Supply of R-α-lipoic acid and glutamine to casein-fed mice influences the number of B lymphocytes and tissue glutathione levels during endotoxemia

Wiener Klinische Wochenschrift

Volumn 118, Issue 3-4, 2006, Pages 100-107

  Wessner, Barbara ^a   Strasser, Eva Maria ^a   Manhart, Nicole ^a   Roth, Erich ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

B lymphocytes; Endotoxemia; Glutamine; Glutathione; Lipoic acid

Indexed keywords

CASEIN; GLUTAMINE; GLUTATHIONE; LIPOPOLYSACCHARIDE; THIOCTIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BODY WEIGHT; CONTROLLED STUDY; DRUG EFFECT; ENDOTOXEMIA; FEMALE; FOOD INTAKE; IMMUNITY; LIVER; MOUSE; NONHUMAN; PEYER PATCH; PHENOTYPE; SMALL INTESTINE; SPLEEN;

ANIMALS; ANTIOXIDANTS; B-LYMPHOCYTES; DIETARY SUPPLEMENTS; ENDOTOXEMIA; FEMALE; GLUTAMINE; GLUTATHIONE; MICE; MICE, INBRED BALB C; THIOCTIC ACID; TIME FACTORS; VITAMIN B COMPLEX;

EID: 33645654793     PISSN: 00435325     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00508-006-0568-3     Document Type: Article

References (36)

