Convergence of multiple pelvic organ inputs in the rat rostral medulla

Journal of Physiology

Volumn 572, Issue 2, 2006, Pages 393-405

  Kaddumi, Ezidin G ^a   Hubscher, Charles H ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

URETHAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLADDER; BLADDER DISTENSION; BRAIN ELECTROPHYSIOLOGY; BRAIN FUNCTION; BRAIN NERVE CELL; COLON; CONCEPT FORMATION; CONTROLLED STUDY; ELECTROSTIMULATION; MALE; MALE GENITAL SYSTEM; MECHANICAL STIMULATION; NERVE STIMULATION; NONHUMAN; PELVIC NERVE; PENIS; PRIORITY JOURNAL; RAT; RETICULAR FORMATION; URETHRA; VAGUS NERVE STIMULATION; COLON DILATATION; MEDULLA OBLONGATA; MEDULLARY RETICULAR FORMATION; STIMULUS RESPONSE;

ACTION POTENTIALS; ANIMALS; BRAIN STEM; COLON; ELECTRIC STIMULATION; ELECTROPHYSIOLOGY; INTRALAMINAR THALAMIC NUCLEI; MALE; NEURONS; PELVIS; PENIS; RATS; RATS, WISTAR; URETHRA; URINARY BLADDER; VAGUS NERVE;

EID: 33645519949     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2005.102574     Document Type: Article

References (72)

