The tale of early hematopoietic cell seeding in the bone marrow niche

Stem Cells and Development

Volumn 15, Issue 1, 2006, Pages 4-16

  Yaniv, Isaac ^a   Stein, Jerry ^a   Farkas, Daniel L ^b   Askenasy, Nadir ^a  

^a SCHNEIDER CHILDREN S MEDICAL CENTER OF ISRAEL   (Israel)

^b CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA4 INTEGRIN; ALPHA5 INTEGRIN; LEUKOSIALIN;

ANTIGEN EXPRESSION; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CELL ACTIVITY; CELL ADHESION; CELL CULTURE; CELL DIFFERENTIATION; CELL FUNCTION; CELL LINEAGE; CELL MATURATION; CELL MIGRATION; CELL PROLIFERATION; CELL SEEDING; CELL STRUCTURE; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; MICROENVIRONMENT; MITOSIS; NONHUMAN; PRIORITY JOURNAL; REVIEW;

ANIMALS; BONE MARROW; CELL ADHESION; CELL MOVEMENT; FEMUR; GRAFT SURVIVAL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HUMANS; MODELS, BIOLOGICAL;

EID: 33645404354     PISSN: 15473287     EISSN: None     Source Type: Journal    
DOI: 10.1089/scd.2006.15.4     Document Type: Review

References (134)

1. Curry JL, JJ Trentin and N Wolf. (1967). Hemopoietic spleen colony studies. II. Erythropoiesis. J Exp Med 125: 703-720.
2. Wolf NS and JJ Trentin. (1968). Hematopoietic colony studies versus effects of hemopoietic organ stroma on differentiation of pluripotent stem cells. J Exp Med 127: 205-211.
3. Weiss L. (1976). The hematopoietic microenvironment of the bone marrow: an ultrastructural study of the stroma in rats. Anat Rec 186:161-184.
4. Schofield R. (1978). The relationship between the spleen colony-forming cell and the haemopoietic stem cell. Blood Cells 4:7-25.
5. Quesenberry PJ, IK McNiece, BE Robinson, TA Woodward, GB Baber, HE McGrath and PC Isakson. (1987). Stromal cell regulation of lymphoid and myeloid differentiation. Blood Cells 13:137-146.
6. Zipori D. (1989). Stromal cells from the bone marrow: evidence for a restrictive role in regulation of hemopoiesis. Eur J Haematol 42:225-232.
7. Greenberger JS. (1991). The hematopoietic microenvironment. Crit Rev One Hematol 11:65-84.
8. Peled A, M Kalai, J Toledo and D Zipori. (1991). Stroma-cell dependent hematopoiesis. Semin Hematol 28:132-137.
9. Taichman RS. (2005). Blood and bone: two tissues whose fates are intertwined to create the hematopoietic stem-cell niche. Blood 105:2631-2639.
10. Aizawa S and M Tavassoli. (1988). Molecular basis of the recognition of intravenously transplanted hemopoietic cells by bone marrow. Proc Natl Acad Sci USA 85:3180-3183.
11. Voermans C, PB van Hennik and CE van der Schoot. (2001). Homing of human hematopoietic stem and progenitor cells: new insights, new challenges? J Hematother Stem Cell Res 10:725-738.
12. Lapidot T and I Petit. (2002). Current understanding of stem cell mobilization: the roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells. Exp Hematol 30:973-981.
13. Lapidot T and O Kollet. (2002). The essential roles of the chemokine SDF-1 and its receptor CXCR4 in human stem cell homing and repopulation of transplanted immune-deficient NOD/SCID and NOD/SCID/B2m(null) mice. Leukemia 16:1992-2003.
14. Papayannopoulou T. (2003). Bone marrow homing: the players, the playfield, and their evolving roles. Curr Opin Hematol 10:214-219.
15. Quesenberry PJ, G Colvin and M Abedi. (2005). Perspective: fundamental and clinical concepts on stem cell homing and engraftment: a journey to niches and beyond. Exp Hematol 33:9-19.
16. Quesenberry PJ and PS Becker. (1998). Stem cell homing: rolling, crawling, and nesting. Proc Natl Acad Sci USA 95:15155-15157.