1. Baue AE, Durham R, Faist E (1998) Systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), multiple organ failure (MOF): are we winning the battle? Shock 10: 79-89
2. Swank GM, Deitch EA (1996) Role of the gut in multiple organ failure: bacterial translocation and permeability changes. World J Surg 20: 411-417
3. Thomas S, Balasubramanian KA (2004) Role of intestine in postsurgical complications: involvement of free radicals. Free Radic Biol Med 36: 745-756
4. Farstad IN, Halstensen TS, Kvale D, Fausa O, Brandtzaeg P (1997) Topographic distribution of homing receptors on B and T cells in human gut-associated lymphoid tissue: relation of L-selectin and integrin alpha 4 beta 7 to naive and memory phenotypes. Am J Pathol 150: 187-199
5. Li J, Kudsk KA, Janu P, Renegar KB (1997) Effect of glutamine-enriched total parenteral nutrition on small intestinal gut-associated lymphoid tissue and upper respiratory tract immunity. Surgery 121: 542-549
6. Manhart N, Vierlinger K, Bergmeister H, Boltz-Nitulescu G, Spittler A, Roth E (2000) Influence of short-term protein malnutrition of mice on the phenotype and costimulatory signals of lymphocytes from spleen and Peyer's patches. Nutrition 16: 197-201
7. Manhart N, Vierlinger K, Habel O, Bergmeister LH, Gotzinger P, Sautner T, et al (2000) Lipopolysaccharide causes atrophy of Payer's patches and an increased expression of CD28 and B7 costimulatory ligands. Shock 14: 478-483
8. Manhart N, Vierlinger K, Spittler A, Bergmeister H, Sautner T, Roth E (2001) Oral feeding with glutamine prevents lymphocyte and glutathione depletion of Peyer's patches in endotoxemic mice. Ann Surg 234: 92-97
9. Ayala A, Xin Xu Y, Ayala CA, Sonefeld DE, Karr SM, Evans TA, et al (1998) Increased mucosal B-lymphocyte apoptosis during polymicrobial sepsis is a Fas ligand but not an endotoxin-mediated process. Blood 91: 1362-1372
10. Hotchkiss RS, Tinsley KW, Swanson PE, Schmieg RE Jr, Hui JJ, Chang KC, et al (2001) Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans. J Immunol 166: 6952-6963
11. Deneke SM (2000) Thiol-based antioxidants. Curr Top Cell Regul 36: 151-180
12. Exner R, Wessner B, Manhart N, Roth E (2000) Therapeutic potential of glutathione. Wien Klin Wochenschr 112: 610-616
13. Buttke TM, Sandstrom PA (1995) Redox regulation of programmed cell death in lymphocytes. Free Radic Res 22: 389-397
14. Chang WK, Yang KD, Chuang H, Jan JT, Shaio MF (2002) Glutamine protects activated human T cells from apoptosis by up-regulating glutathione and Bcl-2 levels. Clin Immunol 104: 151-160
15. Harward TR, Coe D, Souba WW, Klingman N, Seeger JM (1994) Glutamine preserves gut glutathione levels during intestinal ischemia/reperfusion. J Surg Res 56: 351-355
16. Flaring UB, Rooyackers OE, Wernerman J, Hammarqvist F (2003) Glutamine attenuates post-traumatic glutathione depletion in human muscle. Clin Sci (Lond) 104: 275-282
17. Wessner B, Strasser EM, Spittler A, Roth E (2003) Effect of single and combined supply of glutamine, glycine, N-acetylcysteine, and R,S-alpha-lipoic acid on glutathione content of myelomonocytic cells. Clin Nutr 22: 515-522
18. Sen CK, Roy S, Han D, Packer L (1997) Regulation of cellular thiols in human lymphocytes by alpha-lipoic acid: a flow cytometric analysis. Free Radic Biol Med 22: 1241-1257
19. Hagen TM, Liu J, Lykkesfeldt J, Wehr CM, Ingersoll RT, Vinarsky V, et al (2002) Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress. Proc Natl Acad Sci USA 99: 1870-1875
20. Luo JL, Hammarqvist F, Cotgreave IA, Lind C, Andersson K, Wernerman J (1995) Determination of intracellular glutathione in human skeletal muscle by reversed-phase high-performance liquid chromatography. J Chromatogr B Biomed Appl 670: 29-36
21. Garrel D, Patenaude J, Nedelec B, Samson L, Dorais J, Champoux J, et al (2003) Decreased mortality and infectious morbidity in adult burn patients given enteral glutamine supplements: a prospective, controlled, randomized clinical trial. Crit Care Med 31: 2444-2449
22. Goeters C, Wenn A, Mertes N, Wempe C, Van Aken H, Stehle P, et al (2002) Parenteral L-alanyl-L-glutamine improves 6-month outcome in critically ill patients. Crit Care Med 30: 2032-2037
23. Yoshino K, Sakai K, Okada H, Sakai T, Yamamoto S (2003) IgE responses in mice fed moderate protein deficient and high protein diets. J Nutr Sci Vitaminol (Tokyo) 49: 172-178
24. Bounous G, Batist G, Gold P (1989) Immunoenhancing property of dietary whey protein in mice: role of glutathione. Clin Invest Med 12: 154-161
25. Xu YX, Ayala A, Monfils B, Cioffi WG, Chaudry IH (1997) Mechanism of intestinal mucosal immune dysfunction following trauma-hemorrhage: increased apoptosis associated with elevated Fas expression in Peyer's patches. J Surg Res 70: 55-60
26. Fukuzuka K, Edwards CK 3rd, Clare-Salzer M, Copeland EM 3rd, Moldawer LL, Mozingo DW (2000) Glucocorticoid and Fas ligand induced mucosal lymphocyte apoptosis after burn injury. J Trauma 49: 710-716
27. Exner R, Weingartmann G, Eliasen MM, Gerner C, Spittler A, Roth E, et al (2002) Glutamine deficiency renders human monocytic cells more susceptible to specific apoptosis triggers. Surgery 131: 75-80
28. Manhart N, Spittler A, Bergmeister H, Mittlbock M, Roth E (2003) Influence of fructooligosaccharides on Peyer's patch lymphocyte numbers in healthy and endotoxemic mice. Nutrition 19: 657-660
29. Bone RC, Grodzin CJ, Balk RA (1997) Sepsis: a new hypothesis for pathogenesis of the disease process. Chest 112: 235-243
30. Natanson C, Hoffman WD, Suffredini AF, Eichacker PQ, Danner RL (1994) Selected treatment strategies for septic shock based on proposed mechanisms of pathogenesis. Ann Intern Med 120: 771-783
31. Han D, Handelman G, Marcocci L, Sen CK, Roy S, Kobuchi H, et al (1997) Lipoic acid increases de novo synthesis of cellular glutathione by improving cystine utilization. Biofactors 6: 321-338
32. Suh JH, Wang H, Liu RM, Liu J, Hagen TM (2004) (R)-alpha-lipoic acid reverses the age-related loss in GSH redox status in post-mitotic tissues: evidence for increased cysteine requirement for GSH synthesis. Arch Biochem Biophys 423: 126-135
33. Panigrahi M, Sadguna Y, Shivakumar BR, Kolluri SV, Roy S, Packer L, et al (1996) alpha-Lipoic acid protects against reperfusion injury following cerebral ischemia in rats. Brain Res 717: 184-188
34. Manhart N, Vierlinger K, Akomeah R, Bergmeister H, Spittler A, Roth E (2000) Influence of enteral diets supplemented with key nutrients on lymphocyte subpopulations in Peyer's patches of endotoxin-boostered mice. Clin Nutr 19: 265-269
35. Yamamoto M, Rennert P, McGhee JR, Kweon MN, Yamamoto S, Dohi T, et al (2000) Alternate mucosal immune system: organized Peyer's patches are not required for IgA responses in the gastrointestinal tract. J Immunol 164: 5184-5191
36. Pechan I, Danova K, Olejarova I, Halcak L, Rendekova V, Fabian J. (2003) Oxidative stress and antioxidant defense systems in patients after heart transplantation. Wien Klin Wochenschr 115: 648-651