메뉴 건너뛰기




Volumn 5, Issue 7, 2006, Pages 718-721

Role of the TRF2 telomeric protein in cancer and ageing

Author keywords

Aging; Cancer; Mouse models; Telomere binding proteins; Telomeres; TRF2

Indexed keywords

DNA POLYMERASE; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; NUCLEASE; REPETITIVE DNA; TELOMERASE; TELOMERIC REPEAT BINDING FACTOR 2;

EID: 33645710018     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.5.7.2636     Document Type: Review
Times cited : (59)

References (19)
  • 1
    • 0037148277 scopus 로고    scopus 로고
    • Protection of mammalian telomeres
    • De Lange T. Protection of mammalian telomeres. Oncogene 2002; 21:532-40.
    • (2002) Oncogene , vol.21 , pp. 532-540
    • De Lange, T.1
  • 2
    • 0035929353 scopus 로고    scopus 로고
    • Switching and signaling at the telomere
    • Blackburn EH. Switching and signaling at the telomere. Cell 2001; 106:661-73.
    • (2001) Cell , vol.106 , pp. 661-673
    • Blackburn, E.H.1
  • 3
    • 24944460598 scopus 로고    scopus 로고
    • Shelterin: The protein complex that shapes and safeguards human telomeres
    • de Lange T. Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev 2005; 19:2100-10.
    • (2005) Genes Dev , vol.19 , pp. 2100-2110
    • De Lange, T.1
  • 5
    • 1842424729 scopus 로고    scopus 로고
    • Resolution of sister telomere association is required for progression through mitosis
    • Dynek JN and Smith S. Resolution of sister telomere association is required for progression through mitosis. Science 2004; 304:97-100.
    • (2004) Science , vol.304 , pp. 97-100
    • Dynek, J.N.1    Smith, S.2
  • 6
    • 22844437452 scopus 로고    scopus 로고
    • The telomere repeat binding protein Trf1 interacts with the spindle checkpoint protein Mad1 and Nek2 mitotic kinase
    • Prime G, and Markie D. The telomere repeat binding protein Trf1 interacts with the spindle checkpoint protein Mad1 and Nek2 mitotic kinase. Cell Cycle 2005; 4:121-4.
    • (2005) Cell Cycle , vol.4 , pp. 121-124
    • Prime, G.1    Markie, D.2
  • 7
    • 22944488871 scopus 로고    scopus 로고
    • Telomeres and human disease: Cancer, ageing and beyond
    • Blasco MA. Telomeres and human disease: cancer, ageing and beyond. Nature Reviews Genetics 2005; 6:611-22.
    • (2005) Nature Reviews Genetics , vol.6 , pp. 611-622
    • Blasco, M.A.1
  • 8
    • 27144515686 scopus 로고    scopus 로고
    • XPF nuclease-dependent telomere loss and increased DNA damage in mice overexpressing TRF2 result in premature aging and cancer
    • Muñoz P, Blanco R, Flores JM and Blasco MA. XPF nuclease-dependent telomere loss and increased DNA damage in mice overexpressing TRF2 result in premature aging and cancer. Nature Genetics 2005;10:1063-71.
    • (2005) Nature Genetics , vol.10 , pp. 1063-1071
    • Muñoz, P.1    Blanco, R.2    Flores, J.M.3    Blasco, M.A.4
  • 9
    • 0034769105 scopus 로고    scopus 로고
    • Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres
    • Samper E, Flores JM & Blasco MA. Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres. EMBO Reports 2001; 2:1-8.
    • (2001) EMBO Reports , vol.2 , pp. 1-8
    • Samper, E.1    Flores, J.M.2    Blasco, M.A.3
  • 10
    • 0033118354 scopus 로고    scopus 로고
    • Molecular mechanism of nucleotide excision repair
    • de Laat WL, Jaspers NG and Hoeijmakers JH. Molecular mechanism of nucleotide excision repair. Genes Dev 1999; 13:768-85.
    • (1999) Genes Dev , vol.13 , pp. 768-785
    • De Laat, W.L.1    Jaspers, N.G.2    Hoeijmakers, J.H.3
  • 11
    • 0347416975 scopus 로고    scopus 로고
    • ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes
    • Zhu XD, Niedernhofer L, Kuster B, Mann M, Hoeijmakers JH, de Lange T. ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes. Mol Cell 2003; 12:1489-98.
    • (2003) Mol Cell , vol.12 , pp. 1489-1498
    • Zhu, X.D.1    Niedernhofer, L.2    Kuster, B.3    Mann, M.4    Hoeijmakers, J.H.5    De Lange, T.6
  • 12
    • 0034054019 scopus 로고    scopus 로고
    • Nucleotide excision repair and human syndromes
    • de Boer J and Hoeijmakers JH. Nucleotide excision repair and human syndromes. Carcinogenesis 2000; 21:453-60.
    • (2000) Carcinogenesis , vol.21 , pp. 453-460
    • De Boer, J.1    Hoeijmakers, J.H.2
  • 13
    • 0038359431 scopus 로고    scopus 로고
    • Evolving views of telomerase and cancer
    • Blasco MA and Hahn WC. Evolving views of telomerase and cancer. Trends Cell Biol 2003; 13:289-94.
    • (2003) Trends Cell Biol , vol.13 , pp. 289-294
    • Blasco, M.A.1    Hahn, W.C.2
  • 14
    • 0343228751 scopus 로고    scopus 로고
    • Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis
    • Gonzalez-Suarez E, Samper E, Flores JM, Blasco MA. Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis. Nat Genet 2000; 26:114-7.
    • (2000) Nat Genet , vol.26 , pp. 114-117
    • Gonzalez-Suarez, E.1    Samper, E.2    Flores, J.M.3    Blasco, M.A.4
  • 16
    • 13944263628 scopus 로고    scopus 로고
    • Human telomeric protein TRF2 associates with genomic double-strand breaks as an early response to DNA damage
    • Bradshaw PS, Stavropoulos DJ and Meyn MS. Human telomeric protein TRF2 associates with genomic double-strand breaks as an early response to DNA damage. Nat Genet 2005; 37:193-7.
    • (2005) Nat Genet , vol.37 , pp. 193-197
    • Bradshaw, P.S.1    Stavropoulos, D.J.2    Meyn, M.S.3
  • 17
    • 26444602415 scopus 로고    scopus 로고
    • p16INK4a as a second effector of the telomere damage pathway
    • Jacobs JJL and de Lange T. p16INK4a as a second effector of the telomere damage pathway. Cell Cycle 2005; 4:1364-8.
    • (2005) Cell Cycle , vol.4 , pp. 1364-1368
    • Jacobs, J.J.L.1    De Lange, T.2
  • 18
    • 11144227269 scopus 로고    scopus 로고
    • Up-regulation fo telomere-binding proteins, TRF1, TRF2 and TIN2 is related to telomere shortening during human multistep heptocarcinogenesis
    • Oh B-K, Kim Y-J, Park C and Park YN. Up-regulation fo telomere-binding proteins, TRF1, TRF2 and TIN2 is related to telomere shortening during human multistep heptocarcinogenesis. Am J Pathol 2005; 166:73-80.
    • (2005) Am J Pathol , vol.166 , pp. 73-80
    • Oh, B.-K.1    Kim, Y.-J.2    Park, C.3    Park, Y.N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.