17. Juliano RL and S Haskill. (1993). Signal transduction from the extracellular matrix. J Cell Biol 120:577-585.
18. Klein G. (1995). The extracellular matrix of the hematopoietic microenvironment. Experientia 51:914-926.
19. Yoder MC and DA Williams. (1995). Matrix molecule interactions with hematopoietic stem cells. Exp Hematol 23:961-967.
20. van Bekkum DW. (1984). Conditioning regimens for marrow grafting. Semin Hematol 21:81-90.
21. Leong LY, S Qin, SP Cobbold and H Waldmann. (1992). Classical transplantation tolerance in the adult: the interaction between myeloablation and immunosuppression. Eur J Immunol 22:2825-2830.
22. Bradley RR and D Metcalf. (1966). The growth of mouse bone marrow cells in vitro. Aust J Exp Biol Med Sci 44:287-291.
23. Stanley ER and PM Heard. (1977). Factors regulating macrophage production and growth: purification and some properties of the colony stimulating factor from medium conditioned by mouse L-cells. J Biol Chem 252: 4305-4312.
24. Rafii S, F Shapiro, R Pettengell, B Ferris, RL Nachman, MA Moore and AS Asch. (1995). Human bone marrow microvascular endothelial cells support long-term proliferation and differentiation of myeloid and megakaryocytic progenitors. Blood 86:3353-3363.
25. Rafii S, R Mohle, F Shapiro, BM Frey and MA Moore. (1997). Regulation of hematopoiesis by microvascular endothelium. Leuk Lymphoma 27:357-386.
26. Watt SM, LH Butler, M Tavian, HJ Buhring, I Rappold, PJ Simmons, AC Zannettino, D Buck, A Fuchs, R Doyonnas, JY Chan, JP Levesque P, B Peault and I Roxanis. (2000). Functionally defined CD164 epitopes are expressed on CD34(+) cells throughout ontogeny but display distinct distribution patterns in adult hematopoietic and nonhematopoietic tissues. Blood 95:3113-3124.
27. Gekas C, F Dieterlen-Lievre, SH Orkin and HK Mikkola. (2005). The placenta is a niche for hematopoietic stem cells. Dev Cell 8:365-375.
28. Lahiri SK and LM van Putten. (1969). Distribution and multiplication of colony-forming units from bone marrow and spleen after injection in irradiated mice. Cell Tissue Kinet 2:21-28.
29. Testa NG, BI Lord and NA Shore. (1972). The in vivo seeding of hemopoietic colony-forming cell in irradiated mice. Blood 40:654-661.
30. Hendrikx PJ, CM Martens, A Hagenbeek, JF Keij and JW Visser. (1996). Homing of fluorescently labeled murine hematopoietic stem cells. Exp Hematol 24:129-140.
31. Cui J, RL Wahl, T Shen, SJ Fisher, E Recker, D Ginsburg and MW Long. (1999). Bone marrow cell trafficking following intravenous administration. Br J Haematol 107:895-902.
32. Szilvassy S, M Bass, G Van Zant and B Grimes. (1999). Organ-selective homing defines engraftment kinetics of murine hematopoietic stem cells and is compromised by ex vivo expansion. Blood 93:1557-1566.
33. Nibley WE and GJ Spangrude. (1998). Primitive stem cells alone mediate rapid marrow recovery and multilineage engraftment after transplantation. Bone Marrow Transplant 21:345-354.
34. Lanzkron SM, MI Collector and SJ Sharkis. (1999). Hematopoietic stem cell tracking in vivo: a comparison of short-term and long-term repopulating cells. Blood 93:1916-1921.
35. Harrison DE and CM Astle. (1997). Short- and long-term multilineage repopulating hematopoietic stem cells in late fetal and newborn mice: models for human umbilical cord blood. Blood 90:174-181.
36. Zijlmans JM, JW Visser, L Laterveer, K Kleiverda, DP Heemskerk, PM Kluin, R Willemze and WE Fibbe. (1998). The early phase of engraftment after murine blood cell transplantation is mediated by hematopoietic stem cells. Proc Natl Acad Sci USA 95:725-729.
37. Askenasy N and DL Farkas. (2003). In vivo imaging studies of the effect of recipient conditioning, donor cell phenotype and antigen disparity on homing of haematopoietic cells to the bone marrow. Br J Haematol 120: 505-515.
