Calcitonin and related peptides;Calcitonine et peptides apparentés

EMC - Endocrinologie

Volumn 1, Issue 4, 2004, Pages 200-213

  Cohen, R ^a   Becker, K L ^b   Jullienne, A ^c  

^a AVICENNE HOSPITAL   (France)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c CENTRE VIGGO PETERSEN   (France)

Author keywords

Adrenomedullin; Amylin; Calcitonin; Calcitonin gene related peptide; Medullar thyroid carcinoma; Procrastination

Indexed keywords

EID: 33645703919     PISSN: 17425653     EISSN: 17425653     Source Type: Journal    
DOI: 10.1016/j.emcend.2004.07.001     Document Type: Short Survey

References (126)

1. Le Moullec JM, Jullienne A, Chenais J, Lasmoles F, Guliana JM, Milhaud G, et al. The complete sequence of human preprocalcitonin. FEBS Lett 1984;167:93-7.
2. Becker KL, Snider RH, Moore CF, Monoghan KG, Silva OL. Calcitonin in extrathyroidal tissues of man. Acta Endocrinol 1979;92:746-51.
3. Becker KL, Geelhoed G, O'Neill W, Monaghan KG, Snider RH, Moore CF, et al. Calcitonin in tissues of thyroidectomized monkey. Experientia 1980;36:609-10.
4. Muller B, White JC, Nylen ES, Snider RH, Becker KL, Habener JF. Ubiquitous expression of the calcitonin-i gene in multiple tissues in response to sepsis. J Clin Endocrinol Metab 2001;86:396-404.
5. Linscheid P, Seboek D, Nylen ES, Langer I, Schlatter M, Keller U, Becker KL, et al. In vitro and in vivo calcitonin-I gene expression in parenchymal cells: a novel product of human adipose tissue. Endocrinology 2003;144:5578-84.
6. Rittel W, Maier R, Brigger M, Kamber B, Riniker B, Sieber P. Structure-activity relationship of human calcitonin III. Biological activity of synthetic analogues with shortened or terminally modified peptide chains. Experientia 1976;32: 246-8.
7. Gennari C, Chierichetti SM, Vibellli C, Francini G, Maioli E, Gonelli S. Acute effects of salmon, human and porcine calcitonin on plasma calcium and cyclic AMP levels in man. Curr Ther Res 1981;30:1024-32.
8. Gnaedinger MP, Uehlinger DE, Weidmann P, Sha SG, Muff R, Born W, et al. Distinct hemodynamic and renal effects of calcitonin gene-related peptide and calcitonin in men. Am J Physiol 1989;257:E848-E854.
9. Mohamadi M, Becker KL, Bivins LE. Paradoxical effect of salmon calcitonin on serum calcium: studies in intact and thyroparathyroidectomized men and dogs. Acta Endocrinol 1975;79:700-8.
10. Zaidi M, Bax BE, Shankar VS, Moonga BS, Simon B, Alam AS, et al. Dimensional analysis of osteoclastic bone resorption and the measurement of biologically active calcitonin. Exp Physiol 1994;79:387-99.
11. Alam AS, Bax CM, Shankar VS, Bax BE, Bevis PJ, Huang CL, et al. Further studies on the mode of action of calcitonin on isolated rat osteoclasts: pharmacological evidence for a second site mediating extracellular Ca2+ mobilization and cell retraction. J Endocrinol 1993;136:7-15.
12. Moonga BS, Alam AS, Bevis PJ, Avaldi F, Soncini R, Huang CL, et al. Regulation of cytosolic free calcium in isolated rat osteoclasts by calcitonin. J Endocrinol 1992; 132:241-9.
13. Zheng MH, Fan Y, Wysocki S, Wood DJ, Papadimitriou JM. Carbonic acid anhydrase II gene transcript in cultured osteoclasts from neonatal rats: effect of calcitonin. Cell Tissue Res 1994;276:7-13.
14. Tolino A, Romano L, Ronsini S, Riccio S, Montemagno U. Treatment of postmenopausal osteoporosis with salmon calcitonin nasal spray: evaluation by bone mineral content and biochemical patterns. Int J Clin Pharmacol Ther Toxicol 1993;31:358-60.
