Procalcitonin and its component peptides in systemic inflammation: Immunochemical characterization

Journal of Investigative Medicine

Volumn 45, Issue 9, 1997, Pages 552-560

  Snider Jr , Richard H ^a,b   Nylen, Eric S ^a   Becker, Kenneth L ^a  

^a GEORGE WASHINGTON UNIVERSITY   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Cytokine systemic inflammation; Procalcitonin; Procalcitonin aminoterminus; Sepsis; SIRS

Indexed keywords

CALCITONIN; CALCITONIN GENE RELATED PEPTIDE; DRUG DERIVATIVE; GLYCOPROTEIN; PEPTIDE FRAGMENT; PROCALCITONIN; PROTEIN PRECURSOR;

ADULT; ARTICLE; BLOOD; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; MIDDLE AGED; NEUROENDOCRINE TUMOR; PATHOLOGY; PEPTIDE MAPPING; RADIOIMMUNOASSAY; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

ADULT; CALCITONIN; CALCITONIN GENE-RELATED PEPTIDE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLYCOPROTEINS; HUMANS; MALE; MIDDLE AGED; NEUROENDOCRINE TUMORS; PEPTIDE FRAGMENTS; PEPTIDE MAPPING; PROTEIN PRECURSORS; RADIOIMMUNOASSAY; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

EID: 0031302675     PISSN: 17088267     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992;20:864-74.
2. Bone RC. Sepsis, sepsis syndrome and the systemic inflammatory response syndrome (SIRS). JAMA 1995;273:155-6.
3. Nathens AB, Marshall JC: Sepsis, SIRS, and MODS. What's in a name? World J Surg 1996;20:386-91.
4. Rangel-Frausto MS, Pittet D, Cotigan M, Hwang T. Davis CS, Wenzel RP. the natural history of the systemic inflammatory response syndrome (SIRS). A prospective study. JAMA 1995;273:117-23.
5. Lowry SF. Sepsis and its complications: Clinical definitions and therapeutic prospects. Crit Care Med 1994;20 (suppl):S1-S2.
6. Nylen ES, O'Neill W. Jordan MH, Snider RH Jr, Moore CF, Lewis M, Silva OL, Becker KL. Serum procalcitonin as an index of inhalation injury in bums. Horm Metab Res 1992;24:439-42.
7. Assicot M, Gendrel D, Carsin H. Raymond J. Guilbaud J. Bohuon C. High serum procalcitonin concentrations in patients with sepsis and infection. Lancet 1993;341:515-8.
8. Davis TME, Assicot M, Bohuon C, St John A, Li GQ, Anh TK. Serum procalcitonin concentrations in acute malaria. Trans Roy Soc Trop Med Hyg 1994;88:670-1.
9. Nylen ES, Snider RH, Thompson KA, Rohatgi P. Becker KL. Pneumonitis-associated hyperprocalcitonemia. Am J Med Sci 1996;312:12-8.
10. Nylen ES, Alarifia A, Becker KL, Snider RH, Alzeer A. The effects of classical heat stroke on serum procalcitonin. Crit Care Med 1997;25:1431-6.
11. Becker KL, Nylen, ES, Cohen R, Snider RH. Calcitonin: structure, molecular biology, and actions. In: Bilezikian JP, Raisz LG, Rodan GA, eds. Principles of bone biology. Academic Press, Inc.: San Diego 1996:471-94.
12. Jullienne A, Segond N. Calmettes C, Moukhtar MS, Milhaud G. Biosynthesis of human calcitonin: Evidence for a prohormone. Biochem Biophys Res Commun 1980;95:932-7.
13. Le Moullec JM, Jullienne A, Chenais J. Chenais J. Lasmoles F. Guliana JM, Milhaud G. Moukhtar MS. The complete sequence of human preprocalcitonin. FEBS Lett 1984;167:93-7.
14. Becker KL. The coming of age of a bronchial epithelial cell. Am Rev Resp Dis 1993;148:1166-8.
15. Eipper B A, Stoffers DA Mains RE. The biosynthesis of neuropeptides: peptide α-amidation. Annu Rev Neurosci 1992;15:57-85.
16. Arnalich F. Sanchez JF, Martinez M, Jimenez M, Lopez J. Vazquez JJ, Hernanz A. Changes in plasma concentrations of vasoactive neuropeptides in patients with sepsis and septic shock. Life Sci 1994;56:75-81.
17. Snider RH, Moore CF, Silva OL, Becker KL. Radioimmunoassay of calcitonin in normal human urine. Anal Chem 1978;50: 449-54.
18. Becker KL, Nash DR, Silva OL, Snider RH, Moore CF. Urine calcitonin levels in patients with bronchogenic carcinoma. JAMA 1980;243:670-2.
19. Becker KL, Nash D, Silva OL, Snider RH, Moore CF. Increased serum and urinary calcitonin in pulmonary disease. Chest 1981;79: 211-6.
20. Snider RH, Silva OL, Moore CF, Becker KL. Immunochemical heterogeneity of calcitonin in man: effect on radioimmunoassay. Clin Chem Acta 1977;76:1-14.
21. Becker KL, Snider RH, Silva OL, Moore CF. Calcitonin hetero-geneity in lung cancer and medullary thyroid cancer. Acta Endocrinol 1978;89:89-99.
22. Snider RH, Moore CF, Nylen ES, Becker KL. Improved HPLC separation of radiolabelled hormonal peptides. Horm Metab Res 1988;20:254-5.
23. Snider RH, Moore CF, Nylen ES, Becker KL. Prediction of peptide retention times on reverse-phase HPLC: Prospects and limitations. Bio Chromato 1988;3:100-11.
24. Becker KL, Gazdar AF, Carney DN, Snider RH, Moore CF, Silva OL. Calcitonin secretion by continuous cultures of small cell carcinoma of the lung: incidence and immunoheterogeneity studies. Cancer Lett 1983;18:179-85.
25. Kelley M, Snider R. Becker, Johnson BE. Small cell lung carcinoma cells express mRNA for calcitonin and alpha-and beta-calcitonin gene related peptides. Cancer Lett 1994;81:19-25.
26. Whang KT, Snider RH, Becker KL, Nylen ES, McDuff A, White JC. aminoproCT, the amino-terminus of procalcitonin, correlates with the progression of the systemic inflammatory response syndrome (SIRS). ICAAC, Toronto, CA, Sept. 28 1997.
27. Smith MD, Suputtamongkol Y. Chaowagul W. Assicot M, Bohuon C, Petitjean S, White NU. Elevated serum procalcitonin levels in patients with melioidosis. Clin Infect Dis 1995;20:641-5.
28. Becker KL, Steinwald P. Nylen E, White J. Snider R. Goldberg P. Whang K. Hyperprocalcitonemia as a clinical marker for systemic inflammation. ICAAC, New Orleans, LA, Sept.16, 1996.
29. Dandona P. Nix D, Wilson MF, Aljada A, Love J, Assicot M, Bohuon C. Procalcitonin increase after endotoxin injection in normal subjects. J Clin Endocrinol Metab 1994;79:1605-8.
30. Burgess TC, Kelly RB. Constitutive and regulated secretion of proteins. Annu Rev Cell Biol 1987;3 :243-93.
31. Bershadsky AD, Futerman AH. Disruption of the Golgi apparatus by brefeldin A blocks cell polarization and inhibits directed cell migration. Proc Natl Acad Sci USA 1994;91:5686-9.
32. Xu H. Shields D. Prosomatostatin processing in permeabilized cells. J Biol Chem 1994;269:22,875-881.