38. Orschell-Traycoff CM, K Hiatt, RN Dagher, S Rice, MC Yoder and EF Srour. (2000). Homing and engraftment potential of Sca-1(+)lin(-) cells fractionated on the basis of adhesion molecule expression and position in cell cycle. Blood 96:1380-1387.
39. Plett P, S Frankovitz and C Orschell-Traycoff. (2002). In vivo trafficking, cell cycle activity, and engraftment potential of phenotypically defined primitive hematopoietic cells after transplantation into irradiated or nonirradiated recipients. Blood 100:3545-3552.
40. Plett PA, SM Frankovitz and CM Orschell. (2003). Distribution of marrow repopulating cells between bone marrow and spleen early after transplantation. Blood 102: 2285-2291.
41. Askenasy N, ES Yolcu, H Shirwan, J Stein, I Yaniv and DL Farkas. (2003). Characterization of adhesion and viability of early seeding hematopoietic cells in the host bone marrow in vivo and in situ. Exp Hematol 31: 1292-1300.
42. Askenasy N, ES Yolcu, H Shirwan, Z Wang and DL Farkas. (2003). Cardiac allograft acceptance after localized bone marrow transplantation by isolated limb perfusion in non-myeloablated recipients. Stem Cells 21:200-207.
43. Berrios VM, GJ Dooner, G Nowakowski, A Frimberger, H Valinski, PJ Quesenberry and PS Becker. (2002). The molecular basis for the cytokine-induced defect in homing and engraftment of hematopoietic stem cells. Exp Hematol 29:1326-1335.
44. Peters SO, ELW Kittler, HS Ramshaw and PJ Quesenberry. (1996). Ex vivo expansion of murine marrow cells with interleukin-3 (IL-3), IL-6, IL-11, and stem cell factor leads to impaired engraftment in irradiated hosts. Blood 87:30-37.
45. Reddy GP, CY Tiarks, L Pang, J Wuu, CC Hsieh and PJ Quesenberry. (1997). Cell cycle analysis and synchronization of pluripotent hematopoietic progenitor stem cells. Blood 90:2293-2299.
46. Traycoff CM, K Cornetta, MC Yoder, A Davidson and EF Srour. (1996). Ex vivo expansion of murine hematopoietic progenitor cells generates classes of expanded cells possessing different levels of bone marrow repopulating potential. Exp Hematol 24:299-306.
47. Bradford GB, B Williams, R Rossi and I Bertoncello. (1997). Quiescence, cycling, and turnover in the primitive hematopoietic stem cell compartment. Exp Hematol 25:445-453.
48. Becker PS, SK Nilsson, Z Li, VM Berrios, MS Dooner, CL Cooper, CC Hsieh and PJ Quesenberry. (1999). Adhesion receptor expression by hematopoietic cell lines and murine progenitors: modulation by cytokines and cell cycle status. Exp Hematol 27:533-541.
49. Cheshier SH, SJ Morrison, X Liao and IL Weissman. (1999). In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells. Proc Natl Acad Sci USA 96:3120-3125.
50. Quesenberry PJ, GA Colvin, M Abedi, JF Lambert, B Moore, D Demers, D Greer, C McAuliffe, M Dooner, LG Lum, E Badiavas and V Falanga. (2003). The marrow stem cell: the continuum. Bone Marrow Transplant. 32 (Suppl 1):S19-S22.
51. Levesque JP, DI Leavesley, S Niutta, M Vadas and PJ Simmons. (1995). Cytokines increase human hemopoietic cell adhesiveness by activation of very late antigen (VLA)-4 and VLA-5 integrins. J Exp Med 181:1805-1815.
52. Kovach NL, N Lin, T Yednock, JM Harlan and VC Broudy. (1995). Stem cell factor modulates avidity of alpha 4 beta 1 and alpha 5 beta 1 integrins expressed on hematopoietic cell lines. Blood 85:159-167.
53. Prosper F, D Stroncek, JB McCarthy and CM Verfaillie. (1998). Mobilization and homing of peripheral blood progenitors is related to reversible downregulation of alpha4 beta1 integrin expression and function. J Clin Invest 101:2456-2467.
54. Yamaguchi M, K Ikebuchi, F Hirayama, N Sato, Y Mogi, J Ohkawara, Y Yoshikawa, K Sawada, T Koike and S Sekiguchi. (1998). Different adhesive characteristics and VLA-4 expression of CD341 progenitors in G0/G1 versus S1G2/M phases of the cell cycle. Blood 92:842-848.
