Alterations in urinary bladder synaptosomal neurotransmitter concentrations in two-week streptozotocin-induced diabetic rats

Neuroscience Letters

Volumn 206, Issue 2-3, 1996, Pages 165-168

  Tong, Yat Ching ^a   Hung, Ying Cho ^a   Lin, Shinn Nan ^a   Cheng, Juei Tang ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Diabetes; Neurotransmitter; Synaptosome; Urinary bladder

Indexed keywords

ACETYLCHOLINE; ADRENALIN; DOPAMINE; NEUROTRANSMITTER; NORADRENALIN; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER; CONTROLLED STUDY; DIABETES MELLITUS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NERVE ENDING; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPSE VESICLE;

EID: 0029995140     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(96)12473-3     Document Type: Article

References (16)

1. Bradley, W.E., Diagnosis of urinary bladder dysfunction in diabetes mellitus, Ann. Int. Med., 92 (1980) 323-326.
2. Eva, C., Adjiconstantinou, U., Neff, N.H. and Meek, J.L., Acetylcholine measurement by high-performance liquid chromatography using an enzyme-loaded postcolumn reactor, Anal. Biochem., 143 (1984) 320-324.
3. Gray, E.G. and Whittaker, V.P., The isolation of nerve endings from brain: an electron-microscopic study of cell fragmentation derived by homogenization and centrifugation, J. Anat., 96 (1962) 79-87.
4. Gu, J., Blank, M.A., Huang, W.M., Islam, K.N., McGregor, G.P., Christofides, N., Allen, J.M., Bloom, S.R. and Lolak, J.M., Peptide-containing nerves in human urinary bladder, Urology, 14 (1984) 353-358.
5. Kolta, M.G., Wallace, L.J. and Gerald, M.C., Streptozotocin-induced diabetes affects rat urinary bladder response to autonomic agents, Diabetes, 34 (1985) 917-921.
6. Kudlacz, E.M., Gerald, M.C. and Wallace, L.J., Effects of diabetes and diuresis on contraction and relaxation mechanisms in rat urinary bladder, Diabetes, 38 (1989) 278-281.
7. Latifpour, J., Gousse, A., Kondo, S., Morita, T. and Weiss, R.M., Effects of experimental diabetes on biochemical and functional characteristics of bladder muscarinic receptors, J. Pharmacol. Exp. Ther., 248 (1989) 81-88.
8. Lowry, O.H., Rosebrough, N.J., Farr, A.L. and Randall, R.J., Protein measurement with Folin phenol reagent, J. Biol. Chem., 193 (1951) 265-275.
9. Lundberg, J.M., Evidence for coexistence of vasoactive intestinal polypeptide (VIP) and acetylcholine in neurons of cat exocrine glands, Acta Physiol. Scand. (Suppl.), 496 (1981) 57-60.
10. Paro, M., Italiano, G., Travagli, R.A., Petrelli, L., Zanoni, R., Prosdocimi, M. and Fiori, M.G., Cystometric changes in alloxan diabetic rats: evidence for functional and structural correlates of diabetic autonomic neuropathy, J. Autonomic Nerv. Syst., 30 (1990) 1-12.
11. Paro, M., Prashar, A., Prosdocimi, M., Cherian, P.V., Fiori, M.G. and Sima, A.A., Urinary bladder dysfunction in the BB/W diabetic rat: effect of ganglioside treatment on functional and structural alterations, J. Urol., 151 (1994) 781-786.
12. Santicioli, P., Gamse, R., Maggi, C.A. and Meli, A., Cystometric changes in the early phase of streptozotocin-induced diabetes in rats: evidence for sensory changes not correlated to diabetic neuropathy, Naunyn-Schmiedebergs Arch. Pharmacol., 335 (1987) 580-587.
13. Steers, W.D., Mackway-Gerardi, A.M., Ciambotti, J. and de Groat, W.C., Alterations in neural pathways to the urinary bladder of the rat in response to streptozotocin-induced diabetes, J. Autonomic Nerv. Syst., 47 (1994) 83-94.
14. Tammela T.L., Leggett, R.E., Levin, R.M. and Longhurst, P.A., Temporal changes in micturition and bladder contractility after sucrose diuresis and streptozotocin-induced diabetes mellitus in rats, J. Urol., 153 (1995) 2014-2021.
15. Tong, Y.C., Hung, Y.C., Lin, S.N. and Cheng, J.T., Isolation of synaptosomes from the rat urinary bladder, J. Autonomic Nerv. Syst., (1996) in press.
16. Tong, Y.C., Hung, Y.C., Lin, S.N. and Cheng, J.T., Comparisons of neurotransmitter concentrations in the synaptosomal preparation of the normotensive and hypertensive rat urinary bladder, Neurosci. Lett., (1996) in press.