1. Almeida A & Lima D (1997). Activation by cutaneous or visceral noxious stimulation of spinal neurons projecting to the medullary dorsal reticular nucleus in the rat: A c-fos study. Eur J Neurosci 9, 686-695.
2. Altschuler SM, Escardo J, Lynn RB & Miselis RR (1993). The central organization of the vagus nerve innervating the colon of the rat. Gastroenterology 104, 502-509.
3. Baez MA, Brink TS & Mason P (2005). Roles for pain modulatory cells during micturition and continence. J Neurosci 25, 384-394.
4. Basinski C, Fuller E, Brizendine EJ & Benson JT (2003). Bladder-anal reflex. Neurourol Urodyn 22, 683-686.
5. Berkley KJ (2005). A life of pelvic pain. Physiol Behav 86, 272-280.
6. Berkley KJ & Hubscher CH (1995). Are there separate central nervous system pathways for touch and pain?Nat Med 1, 766-773.
7. Berkley KJ, Hubscher CH & Wall PD (1993). Neuronal responses to stimulation of the cervix, uterus, colon, and skin in the rat spinal cord. J Neurophysiol 69, 545-556.
8. Bouvier M & Grimaud JC (1984). Neuronally mediated interactions between urinary bladder and internal anal sphincter motility in the cat. J Physiol 346, 461-469.
9. Bouvier M, Grimaud JC & Abysique A (1990). Effects of stimulation of vesical afferents on colonic motility in cats. Gastroenterology 98, 1148-1154.
10. Brodal A, Walberg F, Berkley KJ & Pelt A (1980). Anatomical demonstration of branching olivocerebellar fibres by means of a double retrograde labelling technique. Neuroscience 5, 2193-2202.
11. Cervero F & Laird JM (1999). Visceral pain. Lancet 353, 2145-2148.
12. Cheng HY, Pitcher GM, Laviolette SR, Whishaw IQ, Tong KI, Kockeritz LK, Wada T, Joza NA, Crackower M, Goncalves J, Sarosi I, Woodgett JR, Oliveira-dos-Santos AJ, Ikura M, van der Kooy D, Salter MW & Penninger JM (2002). DREAM is a critical transcriptional repressor for pain modulation. Cell 108, 31-43.
13. Cobos A, Lima D, Almeida A & Tavares I (2003). Brain afferents to the lateral caudal ventrolateral medulla: A retrograde and anterograde tracing study in the rat. Neuroscience 120, 485-498.
14. Dmitrieva N, Johnson OL & Berkley KJ (2001). Bladder inflammation and hypogastric neurectomy influence uterine motility in the rat. Neurosci Lett 313, 49-52.
15. Floyd K, McMahon SB & Morrison JF (1978). Inhibition of the micturition reflex by stimulation of pelvic nerve afferents from the colon. J Physiol 284.P, 39-40P.
16. Foreman RD, Blair RW & Weber RN (1984). Viscerosomatic convergence onto T2-T4 spinoreticular, spinoreticular-spinothalamic, and spinothalamic tract neurons in the cat. Exp Neurol 85, 597-619.
17. Gebhart GF, Sandkuhler J, Thalhammer JG & Zimmermann M (1983). Inhibition of spinal nociceptive information by stimulation in midbrain of the cat is blocked by lidocaine microinjected in nucleus raphe magnus and medullary reticular formation. J Neurophysiol 50, 1446-1459.
18. Griffiths DJ (2002). The pontine micturition centres. Scand J Urol Nephrol Suppl., 21-26.
19. Haber LH, Martin RF, Chung JM & Willis WD (1980). Inhibition and excitation of primate spinothalamic tract neurons by stimulation in region of nucleus reticularis gigantocellularis. J Neurophysiol 43, 1578-1593.
20. Hermann GE, Bresnahan JC, Holmes GM, Rogers RC & Beattie MS (1998). Descending projections from the nucleus raphe obscurus to pudendal motoneurons in the male rat. J Comp Neurol 397, 458-474.
21. Hermann GE, Holmes GM, Rogers RC, Beattie MS & Bresnahan JC (2003). Descending spinal projections from the rostral gigantocellular reticular nuclei complex. J Comp Neurol 455, 210-221.
22. Heruti RJ, Katz H, Menashe Y, Weissenberg R, Raviv G, Madjar I & Ohry A (2001). Treatment of male infertility due to spinal cord injury using rectal probe electroejaculation: The Israeli experience. Spinal Cord 39, 168-175.
23. Holstege G, Griffiths D, de Wall H & Dalm E (1986). Anatomical and physiological observations on supraspinal control of bladder and urethral sphincter muscles in the cat. J Comp Neurol 250, 449-461.
24. Hubscher CH & Berkley KJ (1994). Responses of neurons in caudal solitary nucleus of female rats to stimulation of vagina, cervix, uterine horn and colon. Brain Res 664, 1-8.