55. Zanjani E, A Flake, G Almeida-Porada, N Tran and T Papayannopoulou. (1999). Homing of human cells in the fetal sheep model: modulation by antibodies activating or inhibiting very late activation antigen-4-dependent function. Blood 94:2515-2522.
56. Pang L, PV Reddy, CI McAuliffe, G Colvin and PJ Quesenberry. (2003). Studies on BrdU labeling of hematopoietic cells: stem cells and cell lines. J Cell Physiol 197:251-260.
57. Szilvassy SJ, TE Meyerrose, PL Ragland and B Grimes. (2001). Differential homing and engraftment properties of hematopoietic progenitor cells from murine bone marrow, mobilized peripheral blood, and fetal liver. Blood 98: 2108-2115.
58. Askenasy N and DL Farkas. (2002). Optical imaging of PKH-labeled hematopoietic cells in recipient bone marrow in vivo. Stem Cells 20:501-513.
59. Nilsson SK, MS Dooner and PJ Quesenberry. (1997). Synchronized cell-cycle induction of engrafting long-term repopulating stem cells. Blood 90:4646-4650.
60. Cerny J, M Dooner, C McAuliffe, H Habibian, K Stencil, V Berrios, J Reilly, J Carlson, AM Cerny, L d'Hondt, B Benoit, JF Lambert, G Colvin, S Nilsson, P Becker and P Quesenberry. (2002). Homing of purified murine lymphohematopoietic stem cells: a cytokine-induced defect. J Hematother Stem Cell Res 11:913-922.
61. Askenasy N. (2002). Localized bone marrow transplantation leads to skin allograft acceptance in non-myeloablated recipients: comparison of intra-bone marrow and isolated limb perfusion. Stem Cells 20:86-93.
62. Murphy GF and R Korngold. (2004). Significance of selectively targeted apoptotic rete cells in graft-versus-host disease. Biol Blood Marrow Transplant 10:357-365.
63. Whetton AD and GJ Graham. (1999). Homing and mobilization in the stem cell niche. Trends Cell Biol 9:233-238.
64. Craddock C, B Nakamoto, R Andrews, GV Priestley and T Papayannopoulou. (1997). Antibodies to VLA4 integrin mobilize long-term repopulating cells and augment cytokine-induced mobilization in primates and mice. Blood 90:4779-4788.
65. Papayannopoulou T, GV Priestley and B Nakamoto. (1998). Anti-VLA4/VCAM-1 induced mobilization requires cooperative signaling through the kit/mkit ligand pathway. Blood 91:2231-2239.
66. Vermeulen M, F Le Pesteur, MC Gagnerault, JY Mary, F Sainteny and F Lepault. (1998). Role of adhesion molecules in the homing and mobilization of murine hematopoietic stem and progenitor cells. Blood 92:894-900.
67. Down J, N Tarbell, H Thames and P Mauch. (1991). Syngeneic and allogeneic bone marrow engraftment after total body irradiation: Dependence on dose, dose rate, and fractionation. Blood 77:661-669.
68. Tavassoli M. (1992). The role of conditioning regimens in homing of transplanted hemopoietic cells. Bone Marrow Transpl 10:15-17.
69. Colson Y, H Li, SS Boggs, KD Patrene, PD Johnson and ST Ildstad. (1996). Durable mixed allogeneic chimerism and tolerance by a nonlethal radiation-based cytoreductive approach. J Immunol 157:2820-2829.
70. Brecher G, JD Ansell, HS Micklem, JH Tjio and EP Cronkite. (1982). Special proliferative sites are not needed for seeding and proliferation of transfused bone marrow cells in normal syngeneic mice. Proc Natl Acad Sci USA 79:5085-5087.
71. Saxe D, SS Boggs and DR Boggs. (1984). Transplantation of chromsomally marked syngeneic marrow cells into mice not subjected to hematopoietic stem cell depletion. Exp Hematol 12:277-283.
72. Wu D and A Keating. (1993). Hematapoietic stem cells engraft in untreated transplant recipients. Exp Hematol 21:251-256.
73. Stewart FM, S Zhong, J Wuu, C Hsieh, SK Nilsson and PJ Quesenberry. (1998). Lymphohematopoietic engraftment in minimally myoeloablated hosts. Blood 91: 3681-3687.
