heerkens EH, Dominiczak AF, and Heagerty AM. Myogenic and structural properties of cerebral arteries from the stroke-prone spontaneously hypertensive rat. Am J Physiol Heart Circ Physiol 285: H1489-H1494, 2003.
24. Jeffs B, Clark JS, Anderson NH, Gratton J, Brosnan MJ, Gauguier D, Reid JL, Macrae IM, and Dominiczak AF. Sensitivity to cerebral ischemic insult in a rat model of stroke is determined by a single genetic locus. Nat Genet 16: 364-367, 1997.
25. Lee RM, Nagahama M, McKenzie R, and Daniel EE. Peptide-containing nerves around blood vessels of stroke-prone spontaneously hypertensive rats. Hypertension 11: I117-I120, 1988.
26. Mangiarua EL and Lee RMKW. Morphometric study of cerebral arteries from spontaneously hypertensive and stroke-prone spontaneously hypertensive rats. J Hypertens 10: 1183-1190, 1992.
27. McBride MW, Carswell HV, Graham D, Carr FJ, Charchar FJ, Macrae IM, and Dominiczak AF. Genetic and gender determinants of cerebrovascular disease. Semin Nephrol 22: 127-134, 2002.
28. McGill JK, Gallagher L, Carswell HV, Irving EA, Dominiczak AF, and Macrae IM. Impaired functional recovery after stroke in the stroke-prone spontaneously hypertensive rat. Stroke 36: 135-141, 2005.
29. Minoves N, Balfagon G, and Ferrer M. Role of female sex hormones in neuronal nitric oxide release and metabolism in rat mesenteric arteries. Clin Sci (Lond) 103: 239-247, 2002.
30. i in vascular smooth muscle cells of female rat. Am J Physiol Cell Physiol 278: C834-C844, 2000.
31. Ono H, Sasaki Y, Bamba E, Seki J, Giddings JC, and Yamamoto J. Cerebral thrombosis and microcirculation of the rat during the oestrous cycle and after ovariectomy. Clin Exp Pharmacol Physiol 29: 73-78, 2002.
32. Osol G and Halpern W. Myogenic properties of cerebral blood vessels from normotensive and hypertensive rats. Am J Physiol Heart Circ Physiol 249: H914-H921, 1985.
33. Paulson OB, Strandgaard S, and Edwinsson L. Cerebral autoregulation. Cerebrovasc Brain Metab Rev 2: 161-192, 1990.
34. Schubert R and Mulvany MJ. The myogenic response: established facts and attractive hypotheses. Clin Sci (Lond) 96: 313-326, 1999.
35. Scotland RS, Chauhan S, Davis C, De Felipe C, Hunt S, Kabir J, Kotsonis P, Oh U, and Ahluwalia A. Vanilloid receptor TRPV1, sensory C-fibers, and vascular autoregulation: a novel mechanism involved in myogenic constriction. Circ Res 95: 1027-1034, 2004.
36. Skarsgard P, van Breemen C, and Laher I. Estrogen regulates myogenic tone in pressurized cerebral arteries by enhanced basal release of nitric oxide. Am J Physiol Heart Circ Physiol 273: H2248-H2256, 1997.
37. Smeda JS and Payne GW. Alterations in autoregulatory and myogenic function in the cerebrovasculature of Dahl salt-sensitive rats. Stroke 34: 1484-1490, 2003.
38. Smeda JS, VanVliet BN, and King SR. Stroke-prone spontaneously hypertensive rats lose their ability to auto-regulate cerebral blood flow prior to stroke. J Hypertens 17: 1697-1705, 1999.
39. Stier CT Jr, Benter IF, Ahmad S, Zuo H, Selig N, Roethel S, Levine S, and Itskovitz HD. Enalapril prevents stroke and kidney dysfunction in salt-loaded stroke-prone spontaneously hypertensive rats. Hypertension 13: 115-121, 1989.
40. Vacher E, Richer C, and Giudicelli JF. Effects of losartan on cerebral arteries in stroke-prone spontaneously hypertensive rats. J Hypertens 14: 1341-1348, 1996.
41. Weiner CP, Lizosoain I, Bayliss SA, Knowles RG, Charles IG, and Moncada S. Induction of calcium-dependent nitric oxide synthases by sex hormones. Proc Natl Acad Sci USA 91: 5212-5216, 1994.
42. + channels. Circ Res 79: 1024-1030, 1996.
43. Yamori Y, Horie R, Handa H, Sato M, and Fukase M. Pathogenic similarity of strokes in stroke prone spontaneously hypertensive rats and humans. Stroke 7: 46-53, 1976.
44. Zamorano B, Bruzzone ME, and Martinez JL. Influence of the estrous cycle on the norepinephrine-induced contraction of rat aorta: relationship to vascular prostanoids biosynthesis. Biol Res 27: 209-215, 1994.