15. Farley J, Dimai HP, Stilt-Coffing B, Farley P, Pham T, Mohan S. Calcitonin increases the concentration of insulin-like growth factors in serum-free cultures of human osteoblast-line cells. Calcif Tissue Int 2000;67:247-54.
16. Wongsuranat N, Armbrecht HJ. Calcitonin stimulates 1,25-dihydroxyvitamin D production in diabetic rat kidney. Metabolism 1991;40:22-5.
17. Beckman MJ, Goff JP, Reinhardt TA, Beitz DC, Horst RL. In vivo regulation of rat intestinal 24-hydroxylase: potential new role of calcitonin. Endocrinology 1994;135:1951-5.
18. Su KW, Matsumoto T, Takahashi H, Yamamoto M, Ogata E. Interaction of calcitonin with vitamin D and prostaglandin E2 on renal tubular reabsorption of calcium in thyroparathyroidectomized rats. Miner Electrolyte Metab 1988;14: 229-34.
19. Bucht E, Rong H, Sjoberg HE, Sjostedt U, Granberg B, Torring H. Serum calcitonin forms and concentrations in young and healthy females. Calcif Tissue Int 1995;56:32-7.
20. Chait A, Suaudeau C, De Beaurepaire R. Extensive brain mapping of calcitonin-induced anorexia. Brain Res Bull 1995;36:467-72.
21. Sellami S, de Beaurepaire R. Medial diencephalic sites involved in calcitonin-induced hyperthermia and analgesia. Brain Res 1993;616:307-10.
22. Tannenbaum GS, Goltzman D. Calcitonin gene-related peptide mimics calcitonin actions in brain on growth hormone release and feeding. Endocrinology 1985;116: 2685-7.
23. Mulder H. Calcitonin-testosterone interrelationship. A classic feedback system? Neth J Med 1993;42:209-11.
24. Chen D, Lee KH. Antinociceptive activity of calcitonin and central cholinergic system: behavioral and neurochemical analyses. Biochem Pharmacol 1995;49:1623-31.
25. Coldado ML, Ormazabal MJ, Goicoechea C, Lopez F, Alfaro MJ, Martin MI. Involvement of central serotoninergic pathways in analgesia elicited by salmon calcitonin in mouse. Eur J Pharmacol 1994;252:291-7.
26. Martin MI, Alfaro MI, Goicoechea C, Coldado MI. In vitro study of the interaction of salmon calcitonin with mu, delta, and kappa opioid agonists. Naunyn-Schmiedebergs. Arch Pharmacol 1993;347:324-8.
27. Pontiroli AE, Pajetta E, Scaglia L, Rubinacci A, Resmini G, Arrigoni M, et al. Analgesic effect of intranasal and intramuscular salmon calcitonin in post-menopausal osteoporosis: a double-blind, double-placebo study. Aging 1994;6:459-63.
28. Becker KL, Monaghan KG, Silva OL. Immunocytochemical localization of calcitonin in Kulchitsky cells of human lung. Arch Pathol Lab Med 1980;104:196-8.
29. Tabassian AR, Nylen ES, Linnoila RI, Snider RH, Cassidy MM, Becker KL. Stimulation of hamster pulmonary neuroendocrine cells and associated peptides by repeated exposure to cigarette smoke. Am Rev Respir Dis 1989;140:436-40.
30. Burch WM. Calcitonin stimulates growth and maturation of embryonic chick pelvic cartilage in vitro. Endocrinology 1984;114:1196-202.
31. Demol P, Hotz J, Muller MK, Trompeter R, Muttathil J, Goebell H. Effect of calcitonin on the interdigestive motility and on gastric and pancreatic secretion in humans. Arch Int Physiol Biochim 1986;94:331-8.
32. Gray TK, Brannan P, Juan D, Morawski G, Fordtran JS. Ion transport changes during calcitonin-induced intestinal secretion in man. Gastroenterology 1976;71:392-8.