74. Quesenberry P, H Ramshaw, R Crittenden, PJ Quesenberry, H Ramshaw, RB Crittenden, FM Stewart, S Rao, S Peters, P Becker, P Lowry, M Blomberg and J Reilly. (1994). Engraftment of normal murine marrow into non-myeloablated host mice. Blood Cells 20:348-350.
75. Stewart F, R Crittenden, P Lowry, S Pearson-White and PJ Quesenberry. (1993). Long-term engraftment of normal and post 5-fluorouracil murine marrow into normal myeloablated mice. Blood 81:2566-2571.
76. Askenasy N and DL Farkas. (2002). Antigen barriers or available space do not restrict in situ adhesion of hemopoietic cells to bone marrow stroma. Stem Cells 20:80-85.
77. Colvin GA, JF Lambert, M Abedi, CC Hsieh, JE Carlson, FM Stewart and PJ Quesenberry. (2004). Murine marrow cellularity and the concept of stem cell competition: geographic and quantitative determinants in stem cell biology. Leukemia 18:575-583.
78. Rao SS, SO Peters, RB Crittenden, FM Stewart, HS Ramshaw and PJ Quesenberry. (1997). Stem cell transplantation in the normal nonmyeloablated host: relationship between dose, schedule and engraftment. Exp Hematol 25:114-121.
79. Benveniste P, C Cantin, D Hyam and NN Iscove. (2003). Hematopoietic stem cells engraft in mice with absolute efficiency. Nature Immunol 4:708-713.
80. Matsuzaki Y, K Kinjo, RC Mulligan and H Okano. (2004). Unexpectedly efficient homing capacity of purified murine hematopoietic stem cells. Immunity 20:87-93.
81. Ema H and H Nakauchi. (2004). "Homing to Niche," a new criterion for hematopoietic stem cells? Immunity 20:1-2.
82. + thymocytes. Blood 80:2406-2411.
83. Drobyski WR and D Majewski. (1997). Donor gamma delta T lymphocytes promote allogeneic engraftment across the major histocompatibility barrier in mice. Blood 89:1100-1109.
84. - cells in whole bone marrow facilitate the engraftment of hematopoietic stem cells across allogeneic barriers. Immunity 11:579-590.
85. Ruggeri L, M Capanni, E Urbani, K Perruccio, WD Shlomchik, A Tosti, S Posati, D Rogaia, F Frassoni, F Aversa, MF Martelli and A Velardi. (2002). Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants. Science 295:2097-2100.
86. Kaufman CL, YL Colson, SM Wren, S Watkins, RL Simmons and ST Ildstad. (1994). Phenotypic characterization of a novel bone marrow-derived cell that facilitates engraftment of allogeneic bone marrow stem cells. Blood 84:2436-2446.
87. Heike Y, T Ohira, M Takahashi and N Saijo. (1995). Long term human hematopoiesis in SCID-hu mice bearing transplanted fragments of adult bone and bone marrow cells. Blood 86:524-530.
88. Hisha H, T Nishino, M Kawamura and S Ikehara. (1995). Successful bone marrow transplantation by bone grafts in chimeric-resistant combination. Exp Hematol 23:347-352.
89. El-Badri NS, BY Wang, Cherry and RA Good. (1998). Osteoblasts promote engraftment of allogeneic hematopoietic stem cells. Exp Hematol 26:110-116.
90. Taichman RS and SG Emerson. (1998). The role of osteoblasts in the hematopoietic microenvironment. Stem Cells 16:7-15.
91. Yaroslavskiy B, Y Colson, S Ildstad, D Parrish and SS Boggs. (1998). Addition of a bone marrow "facilitating cell" population increases stem cell-derived cobblestone area formation in impaired long-term bone marrow culture stroma. Exp Hematol 26:604-611.
92. Askenasy N, T Zorina, DL Farkas and I Shalit. (2002). Transplanted hematopoietic cells seed in clusters in recipient bone marrow in vivo. Stem Cells 20:301-310.
93. Zhang Y, Y Adachi, Y Suzuki, K Minamino, M Iwasaki, H Hisha, CY Song, K Kusafuka, K Nakano, Y Koike, J Wang, E Koh, Y Cui, C Li and S Ikehara. (2004). Simultaneous injection of bone marrow cells and stromal cells into bone marrow accelerates hematopoiesis in vivo. Stem Cells 22:1256-1262.