25. Hubscher CH & Berkley KJ (1995). Spinal and vagal influences on the responses of rat solitary nucleus neurons to stimulation of uterus, cervix and vagina. Brain Res 702, 251-254.
26. Hubscher CH & Johnson RD (1996). Responses of medullary reticular formation neurons to input from the male genitalia. J Neurophysiol 76, 2474-2482.
27. Hubscher CH & Johnson RD (1999). Effects of acute and chronic midthoracic spinal cord injury on neural circuits for male sexual function. I. Ascending pathways. J Neurophysiol 82, 1381-1389.
28. Hubscher CH & Johnson RD (2003). Responses of thalamic neurons to input from the male genitalia. J Neurophysiol 89,2-11.
29. Hubscher CH & Johnson RD (2004). Effects of chronic dorsal column lesions on pelvic viscerosomatic convergent medullary reticular formation neurons. J Neurophysiol 92, 3596-3600.
30. Hubscher CH, Kaddumi EG & Johnson RD (2004). Brain stem convergence of pelvic viscerosomatic inputs via spinal and vagal afferents. Neuroreport 15, 1299-1302.
31. Jancso G & Maggi CA (1987). Distribution of capsaicin-sensitive urinary bladder afferents in the rat spinal cord. Brain Res 418, 371-376.
32. Johnson RD & Hubscher CH (1998). Brainstem microstimulation differentially inhibits pudendal motoneuron reflex inputs. Neuroreport 9, 341-345.
33. Johnson RD & Hubscher CH (2000). Brainstem microstimulation activates sympathetic fibers in pudendal nerve motor branch. Neuroreport 11, 379-382.
34. Kakizaki H & de Groat WC (1997). Reorganization of somato-urethral reflexes following spinal cord injury in the rat. J Urol 158, 1562-1567.
35. Kruse MN, Noto H, Roppolo JR & de Groat WC (1990). Pontine control of the urinary bladder and external urethral sphincter in the rat. Brain Res 532, 182-190.
36. Longstreth GF (1994). Irritable bowel syndrome and chronic pelvic pain. Obstet Gynecol Surv 49, 505-507.
37. Marson L (1997). Identification of central nervous system neurons that innervate the bladder body, bladder base, or external urethral sphincter of female rats: A transneuronal tracing study using pseudorabies virus. J Comp Neurol 389, 584-602.
38. Marson L & McKenna KE (1990). The identification of a brainstem site controlling spinal sexual reflexes in male rats. Brain Res 515, 303-308.
39. Marson L & McKenna KE (1996). CNS cell groups involved in the control of the ischiocavernosus and bulbospongiosus muscles: A transneuronal tracing study using pseudorabies virus. J Comp Neurol 374, 161-179.
40. Marson L, Platt KB & McKenna KE (1993). Central nervous system innervation of the penis as revealed by the transneuronal transport of pseudorabies virus. Neuroscience 55, 263-280.
41. McCreery DB, Bloedel JR & Hames EG (1979). Effects of stimulating in raphe nuclei and in reticular formation on response of spinothalamic neurons to mechanical stimuli. J Neurophysiol 42, 166-182.
42. McMahon SB & Spillane K (1982). Brain stem influences on the parasympathetic supply to the urinary bladder of the cat. Brain Res 234, 237-249.
43. Milne RJ, Foreman RD, Giesler GJ Jr & Willis WD (1981). Convergence of cutaneous and pelvic visceral nociceptive inputs onto primate spinothalamic neurons. Pain 11, 16-183.
44. Nadelhaft I & Vera PL (2001). Separate urinary bladder and external urethral sphincter neurons in the central nervous system of the rat: simultaneous labeling with two immunohistochemically distinguishable pseudorabies viruses. Brain Res 903, 33-44.
45. Noto H, Roppolo JR, Steers WD & de Groat WC (1989). Excitatory and inhibitory influences on bladder activity elicited by electrical stimulation in the pontine micturition center in the rat. Brain Res 492, 99-115.
46. Paxinos G & Watson C (1998). The Rat Brain in Stereotaxic Coordinates, 3rd edn. Academic Press, San Diego.
47. Prechtl JC & Powley TL (1985). Organization and distribution of the rat subdiaphragmatic vagus and associated paraganglia. J Comp Neurol 235, 182-195.
48. Qin C & Foreman RD (2004). Viscerovisceral convergence of urinary bladder and colorectal inputs to lumbosacral spinal neurons in rats. Neuroreport 15, 467-471.
49. Qin C, Malykhina AP, Akbarali HI & Foreman RD (2005). Cross-organ sensitization of lumbosacral spinal neurons receiving urinary bladder input in rats with inflamed colon. Gastroenterology 129, 1967-1978.
