Therapeutic potential of glutathione

Wiener Klinische Wochenschrift

Volumn 112, Issue 14, 2000, Pages 610-616

  Exne, R ^a   Wessner, B ^a   Manhart, N ^a   Roth, E ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Antioxidants; Glutamine; Glutathione; Reactive oxygen species; Redox potential; Thiols

Indexed keywords

ACETYLCYSTEINE; GLUTAMINE; GLUTATHIONE; REACTIVE OXYGEN METABOLITE; THIOCTIC ACID;

ADJUVANT THERAPY; ANTIOXIDANT ACTIVITY; CANCER; CORONARY ARTERY DISEASE; DIABETES MELLITUS; DRUG EFFICACY; GLUTATHIONE METABOLISM; HUMAN; IMMUNE DEFICIENCY; IMMUNE SYSTEM; INTOXICATION; NONHUMAN; OXIDATION REDUCTION POTENTIAL; PHYSICAL ACTIVITY; PNEUMONIA; REVIEW; SEPSIS; UREMIA;

ACQUIRED IMMUNODEFICIENCY SYNDROME; CHEMOTHERAPY, ADJUVANT; COMMON VARIABLE IMMUNODEFICIENCY; CORONARY DISEASE; CYTOKINES; DIABETES MELLITUS; GLUTATHIONE; HUMANS; IMMUNITY, CELLULAR; LUNG DISEASES; REPERFUSION INJURY; UREMIA;

EID: 0034725947     PISSN: 00435325     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (46)

1. Glutathione
2. In vitro glutathione supplementation enhances interleukin-2 production and mitogenic response of peripheral blood mononuclear cells from young and old subjects
3. Interleukin-2 MRNA expression, lymphokine production and DNA synthesis in glutathione depleted T cells
4. Regulation by glutathione of the effect of lymphokines on differentiation of primary activated lymphocytes
5. Glutathione depletion in rats impairs t-cell and macrophage immune function
6. Thiols decrease human interleukin (IL) 4 production and IL-4-induced immunoglobulin synthesis
7. Tumor necrosis factor-α-mediated decrease in glutathione increases the sensitivity of pulmonary vascular endothelial cells to H'2O'2
8. Treatment with glutathione precursor decreases cytokine activity
9. Glutathione homeostasis in response to exercise training and nutritional supplements
10. Protection effect of endurance training against reoxigenation-induced injuries in rat heart
11. α-Lipoic acid supplementation: Tissue glutathione homeostasis at rest and after exercise
12. Parenteral glutamine protects hepatic function during bone marrow transplantation
13. Parenteral glutathione monoester enhances tissue antioxidant stores
14. Protection against cisplatin toxicity by administration of glutathione ester
15. High-dose intravenous glutathione in man
16. Glutathione reduces the toxicity associated with antitumor therapy of ascites fluid adsorbed over Staphylococcus aureus Cowan I in tumor bearing mice
17. Role of lipid peroxidation and antioxidants in gastric mucosal injury induced by the hypoxanthine-xanthine oxidase system in rats
18. Ebselen, a novel anti-oxidant compound, protects the rat liver from ischemia-reperfusion injury
19. Glutathione and nitric oxide concentrations in glutamine-infused rabbits with intestinal ischaemia/reperfusion
20. Influence of reduced glutathione on glucose metabolism in patients with non-insulin-dependent diabetes mellitus
21. Effect of reduced glutathione on the survival of red blood cells in hemodialyzed patients
22. Glutathione aerosol suppresses lung epithelial surface inflammatory cell-derived oxidants in cystic fibroses
23. Glutathione causes coronary vasodilatation via a nitric oxide- and soluble guanylate cyclase-dependent mechanism
24. Intracoronary infusion of reduced glutathione improves endothelial vasomotor response to acetylcholine in human coronary circulation
25. Glutathione reverses endothelial dysfunction and improves nitric oxide bioavailability
26. Effects of s-nitroso-glutathione in the human forearm circulation: Evidence for selective inhibition of platelet activation
27. Inhibition of platelet activity by s-nitrosoglutathione during coronary angioplasty
28. Glutathione deficiency and human immunodeficiency virus infection
29. Increased levels of oxidized glutatione in CD4+ lymphocytes associated with disturbed intracellular redox balance in human immunodeficiency virus type 1 infection
30. Inhibition of murine AIDS by reduced glutathione
31. Decreased levels of total and reduced glutathione in CD4+ lymphocytes in common variable immunodeficiency are associated with activation of the tumor necrosis factor system: Possible immunopathogenic role of oxidative stress
32. Transport of glutathione diethyl ester into human cells
33. Influence of enteral diets supplemented with key nutrients on lymphocyte subpopulations in Peyer's patches of endotoxin-boostered mice
34. Nutritional biochemistry of cellular glutathione
35. Inflammation and the regulation of glutathione level in lung epithelial cells
36. Modulation of endogenous glutathione availability
37. Glutathione in the prevention of cisplatin-induced toxicities. A prospectively randomized pilot trial in patients with head and neck cancer and non small cell lung cancer
38. Skeletal muscle and liver glutathione homeostasis in response to training, exercise, and immobilization
39. Oxidative stress in muscular atrophy
40. Effects of age on levels of cysteine, glutathione and related enzyme activities in livers of mice and rats and an attempt to replenish hepatic glutathione level with cysteine derivates
41. Effect of liver cirrhosis and age on the glutathione concentration in the plasma, erythrocytes, and gastric mucosa of man
42. Glutathione depletion in chronic hepatitis C
43. Low levels of blood and colonic glutathione in ulcerative colitis
44. Glutathione deficiency in the epithelial lining fluid of the lower respiratory tract in idiopathic pulmonary fibrosis
45. Deficiency of alveolar fluid glutathione in patients with sepsis and the adult respiratory distress syndrome
46. Decreased glutathione levels in acute myocardial infarction