94. Askenasy N, J Stein, I Yaniv and DL Farkas. (2003). The topological and chronological patterns of hematopoietic cell seeding in host femoral bone marrow after transplantation. Biol Blood Marrow Transplant 9:496-504.
95. Yoshimoto M, T Shinohara, T Heike, M Shiota, M Kanatsu-Shinohara and T Nakahata. (2003). Direct visualization of transplanted hematopoietic cell reconstitution in intact mouse organs indicates the presence of a niche. Exp Hematol 31:733-740.
96. Nilsson SK and PJ Simmons. (2004). Transplantable stem cells: home to specific niches. Curr Opin Hematol 11:102-106.
97. Rattis FM, C Voermans and T Reya. (2004). Wnt signaling in the stem cell niche. Current Opin Hematol 11:88-94
98. C in the normal mouse femur. Blood 46:65-72.
99. Gong JK. (1978). Endosteal marrow: a rich source of hematopoietic stem cells. Science 199:1443-1445.
100. s in DNA synthesis in bone marrow from different bone regions. Experientia 36:459-461.
101. Lambertsen RH and L Weiss. (1984). A model of intramedullary hematopoietic microenvironment based on stereologic study of the distribution of endocloned marrow colonies. Blood 63:287-297.
102. Fan H, R Yasumizu, K Sugiura, N Oyaizu, Y Ohnishi, F Takao, M Inaba, J Liu and S Ikehara. (1990). Histogenesis of hematopoietic bone marrow in adult mice. Exp Hematol 18:159-166.
103. Lord BI. (1990). The architecture of bone marrow cell populations. Int J Cell Cloning 8:317-331.
104. Nilsson SK, HM Johnston and JA Coverdale. (2001). Spatial localization of transplanted hemopoietic stem cells: inferences for the localization of stem cell niches. Blood 97:2293-2299.
105. Nilsson SK, ME Debatis, MS Dooner, JA Madri, PJ Quesenberry and PS Becker. (1998). Immunofluorescence characterization of key extracellular matrix proteins in murine bone marrow in situ. J Histochem Cytochem 46:371-377.
106. Driessen RL, HM Johnston and SK Nilsson. (2003). Membrane-bound stem cell factor is a key regulator in the initial lodgment of stem cells within the endosteal marrow region. Exp Hematol 31:1284-1291.
107. Giancotti FG, PM Comoglio and G Tarone. (1986). Fibronectin-plasma membrane interaction in the adhesion of hematopoietic cells. J Cell Biol 103:429-437.
108. Vuillet-Gaugler MH, J Breton-Gorius and W Vainchenker. (1990). Loss of attachment of fibronectin with terminal human erythroid differentiation. Blood 75:865-873.
109. Koenigsmann M, JD Griffin, J DeCarlo and SA Cannistra. (1992). Myeloid and erythroid progenitor cells from normal bone marrow adhere to collagen type I. Blood 79:657-665.
110. Long MW, R Briddell, AW Walter, E Bruno and R Hoffman. (1992). Human hematopoietic stem cell adherence to cytokines and matrix molecules. J Clin Invest 90: 251-255.
111. Arai F, A Hirao, M Ohmura, H Sato, S Matsuoka, K Takubo, K Ito, GY Koh and T Suda. (2004). Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell 118:149-161.
112. Avecilla ST, K Hattori, B Heissig, R Tejada, F Liao, K Shido, DK Jin, S Dias, F Zhang, TE Hartman, NR Hackett, RG Crystal, L Witte, DJ Hicklin, P Bohlen, D Eaton, D Lyden, F de Sauvage and S Rafii. (2004). Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis. Nature Med 10:64-71.
113. Stein J, I Yaniv and N Askenasy. (2005). Critical early events in hematopoietic cell seeding and engraftment. Folia Histochem Cytobiolog 43:191-195.
114. Fuchs E and JA Segre. (2000). Stem cells: a new lease on life. Cell 100:143-155.
115. Crean SM, JP Meneski, TG Hullinger, MJ Reilly, EH DeBoever and RS Taichman. (2004). N-linked sialyated sugar receptors support haematopoietic cell-osteoblast adhesions. Br J Haematol 124:534-546.