50. Robbins MT, Uzzell TW, Aly S & Ness TJ (2005). Visceral nociceptive input to the area of the medullary lateral reticular nucleus ascends in the lateral spinal cord. Neurosci Lett 381, 329-333.
51. Rouzade-Dominguez ML, Miselis R & Valentino RJ (2003a). Central representation of bladder and colon revealed by dual transsynaptic tracing in the rat: Substrates for pelvic visceral coordination. Eur J Neurosci 18, 3311-3324.
52. Rouzade-Dominguez ML, Pernar L, Beck S & Valentino RJ (2003b). Convergent responses of Barrington's nucleus neurons to pelvic visceral stimuli in the rat: A juxtacellular labelling study. Eur J Neurosci 18, 3325-3334.
53. Roy JC, Bing Z, Villanueva L & Le Bars D (1992). Convergence of visceral and somatic inputs onto subnucleus reticularis dorsalis neurones in the rat medulla. J Physiol 458, 235-246.
54. Russo A & Conte B (1996). Afferent and efferent branching axons from the rat lumbo-sacral spinal cord project both to the urinary bladder and the urethra as demonstrated by double retrograde neuronal labeling. Neurosci Lett 219, 155-158.
55. Salonia A, Zanni G, Nappi RE, Briganti A, Deho F, Fabbri F, Colombo R, Guazzoni G, Di Girolamo V, Rigatti P & Montorsi F (2004). Sexual dysfunction is common in women with lower urinary tract symptoms and urinary incontinence: Results of a cross-sectional study. Eur Urol 45, 642-648.
56. Sauter JF, Niijima A, Berthoud HR & Jeanrenaud B (1983). Vagal neurons and pathways to the rat's lower viscera: An electrophysiological study. Brain Res Bull 11, 487-491.
57. Schoenen J, Delwaide PJ, Legros JJ & Franchimont P (1992). Bulbospinal neuronopathy (letter; comment). Neurology 42, 1252-1253.
58. Seftel AD, Oates RD & Krane RJ (1991). Disturbed sexual function in patients with spinal cord disease. Neurol Clin 9, 757-778.
59. Sugaya K, Ogawa Y, Hatano T, Koyama Y, Miyazato T & Oda M (1998). Evidence for involvement of the subcoeruleus nucleus and nucleus raphe magnus in urine storage and penile erection in decerebrate rats. J Urol 159, 2172-2176.
60. Sugaya K, Ogawa Y, Hatano T, Nishijima S, Matsuyama K & Mori S (2003). Ascending and descending brainstem neuronal activity during cystometry in decerebrate cats. Neurourol Urodyn 22, 343-350.
61. Sugaya K, Roppolo JR, Yoshimura N, Card JP & de Groat WC (1997). The central neural pathways involved in micturition in the neonatal rat as revealed by the injection of pseudorabies virus into the urinary bladder. Neurosci Lett 223, 197-200.
62. Sun W & Panneton WM (2005). Defining projections from the caudal pressor area of the caudal ventrolateral medulla. J Comp Neurol 482, 273-293.
63. Tavares I & Lima D (1994). Descending projections from the caudal medulla oblongata to the superficial or deep dorsal horn of the rat spinal cord. Exp Brain Res 99, 455-463.
64. Truitt WA & Coolen LM (2002). Identification of a potential ejaculation generator in the spinal cord. Science 297, 1566-1569.
65. Van Bockstaele EJ, Akaoka H & Aston-Jones G (1993). Brainstem afferents to the rostral (juxtafacial) nucleus paragigantocellularis: integration of exteroceptive and interoceptive sensory inputs in the ventral tegmentum. Brain Res 603, 1-18.
66. Whorwell PJ, Lupton EW, Erduran D & Wilson K (1986a). Bladder smooth muscle dysfunction in patients with irritable bowel syndrome. Gut 27, 1014-1017.
67. Whorwell PJ, McCallum M, Creed FH & Roberts CT (1986b). Non-colonic features of irritable bowel syndrome. Gut 27, 37-40.
68. Yoshimura N (1999). Bladder afferent pathway and spinal cord injury: possible mechanisms inducing hyperreflexia of the urinary bladder. Prog Neurobiol 57, 583-606.
69. Zermann DH (2002). Efferent control of different visceral pelvic organs by spinal and supraspinal centres. Scand J Urol Nephrol Suppl., 27-33.
70. Zhuo M & Gebhart GF (1990). Characterization of descending inhibition and facilitation from the nuclei reticularis gigantocellularis and gigantocellularis pars alpha in the rat. Pain 42, 337-350.
71. Zhuo M & Gebhart GF (2002a). Facilitation and attenuation of a visceral nociceptive reflex from the rostroventral medulla in the rat. Gastroenterology 122, 1007-1019.
72. Zhuo M & Gebhart GF (2002b). Modulation of noxious and non-noxious spinal mechanical transmission from the rostral medial medulla in the rat. J Neurophysiol 88, 2928-2941.