Brain injury: Benzodiazepines, antipsychotics, and functional recovery

Journal of Head Trauma Rehabilitation

Volumn 21, Issue 1, 2006, Pages 82-84

  Perna, Robert ^a  

^a Westside Neurorehabilitation Services   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BENZODIAZEPINE DERIVATIVE; CATECHOLAMINE; DOPAMINE; HALOPERIDOL; KETAMINE; MIDAZOLAM; NEUROLEPTIC AGENT; NORADRENALIN; PSYCHOTROPIC AGENT;

AGITATION; ANXIETY DISORDER; BEHAVIOR DISORDER; BRAIN INJURY; CONVALESCENCE; HIPPOCAMPUS; HUMAN; NEUROPROTECTION; PSYCHOSIS; SHORT SURVEY; DRUG EFFECT; PSYCHOLOGICAL ASPECT; REVIEW;

ANTIPSYCHOTIC AGENTS; BENZODIAZEPINES; BRAIN INJURIES; HUMANS; RECOVERY OF FUNCTION;

EID: 33645639604     PISSN: 08859701     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001199-200601000-00009     Document Type: Short Survey

References (31)

1. Goldstein LB, Bullmans S. Differential effects of haloperidol and clozapine on motor recovery after sensorimotor cortex injury in rats. Neurorehabil Neural Repair. 2002;16(4):1-5.
2. Goldstein LB. Pharmacological approach to functional reorganization: the role of norepinephrine. Rev Neurol. 1999;155:731-736.
3. Boyeson MG, Jones JL. Theoretical mechanisms of brain plasticity and therapeutic implications. In: Horns LJ, Zaslers N, eds. Medical Rehabilitation of Traumatic Brain Injury. Hanley & Belfus Inc: Philadelphia; 1996:90-93.
4. Verma A. Low-tech neuroprotection for brain injury. J Head Trauma Rehabil. 2001;16(2):206-209.
5. Feeney DM. From laboratory to clinic: noradrenergic enhancement of physical therapy for stroke or trauma patients. In: Freud HJ, Sabel BA, Witte OW, eds. Brain Plasticity, Advances in Neurology. Philadelphia: Lippincott-Raven; 1997:383-394.
6. Feeney DM. Rehabilitation pharmacology: noradrenergic enhancement of physical therapy. In: Ginsberg MD, Bogousslavsky J, eds. Cerebrovascular Diseases: Pathophysiology, Diagnosis and Management. Cambridge, UK: Blackwell; 1998:620-636.
7. Goldstein LB. Effects of amphetamines and small related molecules on recovery after stroke in animals and man. Neuropharmacology. 2000;39:852-859.
8. Van Hasselt P. Effect of butyrophenones on motor function in rats after recovery from brain damage. Neuropharmacology. 1973;12:245-247.
9. Goldstein LB, Matchar DB, Morgenlander JC, Davis JN. Influence of drugs on the recovery of sensorimotor function after stroke. J Neuro Rehabil. 1990;4:137-144.
10. Goldstein LB. Sygen in acute stroke study investigators: common drugs may influence motor recovery after stroke. Neurology. 1995;45:865-871.
11. Hayes RL, Jenkins LW, Lyeth BG. Neurotransmitter-mediated mechanisms of traumatic brain injury: acetylcholine and excitatory amino acids. J Neurotrauma. 1992;9(1):173-187.
12. Lyeth BG, Dixon CR, Jenkins LW, et al. Effects of scopalamine treatment on long-term behavioral deficits following concussive brain injury to the rat. Brain Res. 1988;459:39-48.
13. Lyeth BG, Ray M, Hamm RJ, et al. Post-injury scopolamine administration in experimental traumatic brain injury. Brain Res. 1992;569:281-286.
14. Robinson SE, Fox SD, Posner MG, et al. The effect of MI muscarinic blockade on behavior following traumatic brain injury in the rat. Brain Res. 1990;511:141-148.
15. Saija A, Robinson SE, Lyeth BG, et al. The effects of scopalamine and traumatic brain injury on central cholinergic neurons. Neurotrauma. 1988;5:161-170.
16. 2+ influx elicited by glutamate: role in neuronal death. Mol Pharmacol. 1989;36:379-387.
17. Choi DW. Glutamate neurotoxicity and diseases of the nervous system. Neuron. 1988;1:623-634.
18. Law AJ, Hutchinson LJ, Burnet PW, Harrison PJ. Antipsychotics increase microtubule-associated protein 2mRNA but not spinophilin mRNA in rat hippocampus and cortex. J Neurosci Res. 2004;76(3):376-382.
19. Maxa JL, Taleghani AM, Ogu CC, Tanzi M. Possible toxic encephalopathy following high dose intravenous haloperidol. Ann Pharmacother. 1997;31(6):736-737.
20. Sandyk R, Hurwitz MD. Toxic irreversible encephalopathy induced by lithium carbonate and haloperidol. A report of 2 cases. S Afr Med J. 1983;64(22):875-876.
21. Jain JJ. Drug Induced Neurological Disorders. 2nd ed. Seattle: Hogrefe & Huber Publishers; 2001.
22. Xue QS, Yu BW, Wang ZJ, Chen HZ. Effects of ketamine, midazolam, thiopental, and propofol on brain ischemia injury in rat cerebral cortical slices. Acta Pharmacol Sin. 2004;25(1):115-120.
23. O'Dell DM, Gibson CJ, Wilson MS, Deford SM, Hamm R. Positive and negative modulation of the GABA(A) receptor and outcome after traumatic brain injury in rats. Brain Res. 2000;861:325-332.
24. Sims JS, Jones TA, Fulton RL, et al. Benzodiazepine effects on recovery of function linked to transneuronal morphological events. Soc Neurosci Abstr. 1990;16:342.
25. Hernandez TD, Jones GH, Schallert T. Co-administration of Ro15-1788 prevents diazepaminduced retardation of recovery of function. Brain Res. 1989;487(1):89-95.
26. Schallert T, Hernandez TD, Barth TM. Recovery of function after brain damage. Severe and chronic disruption by diazepam. Brain Res. 1986;379:104-111.
27. Sader AA, Barbieri-Neto J, Sader SL, Mazzetto SA, Alves P Jr, Vanni JC. The protective action of chlorpromazine on the spinal cord of rabbits submitted to ischemia and reperfusion is dose-dependent. J Cardiovasc Surg (Torino). 2002;43(6):827-831.
28. Stricker EM, Zigmond MJ. Brain monoamines, homeostasis, and adaptive behavior. In: Mountcastle VB, Bloom FE, Geiger SR, eds. Handbook of Physiology - the Nervous System. Vol 4. Baltimore: Waverly Press; 1986:677-700.
29. Orient-Lopez F, Terre-Boliart R, Bernabeu-Guitart M, Ramon-Rona S, Perez-Miras A. The usefulness of dopaminergic drugs in traumatic brain injury. Rev Neurol. 2002;35(4):362-366.
30. Feeney DM, Gonzalez A, Law WA. Amphetamine, haloperidol, and experience interact to affect rate of recovery after motor cortex injury. Science. 1982;217(4562):855-857.
31. Wilson MS, Gibson CJ, Hamm RJ. Haloperidol, but not olanzepine, impairs cognitive performance after traumatic brain injury in rats. Am J Phys Med Rehabil. 2003;82(11):871-879.