116. Taichman RS, MJ Reilly and SG Emerson. (1996). Human osteoblasts support human hematopoietic progenitor cells in in vitro bone marrow cultures. Blood 87:518-524.
117. Gordon MY, GP Riley, SM Watt and MF Greaves. (1987). Compartmentalization of a haematopoietic growth factor (GM-CSF) by glycosaminoglycans in the bone marrow microenvironment. Nature 326:403-405.
118. Anklesaria P, J Teixido, M Laiho, JH Pierce, JS Greenberger and J Massague. (1990). Cell-cell adhesion mediated by binding of membrane-anchored transforming growth factor a to epidermal growth factor receptors promotes cell proliferation. Proc Natl Acad Sci USA 87:3289-3293.
119. Bruno E, SD Luikart, MW Long and R Hoffman. (1995). Marrow-derived heparin sulfate proteoglycan mediates the adhesion of hemotopoietic progenitor cells to cytokines. Exp Hematol 23:1212-1217.
120. van der Loo J and R Ploemacher. (1995). Marrow- and spleen-seeding efficiencies of all murine hematopoietic stem cell subsets are decreased by preincubation with hematopoietic growth factors. Blood 85:2598-2606.
121. Traycoff CM, K Cornetta, MC Yoder, A Davidson and EF Srour. (1996). Ex vivo expansion of murine hematopoietic progenitor cells generates classes of expanded cells possessing varying levels of bone marrow repopulating potentials. Exp Hematol 24:299-306.
122. Gothot A, J van der Loo, W Clapp and E Srour. (1998). Cell cycle-related changes in repopulating capacity of human mobilized peripheral blood CD341 cells in non-obese diabetic/severe combined immunedeficient mice. Blood 92:2641-2649.
123. Glimm H, IL-H OH and CJ Eaves. (2000). Human hematopoietic stem cells stimulated to proliferate in vitro lose engraftment potential during their S/G2/M transit and do not reenter GO. Blood 96:4185-4193.
124. Oostendorp RA, J Audet and CJ Eaves. (2000). High-resolution tracking of cell division suggests similar cell cycle kinetics of hematopoietic stem cells stimulated in vitro and in vivo. Blood 95:855-862.
125. Zhang J, C Niu, L Ye, H Huang, X He, WG Tong, J Ross, J Haug, T Johnson, JQ Feng, S Harris, LM Wiedemann, Y Mishina and L Li. (2003). Identification of the haematopoietic stem cell niche and control of the niche size. Nature 425:836-841.
126. Calvi LM, GB Adams, KW Weibrecht, et al. (2003). Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 425:841-846.
127. Murphy MJ, A Wilson and A Trumpp. (2005). More than just proliferation: Myc function in stem cells. Trends Cell Biol 15:128-137.
128. Johnson A and K Dorshkind. (1986). Stromal cells in myeloid and lymphoid long-term bone marrow cultures can support multiple hemopoietic lineages and modulate their production of hemopoietic growth factors. Blood 6:1348-1354.
129. Gupta P, BR Blazar, K Gupta and CM Verfaillie. (1998). Human CD34(+) bone marrow cells regulate stromal production of interleukin-6 and granulocyte colony-stimulating factor and in crease the colony-stimulating activity of stroma. Blood 91:3724-3733.
130. Bilko NM, IA Votyakova, SV Vasylovska and DI Bilko. (2005). Characterization of the interactions between stromal and haematopoietic progenitor cells in expansion cell culture models. Cell Biol Int 29:83-86.
131. Yan F, M Collector, S Tyszko and SJ Sharkis. (2003). Using divisional history to measure hematopoietic stem cell self-renewal and differentiation. Exp Hematol 31:56-64.
132. + cells to fibronectin in an activation-dependent way. Blood 81:344-351.
133. Hurley R, J McCarthy and C Verfaillie. (1995). Direct adhesion to bone marrow stroma via fibronectin receptor inhibits hematopoietic progenitor proliferation. J Clin Invest 124:511-519.
134. Cui L, V Ramsfjell, OJ Borge, OP Veiby, S Lok and SE Jacobsen. (1997). Thrombopoietin promotes adhesion of primitive human hemopoietic cells to fibronectin and vascular cell adhesion molecule-1: role of activation of very late antigen (VLA)-4 and VLA-5. J Immunol 159: 1961-1969.