33. Davidson A, Vermesh M, Paulson RJ, Graczykowski JW, Lobo RA. Presence of immunoreactive beta-endorphin and calcitonin in human seminal plasma, and their relation to sperm physiology. Fertil Steril 1989;51:878-80.
34. Balbanova S, Kruse B, Wolf AS. Calcitonin secretion by human placental tissue. Acta Obstet Gynecol Scand 1987; 66:323-6.
35. Ding YQ, Zhu LJ, Bagchi MK, Bagchi IC. Progesterone stimulates calcitonin gene expression in the uterus during implantation. Endocrinology 1994;135:2265-74.
36. Lafond J, Simoneau L, Savard K, Lajeunesse D. Calcitonin receptor in human placental syncytiotrophoblast brush border and basal plasma membranes. Mol Cell Endocrinol 1994;99:285-92.
37. Rebut-Bonneton C, Segond N, Demignon J, Porquet D, Evain-Brion D. Effects of calcitonin on human trophoblastic cells in culture: absence of autocrine control. Mol Cell Endocrinol 1992;85:65-71.
38. Kumar S, Zhu LJ, Polihronis M, Cameron ST, Baird DT, Schatz F, et al. Progesterone induces calcitonin gene expression in human endometrium within the putative window of implantation. J Clin Endocrinol Metab 1998;83: 4443-50.
39. Barlet JP. Calcitonin may modulate transfer of calcium in ewes. J Endocrinol 1985;104:17-21.
40. Bucht E, Sjoberg HE. Evidence for precursors of calcitonin/PDN 21 in human milk. Regul Pept 1987;19:65-71.
41. Hysing J, Gordeladze JO, Christensen G, Tolleshaug H. Renal uptake and degradation of trapped-label calcitonin. Biochem Pharmacol 1991;41:1119-26.
42. Kurokawa K. Calcium-regulating hormones and the kidney. Kidney Int 1987;32:760-71.
43. Chakraborty M, Chatterjee D, Kellokumpu S, Rasmussen H, Baron R. Cell cycle-dependent coupling of the calcitonin receptor to different G proteins. Science 1991;251:1078-82.
44. Carney SL Comparison of parathyroid hormone and calcitonin on rat renal calcium and magnesium transport. Clin Exp Pharmacol Physiol 1992;19:433-8.
45. Muff R, Kaufmann M, Born W, Fischer JA. Calcitonin inhibits phosphate intake in opossum kidney cells stably transfected with a porcine calcitonin receptor. Endocrinology 1994;134:1593-6.
46. Perry 3rd HM, Kahn AJ, Chappel JC, Kohler G, Teitelbaum SL, Peck WA. Calcitonin response in circulating human lymphocytes. Endocrinology 1983;113:1568-73.
47. Body JJ, Gilbert F, Nejai S, Fernandez G, Van Langendonck A, Borkowski A. Calcitonin receptors on circulating normal human lymphocytes. J Clin Endocrinol Metab 1990; 71:675-81.
48. Body JJ. Calcitonin: from the determination of circulating levels in various physiological and pathological conditions to the demonstration of lymphocyte receptors. Horm Res 1993;39:166-70.
49. Grieder A, Felder M, Schaffner W. Effect of salmon calcitonin on the infiltration of T lymphocytes in a synovium-like membrane of a rat inflammatory model. Agents Actions 1990;29:308-14.
50. Silva O, Wisneski LA, Cyrus J, Snider RH, Moore CF, Becker KL. Calcitonin in thyroidectomized patients. Am J Med Sci 1978;275:159-64.
51. Weissel M, Kainz H, Tyl E, Ogunyemi E, Woloszczuk W. Clinical evaluation of new assays for determination of serum calcitonin concentrations. Acta Endocrinol 1991; 124:540-4.
52. Hoff AO, Catala-Lehnen P, Thomas PM, Priemel M, Rueger JM, Nasonkin I, et al. Increased bone mass is an unexpected phenotype associated with deletion of the calcitonin gene. J Clin Invest 2002;110:1849-57.
53. Silva OL, Snider RH, Becker KL. Radioimmunoassay of calcitonin in human plasma. Clin Chem 1974;20:337-9.
54. Hurley DL, Katz HH, Tiegs RD, Calvo MS, Barta JR, Heath 3rd H. Cosecretion of calcitonin gene products: studies with a C18 cartridge extraction method for human plasma PDN-21 (katacalcin). J Clin Endocrinol Metab 1988; 66:640-4.
