Enhanced skin permeation of salicylate by ion-pair formation in non-aqueous vehicle and further enhancement by ethanol and l-menthol

Chemical and Pharmaceutical Bulletin

Volumn 54, Issue 4, 2006, Pages 481-484

  Kamal, Mohammad Abu Hena Mostofa ^a   Iimura, Nahoko ^a   Nabekura, Tomohiro ^a   Kitagawa, Shuji ^a,b  

^a NIIGATA UNIVERSITY OF PHARMACY AND APPLIED LIFE SCIENCES   (Japan)

^b KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Alkylamines; Benzylamine; Enhancer; Ion pair; Salicylate; Skin permeability

Indexed keywords

ALCOHOL; ALIPHATIC AMINE; BENZYLAMINE; BUTYLAMINE; CATION; GENTISIC ACID; HEXYLAMINE; LIDOCAINE; MENTHOL; MYRISTIC ACID ISOPROPYL ESTER; OCTYLAMINE; SALICYLIC ACID; SALICYLIC ACID METHYL ESTER;

ADDITION REACTION; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG SOLUBILITY; ENHANCER REGION; ION TRANSPORT; NONAQUEOUS PHASE LIQUID; NONHUMAN; SKIN PENETRATION; SKIN PERMEABILITY; SKIN SURFACE;

ADMINISTRATION, CUTANEOUS; AMINES; ANIMALS; BENZYLAMINES; DRUG INTERACTIONS; ETHANOL; GUINEA PIGS; IONS; MENTHOL; MYRISTATES; PERMEABILITY; SALICYLIC ACID; SKIN ABSORPTION; SOLUBILITY;

EID: 33645551865     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.54.481     Document Type: Article

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