55. Guilloteau D, Perdrisot R, Calmettes C, Baulieu JL, Lecomte P, Kaphan G, et al. Diagnosis of medullary carcinoma of the thyroid (MCT) by calcitonin assay using monoclonal antibodies: criteria for the pentagastrin stimulation test in hereditary MCT. J Clin Endocrinol Metab 1990;71: 1064-7.
56. Body JJ, Heath 3rd H. Estimates of circulating monomeric calcitonin: physiological studies in normal and thyroidectomized man. J Clin Endocrinol Metab 1983;57:897-903.
57. Tabassian AR, Nylen ES, Giron AE, Snider RH, Cassidy MM, Becker KL. Evidence for cigarette smoke-induced calcitonin secretion from lungs of man and hamster. Life Sci 1988;42:2323-9.
58. Tabassian AR, Nylen ES, Lukacs L, Cassidy MM, Becker KL. Cholinergic regulation of hamster pulmonary neuroendocrine cell calcitonin. Exp Lung Res 1990;16:267-77.
59. Tabassian AR, Snider Jr RH, Nylen ES, Cassidy M, Becker KL. Heterogeneity studies of hamster calcitonin following acute exposure to cigarette smoke: evidence for monomeric secretion. Anat Rec 1993;236:253-6.
60. Nylen ES, Becker KL. Chronic hyperoxia and hamster pulmonary neuroendocrine cell bombesin and calcitonin. Anat Rec 1993;236:248-52.
61. Snider RH, Nylen ES, Becker KL. Procalcitonin and its component peptides in systemic inflammation: immunochemical characterization. J Invest Med 1997;45:552-60.
62. Snider RH, Silva OL, Moore CF, Becker KL. Immunochemical heterogeneity of calcitonin in man: effect on radioimmunoassay. Clin Chim Acta 1977;76:1-4.
63. Bihan H, Becker KL, Snider RH, Nylen ES, Vittaz L, Lauret C, et al. Medullary thyroid carcinoma: clinical utility of serum calcitonin precursors as a marker. Thyroid 2003;13: 819-22.
64. Perdrisot R, Bigorgne JC, Guilloteau D, Jallet P. Monoclonal immunoradiometric assay of calcitonin improves investigation of familial medullary thyroid carcinoma. Clin Chem 1990;36:381-3.
65. Seth R, Motte P, Kehely A, Wimalawansa S, Self CH, Bohuon C, et al. The development of a two-site enzyme immunometric assay (EIA) for calcitonin and its application in the measurement of the hormone in normal subjects, MCT-patients and post-menopausal women. Horm Metab Res 1989;21:3-5.
66. Motte P, Vauzelle P, Gardet P, Ghillani P, Caillou B, Parmentier C, et al. Construction and clinical validation of a sensitive and specific assay for serum mature calcitonin using monoclonal anti-peptide antibodies. Clin Chim Acta 1988;174:35-54.
67. Meisner M. Procalcitonin. Stuttgart: Georg Thieme Verlag; 2000.
68. Minvielle S, Giscard-Dartevelle S, Cohen R, Taboulet J, Labye F, Jullienne A, et al. A novel calcitonin carboxyl-terminal peptide produced in medullary thyroid carcinoma by alternative RNA processing of the calcitonin/calcitonin gene-related peptide gene. J Biol Chem 1991;266:24627-31.
69. Cohen R, Bensimon C, Raynaud A, Modigliani E. Gene-related peptide calcitonin. Actions and regulation. Ann Méd Interne 1992;143:455-62.
70. Blind E, Raue F, Klaiber T, Zink A, Schroth J, Buhr H, et al. Evaluation of sensitive PDN-21 (katacalcin) determination as tumor marker in medullary thyroid carcinoma. J Endocrinol Invest 1992;15:93-8.
71. Zaidi M, Moonga BS, Bevis PJ, Alam AS, Legon S, Wimalawansa S, et al. Expression and function of the calcitonin gene products. Vitam Horm 1991;46:87-164.
72. Cohen R, Giscard-Darteville S, Bracq S, Chanson P, Mikol J, Jullienne A, et al. Calcitonin genes (I and II) expression in human nervous and medullary thyroid carcinoma tissues. Neuropeptides 1994;26:215-9.
73. Becker KL, Nash D, Silva OL, Snider RH, Moore CF. Increased serum and urinary calcitonin levels in patients with pulmonary disease. Chest 1981;79:211-6.
74. Kelley MJ, Becker KL, Rushin JM, Venzon D, Phelps R, Ihde DC, et al. Calcitonin elevation in small cell lung cancer without ectopic production. Am J Respir Crit Care Med 1994;149:183-90.
75. Johnson MD, Gray ME, Stahlman MT. Calcitonin gene-related peptide in human fetal lung and in neonatal lung disease. J Histochem Cytochem 1988;36:199-204.
76. Linnoila RI, Becker KL, Silva OL, Snider RH, Moore CF. Calcitonin as a marker for diethylnitrosamine-induced pulmonary endocrine cell hyperplasia in hamsters. Lab Invest 1984;51:39-45.
77. Milhaud G, Tubiana M, Parmentier C, Coutris G. Epithelioma of the thyroid secreting thyrocalcitonin. C R Acad Sci Hebd Seances Acad Sci D 1968;266:608-10.
78. Redding AH, Levine SN, Fowler MR. Normal preoperative calcitonin levels do not always exclude medullary thyroid carcinoma in patients with large palpable thyroid masses. Thyroid 2000;10:919-22.
79. Cooper CW. Recent advances with thyrocalcitonin. Ann Clin Lab Sci 1976;6:119-29.
80. Barbot N, Calmettes C, Schuffenecker I, Saint-André JP, Franc B, Rohmer V, et al. Pentagastrin stimulation test and early diagnosis of medullary thyroid carcinoma using an immunoradiometric assay of calcitonin: comparison with genetic screening in hereditary medullary thyroid carcinoma. J Clin Endocrinol Metab 1994;78:114-20.
81. Barbot N, Schuffenecker I, Calmettes C, Modigliani E, Lenoir G, Bigorgne JC. Conditions actuelles du dépistage du cancer médullaire de la thyroïde. Rev Fr Endocrinol Clin 1993;34:539-48.
82. Cohen R, Quidville V, Bihan H. Medullary thyroid carcinoma and hormones. Ann Med Interne 2003;154:109-16.
83. Elisei R, Bottici V, Luchetti F, Di Coscio G, Romei C, Grasso L, et al. Impact of routine measurement of serum calcitonin on the diagnosis and outcome of medullary thyroid cancer: experience in 10,864 patients with nodular thyroid disorders. J Clin Endocrinol Metab 2004;89:163-8.
84. Modigliani E, Cohen R, Campos JM, Conte-Devolx B, Maes B, Boneu A, et al. The GETC Study Group. Groupe d'étude des tumeurs a calcitoninePrognostic factors for survival and for biochemical cure in medullary thyroid carcinoma: results in 899 patients. Clin Endocrinol 1998; 48:26573.
85. Mulligan LM, Kwok JB, Healey CS, Elsdon MJ, Eng C, Gardner E, et al. Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A. Nature 1993;363:458-60.
86. Lips CJ, Landsvater RM, Hoppener JW, Geerdink RA, Blijham G, van Veen JM, et al. Clinical screening as compared with DNA analysis in families with multiple endocrine neoplasia type 2A. N Engl J Med 1994;331:828-35.
87. Vitale G, Caraglia M, Ciccarelli A, Lupoli G, Abbruzzese A, Tagliaferri P. Current approaches and perspectives in the therapy of medullary thyroid carcinoma. Cancer 2001;91: 1797-808.
88. Saad MF, Fritsche Jr HA, Samaan NA. Diagnostic and prognostic values of carcinoembryonic antigen in medullary carcinoma of the thyroid. J Clin Endocrinol Metab 1984; 58:889-94.
89. Frendo JL, Delage-Mourroux R, Cohen R, Pichaud F, Pidoux E, Guliana JM, et al. Calcitonin receptor mRNA expression in TT cells: effect of dexamethasone. Mol Cell Endocrinol 1998;139:37-43.
90. Frendo JL, Pichaud F, Mourroux RD, Bouizar Z, Segond N, Moukhtar MS, et al. An isoform of the human calcitonin receptor is expressed in TT cells and in medullary carcinoma of the thyroid. FEBS Lett 1994;342:214-6.
91. Becker KL, Gazdar AF, Carney DN, Snider RH, Moore CF, Silva OL. Calcitonin secretion by continuous cultures of small cell carcinoma of the lung: incidence and immunoheterogeneity studies. Cancer Lett 1983;18:179-85.
92. Becker KL, Bivins LE, Radfar RH, Snider RH, Moore CF, Silva OL. Study of calcitonin heterogeneity using a radioreceptor assay. Horm Metab Res 1978;10:457-8.
93. Bertagna XY, Nicholson WE, Pettengill OS, Sorenson GD, Mount CD, Orth DN. Ectopic production of high molecular weight calcitonin and corticotrophin by human small cell carcinoma in tissue culture: evidence for separate precursors. J Clin Endocrinol Metab 1978;47:1390-3.
94. Nylen ES, Linnoila RI, Snider RH, Tabassian AR, Becker KL. Comparative studies of hamster calcitonin from pulmonary endocrine cells in vitro. Peptides 1987;8:977-82.
95. Silva OL, Broder LE, Doppman JL, Snider RH, Moore CF, Cohen MH, et al. Calcitonin as a marker for bronchogenic cancer: a prospective study. Cancer 1979;44:680-4.
96. Kelley MJ, Snider RH, Becker KL, Johnson BE. Small cell lung carcinoma cell lines express mRNA for calcitonin and alpha- and beta-calcitonin gene related peptides. Cancer Lett 1994;81:19-25.
97. Ghillani PP, Motte P, Troalen F, Jullienne A, Gardet P, Le Chevalier T, et al. Identification and measurement of calcitonin precursors in serum of patients with malignant diseases. Cancer Res 1989;49:6845-51.
98. Conlon JM, McGregor GP, Wallin G, Grimelius L, Thim L. Molecular forms of katacalcin, calcitonin gene-related peptide and gastrin-releasing peptide, in a human medullary thyroid carcinoma. Cancer Res 1988;48:2412-6.
99. Becker KL, Snider RH, Silva OL, Moore CF. Calcitonin heterogeneity in lung cancer and medullary thyroid cancer. Acta Endocrinol 1978;89:89-99.
100. Bone RC. Sepsis, sepsis syndrome and the systemic inflammatory response syndrome (SIRS). JAMA 1995;273:155-6.
101. Nylén ES, O'Neill W, Jordan MH, Snider Jr RH, Moore CF, Lewis M, et al. Serum procalcitonin as an index of inhalation injury in burns. Horm Metab Res 1992;24:439-42.
102. Assicot M, Gendrel D, Carsin H, Raymond J, Guilbaud J, Bohuon C. High serum procalcitonin concentrations in patients with sepsis and infection. Lancet 1993;341:515-8.
103. Whang KT, Steinwald PM, White JC, Nylen ES, Snider RH, Simon GL, et al. Serum calcitonin precursors in sepsis and systemic inflammation. J Clin Endocrinol Metab 1998;83: 3296-301.
104. Muller B, Becker KL, Schachinger H, Rickenbacher PR, Huber PR, Zimmerli W, et al. Calcitonin precursors are reliable markers of sepsis in a medical intensive care unit. Crit Care Med 2000;28:977-83.
105. Preas 2nd HL, Nylen ES, Snider RH, Becker KL, White JC, Agosti JM, et al. Effects of anti-inflammatory agents on serum levels of calcitonin precursors during human experimental endotoxemia. J Infect Dis 2001;184:373-6.
106. Whang KT, Vath SD, Becker KL, Snider RH, Müller B, Qichang L, et al. Procalcitonin and pro-inflammatory cytokine interactions in sepsis. Shock 2000;14:73-8.
107. Ryan CM, Yarmush ML, Burke JF, Tompkins RG. Increased gut permeability early after burns correlates with the extent of burn injury. Crit Care Med 1992;20:1508-12.
108. Nylén ES, Whang KT, Snider Jr RH, Steinwald PM, White JC, Becker KL. Mortality is increased by procalcitonin and decreased by an antiserum reactive to procalcitonin in experimental sepsis. Crit Care Med 1998;26:1001-6.
109. Wagner KE, Martinez JM, Vath SD, Snider RH, Nylen ES, Becker KL, et al. Early immunoneutralization of calcitonin precursors attenuates the adverse physiologic response to sepsis in pigs. Crit Care Med 2002;30:2313-21.
110. Martinez JM, Wagner KE, Snider RH, Nylén ES, Muller B, Sarani B, et al. Late immunoneutralization of procalcitonin arrests the progression of lethal porcine sepsis. Surg Infect 2001;2:193-203.
111. Steenbergh PH, Hoppener JW, Zandberg J, Lips CJ, Jansz HS. A second human calcitonin/CGRP gene. FEBS Lett 1985;183:403-7.
112. Wimalawansa SJ. Calcitonin gene-related peptide and its receptors: molecular genetics, physiology, pathophysiology, and therapeutic potentials. Endocr Rev 1996;17:533-85.
113. Lasmoles F, Minvielle S, Cohen R, Guliana JM, Delehaye MC, Segond N, et al. PCR amplification of CGRP II mRNA. Variable expression in tumoral and non-tumoral human thyroid. FEBS Lett 1990;277:243-6.
114. Raynaud A, Cohen R, Modigliani E. Calcitonin gene-related peptide (CGRP). Presse Méd 1994;23:171-5.
115. Cooper GJ. Amylin compared with calcitonin gene-related peptide: structure, biology, and relevance to metabolic disease. Endocr Rev 1994;15:163-201.
116. Ishimitsu T, Kojima M, Kangawa K, Hino J, Matsuoka H, Kitamura K, et al. Genomic structure of human adrenomedullin gene. Biochem Biophys Res Commun 1994;203: 631-9.
117. Castillo MJ, Scheen AJ, Lefebvre PJ. Amylin/islet amyloid polypeptide: biochemistry, physiology, patho-physiology. Diabete Metab 1995;21:3-25.
118. Kanazawa H, Kurihara N, Hirata K, Kudoh S, Kawaguchi T, Takeda T. Adrenomedullin, a newly discovered hypotensive peptide, is a potent bronchodilator. Biochem Biophys Res Commun 1994;205:251-4.
119. Hinson JP, Kapas S, Smith DM. Adrenomedullin, a multi-functional regulatory peptide. Endocr Rev 2000;21:138-67.
120. Petrie MC, Hillier C, Morton JJ, McMurray JJ. Adrenomedullin selectively inhibits angiotensin II-induced aldosterone secretion in humans. J Hypertens 2000;18:61-4.
121. Gorn AH, Lin HY, Yamin M, Auron PE, Flannery MR, Tapp DR, et al. Cloning, charaterization and expression of a human calcitonin receptor from an ovarian carcinoma cell line. J Clin Invest 1992;90:1726-35.
122. Flühmann B, Muff R, Hunziker W, Fischer JA, Born W. A human orphan calcitonin receptor-like structure. Biochem Biophys Res Commun 1995;206:341-7.
123. McLatchie LM, Fraser NJ, Main MJ, Wise A, Brown J, Thompson N, et al. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor- like receptor. Nature 1998;393:333-9.
124. Christopoulos A, Christopoulos G, Morfis M, Udawela M, Laburthe M, Couvineau A, et al. Novel receptor partners and function of receptor activity-modifying proteins. J Biol Chem 2003;278:3293-7.
125. Copp DH, Davidson AG. Evidence for a new parathyroid hormone which lowers blood calcium. Proc Soc Biol Med 1961;107:342-4.
126. Hirsch PF, Voelkel EF, Munson PL. Thyrocalcitonin: hypocalcemic hypophosphatemic principle of the thyroid gland. Science 1964;146:412-3.